Immunology | Inflammation: Vascular Events: Part 1

Подписаться 3,2 млн

Просмотров 1,5 млн

50% 1

Official Ninja Nerd Website: ninjanerd.org
Ninja Nerds!
Join Professor Zach Murphy in this four part lecture series where we talk about the physiology of inflammation. In part 1 of this lecture we discuss the vascular events that involve the local chemical mediators, as well as leukocytosis, margination, diapedesis, and positive chemotaxis. We hope you enjoy this lecture and be sure to support us below!
Inflammatory Response Video Series:
Part 1: • Immunology | Inflammat...
Part 2: • Immunology | Inflammat...
Part 3: • Immunology | Inflammat...
Part 4: • Immunology | Inflammat...
References:
● Le T, Bhushan V, Sochat M, Chavda Y, Zureick A. First Aid for the USMLE Step 1 2018. New York, NY: McGraw-Hill Medical; 2017
● Marieb EN, Hoehn K. Anatomy & Physiology. Hoboken, NJ: Pearson; 2020.
● Boron WF, Boulpaep EL. Medical Physiology.; 2017.
● Urry LA, Cain ML, Wasserman SA, Minorsky PV, Orr RB, Campbell NA. Campbell Biology. New York, NY: Pearson; 2020.
● Jameson JL, Fauci AS, Kasper DL, Hauser SL, Longo DL, Loscalzo J. Harrison's Principles of Internal Medicine. New York etc.: McGraw-Hill Education; 2018.
● Iberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P . Molecular Biology of the Cell. New York, NY: Garland Science; 2002
● Murphy K, Weaver C. Janeway's Immunobiology. Garland Science; 2016
● Doan T, Melvold R, Viselli S, Waltenbaugh C. Immunology. Lippincott Williams & Wilkins; 2012
● Levinson W. Review of Medical Microbiology and Immunology. Lange; 2012
● Soman N Abraham. ResearchGate [digital image] Retrieved from: www.researchga... 2011
● The University of Western Australia. [digital image] from: www.meddent.uwa.edu.au/__data/assets/pdf_file/0018/3036123/PATH2220-2017-Lecture-4-Inflammation-1.pdf
Join this channel to get access to perks:
/ @ninjanerdofficial
APPAREL |
We are switching merchandise suppliers.
DONATE
PATREON | / ninjanerdscience
PAYPAL | www.paypal.com...
SOCIAL MEDIA
FACEBOOK | / ninjanerdlectures
INSTAGRAM | / ninjanerdlectures
TWITTER | / ninjanerdsci
@NinjaNerdSci
DISCORD | / discord
#ninjanerd #Inflammation #Immunology

Опубликовано:

1 окт 2024

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист

Посмотреть позже

Комментарии : 775

@madrid22j 6 лет назад

god has blessed us with your existence

@Bilbus7 5 лет назад

madrid22j Has God also blessed us with horrible diseases too?

@raanoooshh9296 5 лет назад

@@Bilbus7 Don't be that person ...

@Bilbus7 5 лет назад

@@raanoooshh9296 A logical and not fond of bullshit type of person?

@raanoooshh9296 5 лет назад

@@Bilbus7 pfftt why are you being so negative did you step on a lego? You're not logical anywhere bruh.

@Bilbus7 5 лет назад

@@raanoooshh9296 How am I not logical anywhere? Clearly you believe in fairytales too.

@lawrencelockhart7739 3 года назад

Murphy is a rare and fabulous lecturer. Don't pressure him to go faster to fit the production time or you'll wreck the delivery to the listener.

@HibaJasim-y1e Год назад

What pressure ... i thought the video lasted just 5 minutes and when it ended i said what the hell the video seemed 5 minutes long

@prameeth 3 года назад

Ninja nerd is going to reach a million student subscribers in a few days. HOW COOL IS THAT! 🤜🤛

@maxillarycanine4443 6 лет назад

instead of netflix, i open youtube for THIS, YOU ARE GREAT GUYS!!

@meganletavish3333 4 года назад

me too such a relief right?

@Morning_Owl_O_O 3 года назад

@@meganletavish3333 yup

@JoTKirk 6 лет назад

When you called TNF-alpha a MOFO I just about died. Librarians givin me the stink eye. Thanks!! (No, really, thank you! Great info)

@mohammedahmedjalloh531 4 года назад

NOT TO OVER-COMMENT "I JUST WANNA SAY THANK YOU FOR MAKING MY STAYHOME LEARNING EFFECTIVE.

@gagegomez1 4 года назад

“WHO THE FRICK DID THAT?!”

@simplymaureen-vw1lf 4 года назад

Zachary Murphy... God's gift to medicine

@13obbyviral77 3 года назад

The best of the best ever🔥🔥🔥🧪

@Tself02 6 лет назад

Just received my grade for my last test on the immune system and Urinary system. I got a B! Ever since I started using your videos as part of my study program, I have been able to make above average grades! Thank you so much for all of your help! ..Reproduction is next!

@NinjaNerdOfficial 6 лет назад

+Tiffany Selrick So glad we could help Tiffany! Make sure to tell your friends! Keep studying!

@haematologistparvaizwar6803 5 лет назад

@@NinjaNerdOfficial sir plz I can't understand.. If we are giving BCG vaccination to newborn, but instid of that why people are infected by mycobacterium TB, and sir why can't we apply BCG again after some age two or three times, so that long term immunity can be developed against it.

@cibisaravanan929 4 года назад

@@haematologistparvaizwar6803 BCG can only be protective against the meningitis and disseminated TB in children. It does not prevent neither the primary infection nor the reactivation of latent pulmonary infection. - WHO

@st.jamesivey9052 2 года назад

@pranoydas140 6 лет назад

You deserve 10M subs

@iqra4397 4 года назад

So true❤

@mrsamandabernier 3 года назад

How are they not at 1 million yet?!?!

@Choogaleh 5 лет назад

Nurse practitioner student here. This is helping understand inflammation for my advanced pathophysiology course. :) Thank you so much!!

@HollywoodWestern 4 года назад

Jennifer N where are you a student at?

@aylinelifgokce6026 2 года назад

"keep your mind clear its cyclooxiginase" hahahhahahahahahahahahahahahhaha. died

@michaelcrew5851 4 года назад

7:57 keep your mind clear , it's cyclooxygenase 😁😁😁😁😁

@rachelshekinah5834 5 лет назад

Pls make pathology videos🙏🙏🙏🙏🙏🙏

@HockeyGirl-cg8hb 5 лет назад

I second this motion!

@neurosurgerypassion2139 5 лет назад

bro use OSMOSIS for pathology

@linaletsgo9466 4 года назад

try taking B vitamins (B9 and B12 - this will relieve vascular inflammation. B12 is methylcobalamin) and essential phospholipids (lecithin). Coenzyme Q10 also helps. In one of my videos I talked about the fact that when I was given intravenous cytoflavin (and these are just B vitamins), I felt very good. Then I did not understand why. B12 should be more than 500 according to the test results - then homocysteine will decrease

@dranthonyasturi9790 2 года назад

I absolutely adore these lectures. I am both an MD and a PhD but limit my activities to electrophysiology here in Italy. Whoever does not appreciate your lectures with the thumb down, either should not be in the field of medicine or simply do not have what it takes to follow any discipline within the scientific spectrum. You are more knowledgeable and much more clear than many professors I have met in the U.S, and Europe. I refer to you as the "SOLISTA VENETO" di Padova where I had training in electrophysiology and hemodynamics

@NinjaNerdOfficial 2 года назад

You should join the Discord! We have some electro-cardio folks and perfusionists who just love to talk ECG case studies! discord.com/invite/Jzd3fYbAa4 or link in the Channel Description

@MohammedKhan-j2d 11 месяцев назад

Where are you based in the USA I would like to meet you Just say thank you for being such a great blessing to humanity

@leonardopeixoto5162 5 лет назад

You're such a freaking good teacher!

@linaletsgo9466 4 года назад

@chestnutsev7 3 года назад

Yes be careful and read the label because I learnt and I’m nobody in this field that there’s two kinds of b12 methylcobalamin and cyanacobalamin the latter not good I believe.

@戴源成-e3e Год назад

Bro I got all the respect for you, but I would like to remind you that at 22:14 P-CAM should be modified as PECAM, which stands for Platelet Endothelial Cell Adhesion Moleclue. As a MD student and immunology researcher from Taiwan, I would like to thank you for producing these high quality videos that provide me and my classmates with plenty of food for thought. Wish you all the best.

@jiixuyr 10 месяцев назад

الله يهديه ويدخل الاسلام , انسان نظيف وصالح 💞💞

@wolfie5470 4 года назад

You saved me many times, Zach! And now I am so happy that I can learn the basics of Immunology with you. Our teacher told us we don't have much time during the lessons so she goes through everything very quickly and told us that we have to learn it at home on our owns. Well, it's kind of a waste of time because I was just sitting there and didn't understand anything - it was so quick and she acted like we should get all the stuff that was in her presentation - the activation of complement almost killed me. We were just staring at her and thought she was crazy, haha. I am sure she is intelligent so much but she probably can't imagine how hard and complicated it is for us to learn and understand because almost everything is completely new stuff. You, Zach, have a gift and you really know how to explain everything so easily. So many doctors/professors/teachers with 4 degrees should learn from YOU how to teach students. THANK YOU SO MUCH xoxo

@zerolingping7047 3 года назад

You deserve 10M subs

@Rasha.Ishtar Год назад

Aren’t phagocytes the first cells in the inflammatory process? Or to be specific dendritic cells? I don’t understand why it’s mast cells in the video can you explain this please? Thank you

@franciscogutierrez6920 6 лет назад

Passed my Hematology exam with your other Videos thank you sooo much man. I'm a visual learner and these videos really help me see the info come to life out the book.

@rewakaur7375 Год назад

Hello Ninja Nerd, I have no words for how grateful I feel to have access to this knowledge! Thank you so much for your work! Due to my ADHD I always struggled with my textbooks and notes reading material and these videos are a big blessing for my visual learner brain! thank you for your efforts!!! I'm getting way more than passing marks in my anatomy classes! Thank you AGAIN! Got bless :)

@wahabdilawar Год назад

You don't have ADHD. You were just "too quick" to misdiagnose yourself.

@bansurikolathur7027 Год назад

Hey Dr. Zach , I beg you 😭😭🙏🙏 please make videos on TYPES OF HYPERSENSITIVITY REACTIONS . please 😔 🙏 😔 🙏 😔 🙏 😔 🙏 😔 🙏.

@suethrillingtales9942 Год назад

Yes I need it too my exam is on 4 January

@dinaghulyan 4 года назад

Thank you so much for ALL your efforts. I cannot imagine anybody can ever explain this topic in a better way. The BEST explanation EVER!!!!

@gultekinunal 2 года назад

Just passed my doctroral qualification exam with great help with your immunology videos! You are awesome man! I did my master's in Microbiology, I tought I learned a lot but I was wrong. I learnt a lot from your videos. Just for the info, if you make a video about hipersentivity types that is going to be awesome, too! Greetings from Turkey!

@ranookukoo9632 Год назад

Hi my microbiology mate ..... From Pakistan 🇵🇰

@fallond3013 4 года назад

I am currently enrolled in a Chinese medicine program, and your videos help me out so much with anatomy. Also couldn't help but notice your cupping marks on the back of your neck! So great, thanks for all the important info.

@tibayounis9977 3 года назад

I wanna source that dr ninja gonna fallow it please 😭😭

@mboe94 5 лет назад

I always go to your page, when there's something I dont entirely understand at med school. Thank you for making these videos!

@andrewlaird2407 4 года назад

How on earth do you remember all this! Absolute legend

@ishaqureshi402 Год назад

I wish I could give you more than just one view because you are saving my life while my professor's earning six digits by just reading through the slides. Gosh! Thank You.

@chrisatronx 4 года назад

This is the best description of this process I have ever seen. This is channel is GOLD. G O L D!

@nafeejal 5 лет назад

please make video on hypersensitivity reactions!

@mangographieellen 3 года назад

I just had to cry because my exam is tomorrow and I hadn't gotten around to this topic until last minute and I'm just so grateful that I can always count on you to explain a topic

@bethanyweston91 Год назад

I got 83% on my last test because of your lecture videos! :)

@Patzili321 6 лет назад

keep your mind clear!! >.> NO

@bernadettesison5979 Год назад

If a gallbladder was removed would a kidney stone be infected with a UTI? Curiosity on mood. Thank you if someone can recall if anemia can cause a body immunization?

@ronelgallon6949 4 года назад

BLESS YOUR HEART THANK YOU FOR DOING SUCH A GREAT JOB! CAN YOU ALSO DISCUSS WOUND HEALING PLEASE!

@HyphyWifey620 5 лет назад

WHO DA FRICK DID THAT?!

@_.zain._. 3 года назад

kinda sus bro

@nwheelhouse6768 3 года назад

Thank you NN, this was so useful! Any chance of a chronic inflammation video being released?

@ramshamahmood6413 4 года назад

Best and easy to understand explanation, thank you !!!!!! Love your work, it's really helping me get through med school.

@minisman9596 4 года назад

Your videos are amazing, saving me in so many subjects. And it makes just fun to study with your videos. Thanks a lot from a 3rd year medical student!

@j-em5762 5 лет назад

Hello! I think you mistook kallikreins as kalikiren in the video, and I suggest you include that in the closed captions or annotations (so you won't need to upload a corrected video). But otherwise, great explanation!

@kotencwto0o 5 лет назад

You're so good at explaining so complicated mechanisms! I passed one exam thanks to another video of yours last week and I think I'm gonna need this video for my next exam this week! 😁 You're awesome! 😊😊

@stephanie9499 3 года назад

There is no God except Allah, prophet Muhammad is the messenger of Allah❤✨

@SiekerMusic 3 года назад

THIS IS SO HELPFULL!!!!!!!! I am so glad there´s a video of this subject since our lecturer wasn't teaching us this clearly as you are doing!! THAAAAANKS!

@robinsonsemakula1454 4 года назад

U are legit😐

@sukeshsubaharan32 5 лет назад

At 5:38, it probably should be kallikrein and not kallikiren

@RehanAli-ju2xn 2 года назад

I wish you Were my friend 😛 awesome lecture and very easy explanation

@Tinyteacher1111 3 года назад

I’m not even in med school; I’m just trying to heal from toxins. This is fascinating, and I’ve found out a lot about why this happened to me!

@louisprusa9833 2 года назад

toxins...LMFAO

@Tinyteacher1111 2 года назад

@@louisprusa9833 That’s funny? Why? I almost died.

@angelat3238 2 года назад

I could barely make it through reading the pages in the pathophysiology book I have, and I would start nodding off. You take pages and pages of confusion and turn it into a visual everyone can interpret. Thank you...

@alphonseahortensis683 4 года назад

I'm completly depending on your lectures sir.pls do more pathology and medicine lectures

@namweebyasumaiyah4748 2 года назад

🥳

@Andreaiscray Год назад

Nobody notice that big spot on his neck? Looks like its from cupping idk

@nerd3390 Год назад

There is no translation 9:13 Please solve the problem my English is bad and I need a translation to understand

@АнастасияДробан 4 года назад

My brain on 18.27: "Limp Bizkit - Rollin' " mode on

@wahabdilawar Год назад

..."this mo-fo- right here..." had me in stitches...😀 @29:21

@grade12revision Год назад

Recap starts at 27:32

@thebeatup44 Год назад

no i will not keep my mind clear on ciclo-oxigenase or else i can't remember the damn thing

@Masmaskias 3 года назад

Oh my god, I am in nursing school and currently taking patho and pharm. This totally helped me! Thank you so much, you are the BEST!! Subscribed and gave you a thumbs up! Thank you! Thank you! Thank you! ❤

@shilpakelkar4269 3 года назад

i am just in awe of your lectures . They are just very well explained . very methodical

@drdineshpahlajani6199 4 года назад

Wow....u are a great teacher.... Explanation to immunology basics at its best...!!! Thanks buddy...

@muhwezironnie2568 6 лет назад

am a pharmaceutical science student first year in mbarara university Uganda thank you man GOD BLESS YOU SO MUCH

@ReginaFarfalla 4 года назад

YOU LEGEND!!!!!! i passed my compleeete physiology exam including neuro thank you!

@margaretmcduck5381 7 месяцев назад

Ok, I can't believe he explained this so well 😮 I was trying to study with the help of every textbook I could find, but it seemed damn near impossible and i was feeling like a giant loser, but then I found you. Thank you so much

@gigubot5941 4 года назад

Alright so nobody here is going to talk abou the 2 circular red spots on his neck all the time talking about red spots and swelling😂😂 btw*might be cupping* anyway I love your videos man their really enjoyfull😍

@OpnieuwGezond 4 года назад

I think it's cupping indeed!

@tariqhassan7306 3 года назад

An amazing and unparalleled teacher ever existing on earth. Love you sir.

@nadakudititab405 Год назад

This is just speechless... very well explained... you are really talented

@d7mii_amoudi957 5 лет назад

Please genius don’t stop making videos 😥😥😥😥

@tycoonerr 6 лет назад

Thanks for all your videos. You make something difficult to understand much easier, FUN and EXCITING!!!

@kipngetichobed6194 3 года назад

Murphy i really like your work, u've helped alot of people.. thanks alot🤗

@SMass-ey8er 4 года назад

Quick recap: 27:19 Thanks for the super video ;)

@amalayoub5478 4 года назад

If I pass my NBDE1 it will be mainly because of you! ❤ thank you so much for all these videos!

@gilsondantas9870 3 года назад

MUUUUITO bom, meu caro!! Explicação clara, direta e muito convincente!! Parabéns!!! [I liked very much of your explanation, very clear, thank you, buddy!!!]

@enkhtuvshinkhorolgarav 4 года назад

I will be a teacher like you, one day. Thanks for being such a role model for me.

@linaletsgo9466 4 года назад

@aaliamustafa1509 2 года назад

Zach please make a series for understanding general pathology and general pharmacology, please ita. A request from me...i have tried like more than 100 videos but in vain...even if i understand, i forget it....only your videos can help...please please make a video on general path, pharm and micro..only general part..pleasssseeee

@mariiakolesnikova2635 4 года назад

I want a smart boyfriend like you ! Videos help me a lot with my physical therapist assistance program! Thank you

@simplymaureen-vw1lf 4 года назад

.... and nothing less!!! You only get what you allow, make no test dummy allowances.

@MulkiAhmedkheir 8 дней назад

Anyone from kenya🇰🇪🇰🇪🇰🇪

@soulsmith-bg9ub Год назад

You are great and wonderful ❤, I wish you continued Immunology Lack of information in this era, really suffer us😢

@irinaserpi9437 6 лет назад

I love you so much! couldn’t pass my exams without you!

@saadmaath1189 Год назад

I feel so hyped after watching you explaining the lecture but I do not know what to do next how to keep those info from being lost

@vanwhosits5539 Год назад

You either need to apply it directly (like in a testing or physical assessment) and I would highly recommend rewatching the video. I've used this process to get through my A&P classes. Just watching this series over and over until I can quote it while I'm watching it (or almost) The key to retention is ALWAYS repetition. Emotional attachment helps, but repetition should always be the default. Repetition to the point of "muscle memory" (being able to recall without effort) is the BEST way to hold on to a concept. The secondary (but also very important, path to memory) is understanding. If you can talk your way through it using something like "if/then" statements, you'll be able to remind yourself of what you've learned. If I see swelling, I know that's because of a fluid build up, what causes fluid build up? cytokines that communicate to the inflammatory hormones...etc. I hope this helps. This is the process that got me through A&P and EMT school.

@vanwhosits5539 Год назад

Hence why I'm watching this vid again, even though I've been done with this particular A&P class from about 4 years. Continuing education always requires repetition.

@greenbandage6206 3 года назад

7:56 🤣🤣🤣🤣🤣 you deserve a like just there

@anmolyadav1855 3 года назад

Showing gratitude to the best teacher I've learnt from. You are AMAZING!

@youreworthyourweightinavoc7189 2 года назад

This was so helpful. I really find the level of detail you give helps me better understand the processes. Thanks heaps!

@suiteritch 4 года назад

how come i dont feel sleepy and i never yawn watching and listening your vids! 😍

@fay5805 4 года назад

This was so helpful. I have been watching a lot of videos on inflammation but this made a perfect picture in my head. thanks a lot.

@m.s.b4332 5 лет назад

21:28 I laughed so much :D. Thanks for your amazing videos.

@WS-xc4yp 4 года назад

How the hell did i just find you now. Hot guy explaining in such passion and super smart.....wow. subscribed str8 away😍😍😍😍😘😘😘😘

@davidcooper177 2 года назад

It is not only IQ. He is gifted with a photographic memory. If the brain does not remember information, no matter how intelligent one is no learning will take place.

@Vwgti2011 11 месяцев назад

Great video! So interactive, great personality, amazing content. Can't get enough of this... Note: A correction for 14:30 - Leukotrienes cause smooth muscle contractions, not relaxation (additionally, constrict airways)

@jeffsteen9331 Год назад

i am going to find you and kiss you

@katiele1989 4 года назад

this is the very first time in my school journey I do understand what I learned from school, You are an amazing teacher, thank you so much

@desertking887 Месяц назад

Who is here in 2024😂👌

@zahraanajah5590 3 года назад

Oh my god, I love you ❤❤❤. You saved me 😭 thank you sooooo much 💘💘

@johnfrancis_kennedy 3 года назад

Fantastic content. You're helping me and so many others out with your videos!

@ChoolweO Год назад

7:58 COX1, COX2 😂 "Keep your minds clear it's a Cycloxygenase."

@sirinesaleh5398 3 года назад

Hello ninja nerd, first thank you so much for your videos they saved my life. Can you make more immunology videos, because a vast subject, and i think many people, other than me need them ( cytokines and chemokines, Dendritic cells, MHC, B-cells development, immunological synapse). Thank you deserve so much more recognition.

@esvittie8515 Год назад

hi! is it prekallikrein ??

@mohsinfareed1797 3 года назад

LONG TIME I STOPPED USING RU-vid FOR ANYTHING EXCEPT WATCHING YOUR WONDERFUL VIDEOS. THANKS VERY MUCH FOR MAKING OUR LIFE SO EASY.

@Alexandraa.18 10 месяцев назад

Subtitles pleaseeee!!

@knasttrast7168 5 лет назад

The thing you called margination is in fact rolling. Margination is the process in which the blood cells moves from the center to the sides of the blood vessel (due to vasodilatation slowing the blood flow) and that happens before rolling.

@mikkeladamsen8380 2 года назад

Great video, thanks! I just have a question. So im doing some homework and it revolves around how chronic inflammation can be the cause of cancer. So im wondering if its just as simple as to say, that mitosis is required in a certain amount due to the reparation of the damaged cell tissue. And therefore with a higher amount of mitosis taking place, the risk of a mutation is present.