Is There Hope For The Future of MS Care? July, 2023 

Omg!! This is what I’ve been so confused about. My doctor makes me feel like if I have no new spots then I “should be fine”. I feel so validated. Thank you for posting this ❤️🙏🏼

I like how you break it down so the non medical people can understand it. You communicate really well. I bet your patients really appreciate that.

Hi, Aaron. Thanks for all that you do for MS sufferers. As a psychiatrist, I have clinical interest in this topic and as a husband, my wife is impacted by MS as well. Not only do you provide wonderful insights to your patients, but your approach and communication skills have taught me a lot about patient education as well. Keep up the good work!

I just recently discovered your channel. I was diagnosed last year with PPMS. I visited NIH in Bethesda MD in November for a study they were doing. I am 56 and have had some back issues , life as a pipe fitter. So pain was always an issue . Long story as to how MS even came about. Absolutely love your channel. I watched most of your live stream and was able to watch this one. I am in SC and for a better word,3-4 hours away from any good care. I just recently started checking out MS videos here on RU-vid,I promised my wife I’d stay away from them. I’m going to have her watch some with me. Thank goodness for the ability to be able to access these! Great work and looking forward to more from you!

Being someone who has MS vs. someone who treats MS, I would add a thing and hope for a second. I watched a video from Dr. Beaber's channel that showed data that indicated not only a link, but to me, an almost causal relationship with EB virus and Mono and MS. To me, that is flying under the radar because if MS is caused in large part by Mono, effective and safe vaccines would totally be a game changer. Lastly, being advanced in my disease progression, re-myelination therapies are the only thing that would make me truly hopeful for my quality of life and while there is research ongoing, so far, there are no therapies I'm aware of. BTW Dr. Boster, your channel was a huge game changer for me! My ability to navigate my situation improved beyond expression when I found you! Thank you!!!

It is so cool having a great doctor speak on such a normal person level. You do a great job of explaining complex concepts in an easy to understand way. Thanks for all you do and especially these videos. They help me understand my daughter's issues a lot.

Thanks Dr. Boster! It is so nice to see you excited for the future of MS and its treatment.

Thank you so much for this! It's always been confusing and angering to me that my neurologist acts like like if there's no new lesions then yay, party, as if my slow, life impacting, soul crushing deterioration isn't even happening. It feels like anything about new lesions medicine listens to and everything else I'm on my own.

At last I’m not going mad! Great topic delivered as usual, clearly and practically. Let’s hope this understanding is widely adopted

Thanks for discussing "smoldering. " I've always felt like, despite that I don't/haven't ever had noticeable relapses, MS has just been smoldering in me.

Great info! My neuro has mentioned Smoldering Lesions for years, and most recently I’m putting two & two together: Since I’ve been on Ocrevus (5 yrs), I’ve improved a lot! I’m still disabled, but I no longer need the daily use of a rollator or cane, and my cog function has improved a bit. I’m guessing that the Ocrevus keeps the smoldering down and is why I feel better. This drug changed my life! 🙏

Love the concept of a neurofilament light chain blood test. Sounds great :)

I’m glad he addressed the no new lesions situation. You can progress without new lesions. True facts. Some doctors just suck. He’s good

Thank you Dr. for your constant updates, and shedding light on MS. I feel I have a RU-vid neurologist i can get guidance from 🙏 💛

Dr. Boster, Bones McCoy has nothing on you :). Missed your go-live Sunday 7/9/23 but watched the replay. Congratulations on 50K. While I watch, I read some comments, AMAZING the impact, hope, and clarity you are providing to people impacted by MS. I don't know much about the snap chat filters but I love that you do them to have fun. It humanizes you as a Dr. , makes the info less intimidating, and what I get out of it is that even with MS it is important to have fun. Thank you.

Thank you for the hope. I am a support person.

Thank you for this - the talk of paradigm shift is very powerful. It feels to be a move towards treating the whole person and whole lived expe rience of MS. The best care I've had here in the UK has always reflected this. The most powerful question for me has often been " What else is going on with you...?"

Thank you for this info, Dr. Boster. I keep up to date on your videos to stay informed. Much gratitude for sharing here. I often think your patients are so lucky to have you, but we all get to experience you too though! 🙏🏻

This is for me. Thank you! PPMS on Ocrevus, slowly getting worse. Actually not so slowly. It isn't all about the lesions.

I'm the classical PIRA patient. Thank you for your videos and live streams. You're the best!

Congratulations on reaching 50K followers 🎉

Hey Doctor B. Another great video with a lot to think about. You have given me so much info about MS and my MS. Thank you so very much.

Thank you Dr.B! For talking about this!❤

Thanks Dr. For the update 😊

Thank you for taking the time to make your videos - you have been a refreshing clarity in all the “noise” out there about MS. While I am learning, there is also so much optimism in the future of MS research and treatment. Thank you so much.

Good morning Dr.B recently had surgery on my lower back for pench nerve i feel way better no pain in walking i feel the best i ever felt in years

Dr B... you're awesome. I appreciate your enthusiasm and the..."dumbed down" explanations you share wo being condescending. 🥰

Thank you dr, B. on these valuable infos !

Wow I have been binge watching you as I just found your channel 👍. My son is 48 and has aggressive MS. It took 9 months to see a specialist and 19 more months to get his first treatment here in Ontario. He has had it for a long time but didn't realize it was MS. He is progressing very rapidly. If anyone has anything to offer for help please let me know. I have learned so much from reading the peoples comments as well. Does anyone in Ontario know where to get a cooling vest? Thanks in advance. Thank you doctor for all your help and hard work you do for us.❤

You say you’re very excited you do look excited

Yep. I’ve been waiting for this.

Thanks for discussing the NfL chains! My neuro recently drew that and I wasn’t sure what it was. I was able to find literature on it but found varying info on what is considered normal. Mine turned out fairly low so good news!

Hey doctor! I learn ms with you! ❤ there is always hope for a better future.

Dr. Boster, you're great! Your videos were mentioned by my neurologist at Mt. Sinai in NYC. Keep up the great work.

Thanks Dr Boster again another very informative workshop. Looking forward to more.

Great Video!!! thank you, Dr. Boster!!!

Great news, thanks Dr. B! I'm excited about BTK inhibitors as well. I'm currently on Ocrevus and hoping to regain my full immune system.

Love your videos! I'm from Brazil. I was diagnosed last year with RRMS and start treating it with Tysabri, but going to change it to Lemtrada in september. I hope to stop MS until realy good treatments to come avilable in the next years. Thanks for your amazing work on bring information with quality and simplicity on your channel.

I’m so excited about all these things and they can’t come fast enough!

Wow. Thank you. I have felt the very SLOW slide since my diagnosis in 2003. MRI's clean...

I love how Dr boster keeps us informed of the new treatments that are here and are coming. I just can't wait for the new therapies to help us. I can't wait to hear more of the BTK INHIBITORS. sounds very exciting to hear such a thing that's coming. Just waiting patiently for new horizons.

Thank you for the Monday morning video seen in the afternoon. As a smoldering kind of guy I am excited about the new developments that you described. Doug coffee in hand from Lyndhurst Ohio.

This is very exciting news. Thank you for sharing, and caring!

Thank you for this.

Thank you Dr. Boster for this information.

Thank you for this informative message Sir Aaron

That is another fantastic video, Aaron. I love how you define BTK inhibitors, which is very exciting. I've been trying to read up on this, but after your explanation, I understand it much better. Thanks so much.

Thank you so much for your channel! It helps me more than every single vistit to my Neurologist…….

So late to the party but you know I will never forget to watch a morning Monday episode ❤🔥 Dr.B 🇨🇦🇨🇦 Nancy

Thank you from Liverpool 🇬🇧

Thanks doc for this info and all you do.

Thanks doc!!

Thanks for the update.

So glad and optimistic about participating in Gemini 1! In fact, I was looking deeper into it just last night. Are there any phase 3 results available to read just yet? Congrats on 50k! 🎉

DR B. this was a great video, your method of instructing is so down to earth. They often validate some of the issues I have been experiencing. Thank you so much for your clear concise education of the many issues we experience with MS.

Hi Dr. Aaron have you also looked at Alpha Lipoic Acid research? (dramatically reduces brain shrinkage by 60-70% in a 2 year study) One thing I am surprised by is that brain volume is not really monitored, at least not at my neurology department. I think brain volume is a major component missing from treatment plans currently, perhaps also linked to smoldering MS. MRI may show new spots but the damage present may be exacerbating by less "brain resources" available to compensate due to shrinkage. Interested to hear if you have software that looks at this or suggest other supplements that may help slow down this shrinkage. * From some studies brain shrinkage is 5* higher than in a regular individual. Every year is almost equivalent to 5 YEARS of a normal individual, this scares me quite a bit. Specific LA study: Lipoic acid in secondary progressive MS: A randomized controlled pilot trial

You rock !! Let's hope that more Doctors like you, Gavin Geovanonni, my doc (João Cerqueira) and others can shift the way MS is treated from onset 💪💪💪 #mswarrior

This channel has amazing information. 👏

You’re a very great orator, you really giving people like me HOPE! God bless you.

I laughed out loud when you were biting on the cord,😅 You have a great teaching style and I appreciate it.

Just discovered you today 9/10/23, im subscribing! Thank you, thank you, thank you🙌🏾

Thanks Doc

This is what gets asked so much in fb ms groups im in - pira. Thanks for explaining it.

New Brunswick Canada AT LAST SOMEONE GOT IT RIGHT❤❤❤ 64 F MS diagnosed 7 yrs😅 ago . MS since at least 1997 Bless your heart

Another really interesting video, Dr. Aaron. I've just added you to my team by subscribing.

As a type 1 diabetic for 30 years, also diagnosed with Charcot Marie Tooth disease for the last 12 years, and as of two years ago MS, this really sparks hope in me Aaron, my MS doctor is great and I appreciate him BUT your comment on purely focusing on no new lesions NOT individual patient needs hits home for me because that is my current struggle. sure my lesions have faded and only a few small new ones have surfaced and that’s great and I’m thankful but what about all of the rest of my issues from MS, I understand I am only 2 years in to my MS journey but I am no stranger to only treating one problem at a time or at all. We need more docs like you who care more about individuals and their unique symptoms and struggles. I understand there are a lot of terrible health concerns diseases and people out there who are worse off than I am but it is nice to know that one of my conditions is being researched beyond slapping a bandaid on it and calling it good.

Hello from Israel great hope for my daughter that was diagnosed this year and is on TYSABRI

I am so glad you posted this I was just discharged from the hospital yesterday because they said I was fine no new lesions but I'm not fine symptoms are so unmanageable waiting to see neurology the end of August any suggestions thanks in advance...

This is a GREAT video. My MS hasn't followed the "textbook" course so I'm always looking for answers.

I completely agree ❤ I had a hard attack last year (I was on Mavenclad, now just finished Lemtrada and I was diagnosed in 2020) and I changed my habits to change my prognosis. I started strengh working out, eating antiflammatory food (eliminating gluten and diary) taking vitamin D. Doing this we can control the progression. As a chemist, I learned so much this year on diseases and convencional medicine needs functional medicine. A huge hug doctor. Thanks for your videos.

Thank you Dr Boster excellent video! Love the Bones impression 😂🔥🔥🔥🔥🔥

Excellent videos Dr Aaron. I was diagnosed with Rheumatoid Arthritis a year ago. My Rheumatologist spoke to me on the telephone asking me about how I felt etc. I live in the UK so the health service is strugglig under pressure these days. I told him that I was siffering from tinlgling in hands and feet. That was in March. He contacted my GP who tested me for B12 and folated defieciency. They were fine. They referred me to a Neurologist. He reported "He walked normally but had a slight sway on Romberg’s test. The upper limb reflexes were just present, but the lower limb reflexes were all absent and there was subtle patchy reduced pinprick sensation in the feet up to the mid shin levels. There was no evidence of weakness and dorsal column function was intact. I note that you have kindly sent a battery of blood tests for neuropathy screen but I wonder if I had received them all. His Vitamin B12 and folate levels, basic biochemistry and full blood count were all normal. He told me that his glucose level was normal, but I could not see this. Please would you be kind enough to ensure that he has also had Igs / electrophoresis, ANA, HIV test, and ENA screen (for Sjogren’s), although I presume that these may have already been checked when he had his rheumatology appointment." He also stated " He also has a history of bladder symptoms with urgency and difficulty voiding for which he has been under the care of the urologists." And also, "Over the past few months he has reported dry eyes, but of course he has been on the Amitriptyline. He does not report any systemic or constitutional features." I had a nerve conduction study which came back as normal. He wants to see me gain in 4 months.....in October by now. I guess he doesn't suspect MS as he hasn't sent me for an MRI?

Very, very, very exciting! I have secondary progressive and I’ve been asking for a DMT (I’m on none as we speak, too many serious reactions) and my Neuro has been putting it off as I’m assuming he’s waiting for some new DMT …. I’m seeing him in February- we will see!

Wow ! Thanks

Also my Dr he test NFL, and you explain it so well ty.

These BTK inhibitors sound like a potential game changer. 🙏🏼thank you as always Dr B

This is so interesting and hope this nfl testing comes soon.

Thank you soo much doctor. May ALLAH guide and keep u healthy to find a treatment to overcome and cure MS.

Hello from Australia Dr Boater

Ty! That is me I'm seeing in your words. I was diagnosed 2018, with numerus lesions, and was put on interferon 6 months after the MR. New lesions stopped, but I feel heavy cognitive cognitive problems and things are getting wors, but no new spots and I am even able to walk 🙄 Well now... I asked codnitive testings and asked doctor that will look at last MR I did few days ago to look at brain deterioration carefully because I have conditions that are on "promo pages" of starting of Alzhaimer 😅 😢

Very interesting! Looking forward to your video about MS and menopause.

Question for Aaron Boster, have you heard of topical insulin eye drops? Insulin eye drop is an old treatment for repairing injury to the cornea and is sometime used ‘off licence’ for the treatment of eye ulcers. Recent research into treatments for glaucoma has shown that six weeks of Insulin eye drops can repair/restored damage to the optic eye caused by glaucoma. Insulin eye drops could be a potential treatment for damaged to the optic nerve caused by optic neuritis in MS. Insulin eye drops may also help to repair MS lesions at the front of the brain because Insulin is able to pass through the blood brain barrier. Love to see a future video on this topic to get your thoughts on this potential treatment.

Great video. I'm watching right before I see my Neurologist to be better prepared. Can you please add time markers to your videos, and can you link to these topics in your comments? For example, I had to rewind your video and look up BTK inhibitors. If there's an article you like about the topic, can you please drop it in the comments? Thanks!

By the way: your home looks beautiful 😊

Neuro filament light testing sounds great but the Veterans Administration is averaging about 30 years behind the time. I find myself asking questions that the doctors are either unable or unwilling to answer. The latter sounds malicious (or incompetent) so I lean towards ignorance about the topic and an unwillingness to say “I don’t know “ because ego gets wounded. I don’t expect my doctor to know everything. That’s unrealistic. But I do expect honesty and a willingness to acknowledge that the question exceeds the doctors knowledge base.

Thank you above all for your optimism. It's not directly related to my MS, but I think a lot about singer Freddie Mercury, who was diagnosed with HIV in 1987, suffered terribly, and was dead by November 1994. I think also of basketballer Magic Johnson, who was diagnosed with HIV in November 1994, the same time Freddie died-and almost three decades later, he's still alive and well. This is something I think of a lot as someone diagnosed with MS in 2022. I no longer care too much about whether we ever find a "cure" for MS in the way we can cure measles or malaria. I think we fixate too hard on how scary a word "incurable" is, when we are making such big strides toward keeping the disease in check for longer and longer periods, with fewer and milder relapses, less PIRA, and better quality of life. A year and a half in, I've achieved NEDA-3, and my neurologist says, "all we have to do is keep you here for another 70 years." I don't think I'll be here past 100, but I really do feel like a life of high-function is more reachable now than it was even a decade ago. It's a good time to be hopeful.

Hello Dr. Boster, we MS international community need your help. Please talk about Marc Abreu a "doctor" who in Florida makes claims that with his thermic treatment he can cure Parkinson, Alzheimer and MS. It's not drama, it's dangerous! The treatment costs a lot of money and is especially promoted to Brasilians! MS community of brasil needs your help Dr Boster! Greets from Paris

Fascinating, I'd very much prefer a blood test rather than an MRI with similar clinical reliability in MS. Then if the test is high confirm with an MRI. BTK inhibitors are fascinating but I'm pleased enough with Lemtrada for now. For the right candidate it is definitely the easiest Drug to deal with if you don't have any major complications.

Dr. Boster, I love listening to your videos. I'm having such a difficult time understanding menu planning at home. I'm trying to cook, and I end up wasting food because I didn't prepare it correctly OR because the half used packaging of ingredients isn't used because I don't know what to make with it. I hate being a burden. It's what I feel like I've been reduced to, though. Please, if your facility deals with these types of issues with MS patients, could you put a link in your videos to sensible recipes or menu plans? I don't know what to do here. I've gone from being a sandwich, fast food eating, industrial electrician to a haphazard housewife.... I only know how to cook comfort foods, 5 things only fluffy girls like really. Or, I know how to order pizza and cheeseburges... I can actually do that without burning it.

Dude, Bones McCoy is my favorite ST character.

I have SELs at year 3 of MS x)

Could you please do a video on aHSCT for those contemplating getting on the waiting list for this treatment. Pros and cons and a detailed explanation. Many Thanks in Advance

Its trial and error. Example my dad went thru hell to finally find he had ms and now its a spinel tap and mri. Amen 😎 👍

Doc, you give me hope. I was diagnosed in 2021, after a year and a half of symptoms but minimal mri evidence. I am on DMTs of course, but not in remission yet, unfortunately. But you give me hope that this thing might get better in the near future & i could have a normal-ish life ❤

Can you make a video on CIS please - would you put someone on high efficiency drugs first off - or ones from 1990 ? Ty

I was diagnosed with RIS in March. I have absolutely no symptoms. I've had 3t and 7t MRIs. A colleague of yours is my neurologist and I'm dancing around the idea of doing 2 years of Ocrevus but my quality of life is great and don't want to become immunocompromised, especially being an ER nurse. Can you give any advice or do a video on starting DMTs for RIS? Thanks!

Holy cow....missed ya again. Ugh

Did your dragons become plants, that's cool, I need some of those.🔥🔥🐲🐉

I'd do anything to walk again.