IMPORTANT QUESTIONS| Hospital And Clinical Pharmacy| D Pharmacy 2nd Year| Ch-11 (Pharmacovigilance) 

IMPORTANT QUESTIONS| Hospital And Clinical Pharmacy| D Pharmacy 2nd Year| Ch-11 (Pharmacovigilance)
Hospital And Clinical Pharmacy Important Questions Series 👇👇👇👇
Hospital And Clinical Pharmacy D Pharmacy 2nd Year: • Hospital And Clinical ...
Pharmacovigilance refers to the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects and other drug-related safety problems. Related to this general definition, the underlying objectives of pharmacovigilance are to prevent harm from adverse reactions in humans that arise from the use of health products within or outside the terms of marketing authorization and in relation to the life cycle of these health products.
The main goal of pharmacovigilance is thus to promote the safe and effective use of health products, in particular by providing timely information about the safety of health products to patients, health-care professionals, and the public. Pharmacovigilance is therefore an activity contributing to the protection of patients and maintaining public health.
Many other issues are also of relevance to pharmacovigilance-related activities and include medication errors, lack of efficacy reports, off-label use, acute and chronic poisoning, assessment of drug-related mortality, abuse and misuse of health products, and adverse interactions of medicines with chemicals and other drugs.
The pharmacovigilance approach can be clinical, epidemiological, experimental (e.g., to reproduce an adverse effect in animals to better understand the mechanism involved for human protection), or diagnostic (e.g., imputable methods).
The ultimate goal of pharmacovigilance is to accurately characterize and optimize the benefit/risk ratio of a health product throughout its life cycle.
Pharmacovigilance in developing countries
National pharmacovigilance systems/programs have been launched in 20 countries out of the 21 included countries. The first national pharmacovigilance system/program was launched in Burkina Faso in 1977 and the first country to join the WHO Program for International Drug Monitoring was Thailand in 1984. However, there are many challenges facing PV, including underreporting of suspected adverse drug reactions (ADRs), lack of pharmacovigilance programs in the hospitals, lack of awareness of PV, lack of knowledge of ADRs and their reporting, lack of human resources, lack of funds and financial support, and lack of research into PV-related issues. summarizes the characteristics/challenges of PV in the 21 countries.
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