Here to explain: so this happened to me when I tried to romance her for the first time. So the reason this happens is bc he didn’t take the long rest after he got Karlach the second piece of infernal iron. When u do take a long rest after you help her condition, she will want to talk to you and “get closer to you”. However, if you don’t take that long rest, you probably won’t get that prompt. To my knowledge at least.
i had it happen my first playthrough, if you didnt long rest enough/at the right time in act 2 and don't trigger her romance scene, she says this when you talk to her as you're going into act 3. I was able to fix it be reloading a save before I left act 2 and long rested like 4 times lmao