Ketamine Therapy: Does it Work?

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Interest in ketamine therapy has jumped off since its rapid-acting antidepressant effects were first discovered. The therapy has been a huge boon for people with treatment-resistant depression, or folks who’ve tried all kinds of typical antidepressant treatments with no luck. But is ketamine therapy right for you? And what should we make of the rapidly growing ketamine telehealth industry? Vitals host Alok Patel answers all your questions and more, with the help of Dr. Gerard Sanacora of the Yale Depression Research Program and Dr. Hannah McLane, a ketamine-assisted therapy provider.
🩺🥼 Vitals is a series that’s taking a new approach to health and medicine. Hosts Alok Patel, MD, and Sheena Williams RN are going beyond the headlines to answer your questions on the latest health topics. No judgment, no taboos. Just 100% science-based information.
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Find our experts and hosts:
:: Sheena William, RN ::
Twitter: @Keepingitkinky1
Instagram: @keepingitkinky
:: Alok Patel, MD ::
Website: alokpatelmd.com/
Twitter: @AlokPatelMD
Instagram: @alokpatelmd
:: Hannah McLane, MD MPH::
Instagram: @drhannah.io
Website: soundmind.center/drhannah
:: Gerard Sanacora, MD PhD::
Professor of Psychology, Yale School of Medicine; Director, Yale Depression Research Program.
The exact mechanisms by which ketamine interacts with the neurotransmitter glutamate are not fully understood. To learn more, check out the following article: www.nature.com/articles/s41380-021-01246-3
To learn more about ketamine therapy:
- www.cambridge.org/core/journals/bjpsych-open/article/ketamine-for-the-treatment-of-mental-health-and-substance-use-disorders-comprehensive-systematic-review/36E261BFA62CDA6459B88F7777415FDA
- www.smithsonianmag.com/science-nature/a-brief-history-of-ketamines-use-to-treat-depression-180980106/
- www.nytimes.com/2023/02/20/us/ketamine-telemedicine.html
- www.webmd.com/depression/features/what-does-ketamine-do-your-brain
This episode of Vitals is licensed exclusively to RU-vid.
00:00 What is ketamine therapy?
02:03 How it works: what we know
03:00 Who's it for?
03:27 Esketamine vs. Ketamine
04:31 Off-label ketamine therapy
05:09 Ketamine via telemedicine?
06:54 Ketamine uses under study?
07:49 Ketamine-assisted psychotherapy

Опубликовано:

27 апр 2023

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Комментарии : 64

@priddyting 9 месяцев назад

I suffer from bipolar depression, anxiety and PTSD. I started ketamine IV therapy last week I've had three treatments total and it has been such a positive experience for me. My doctor does not recommend the oral or nose spray. I made sure to research many of the doctors in my area before I chose the clinic to go to so the doctor that you end up with and the environment that they provide makes a huge difference on your experience. I have been on and off of SSRIs for the last 15 years and all of them made things worse rather than better. I'm never going to take another SSRI again as I am one of those people that is considered treatment resistant. So ketamine has been such a blessing and I highly recommend the treatments. But again do your research go and get free consultations and make sure that you find a doctor that you feel comfortable with. Best of luck to everybody out there who's suffering because I know all too well what it's like ❤

@Ktoppers 8 месяцев назад

People with bipolar depression should never be on SSRIs by themselves anyway. Have you talked to your doctor about other medications?

@priddyting Месяц назад

@@Ktoppers sorry for my delayed reply I've had my notifications turned off on. I'm intrigued by what you said about bipolar and SSRIs. I am yet to find a good psychiatrist been to several and have been diagnosed multiple things. It's utterly exhausting dealing with mental illness, anxiety and PTSD. I haven't had a ketamine appointment since last November and I'm still struggling with my mental health (and alcoholism which runs in my family and oh so often goes hand in hand with mental illness) 😞 anyway I'm always open to insight and information to help myself and educate myself because none of these doctors have been able to 😆

@ellafanger9239 Год назад

really informative on a fascinating topic! thank you!

@Nan-59 Год назад

Good topic! Thanks ❤❤❤❤✌🏻

@MrBibi86 Год назад

*You better have a briefcase full of cash tho. here in Australia, there is a place that does Ketamine infusions but at the cost of $150, an infusion is recommended for 18 treatments. After taking antidepressants after antidepressants with no positive effects for 16 years this treatment could probably help me but I don't have the money*

@JenLovesPizza 11 месяцев назад

It’s 400 a treatment here in the US. And they recommend 6 treatments.

@umamifan 9 месяцев назад

It depends on a variety of factors, like what state, what insurance, what provider, what treatment type since there's multiple kinds of ketamine therapies, etc. it can cost more, less, or even be free depending on the factors, so idk if it's accurate to say "In the US" when it varies.@@JenLovesPizza

@wolfvision47 6 месяцев назад

Which place in Australia pls.

@denisedobson2007 6 месяцев назад

It is $850 per infusion with a 6 week program. Saw immediate results with my TRD daughter-amazing.

@denisedobson2007 6 месяцев назад

In Canada-sorry-forgot to add to post.

@kristinat8298 3 месяца назад

PTSD here. I did the IV infusions. I had 4 infusions already and it has been a life saver for me! I have 2 more left. But the key is to have therapy right after your trip.

@thepeff Год назад

I’m bipolar and have very few treatments available to treat my depression because antidepressants could cause mania. My doctor recommended NAC and B vitamins and that was a night and day difference

@Greatbliss-mv7ue Год назад

I WILL NEVER FORGET HOW I OVERCAME MY NASTY BIPOLAR DISORDER, I USED DIFFERENT MEDICATIONS BUT NONE WORKED, I WAS LUCKY ENOUGH TO HAVE COME ACROSS DR OKOUROMI ON RU-vid WHOSE HERBAL MEDICATION FINALLY HELPED ME TO GET RID OFF IT COMPLETELY. IT HAS BEEN 4 MONTHS NOW AND I HAVEN'T EXPERIENCE ANY SIGN OF BIPOLAR DISORDER AND I'M COMPLETELY GREATFUL FOR THAT. #DROKOUROMI.

@suzannek3493 Год назад

what is NAC ?

@thepeff Год назад

@@suzannek3493 n-Acetyl l-Cysteine

@miggs80 9 месяцев назад

Do you have bipolar or depression? They’re entirely two different things.

@tjancijr 8 месяцев назад

@@miggs80 All due respect, nobody is 100% any single "disorder". Shades of gray.

@srivalli6965 29 дней назад

After narcissistic abuse i was recommended this because the abuse gave me PTSD. I hope it works

@AnastasiiaDemishkevych 29 дней назад

That's why you need a specialist who will guid you well on it before taking.. I'll recommend you to this dude who has been my guid he got all kind of psychedelic products he also will guide you how to make proper use of it he can ship directly to any location

@AnastasiiaDemishkevych 29 дней назад

Dude as mycotinny

@AnastasiiaDemishkevych 29 дней назад

On Instagram

@safaiaryu12 Год назад

Been very curious about this. I have had chronic pain my whole life (juvenile arthritis that developed into adult arthritis, stage IV endometriosis, fibromyalgia) and depression, anxiety, and PTSD directly related to the chronic pain. I've been told ketamine can help with ALL of these. But I've also heard bad stories - you highlighted someone for whom it didn't work, and the expense is atrocious. Besides, my pain doctor considers it an "extreme" treatment and won't approve it for my relatively low-grade daily pain levels (nevermind the excruciating spikes that sometimes land me in the ER). Her opinion kind of puts me off of the idea. But man, one treatment that covers a number of my different debilitating conditions? It does appeal...

@deetlebee Год назад

While spravato didn't cure my depression, while I was on it it helped my chronic spine pain. (I have nerve damage from multiple herniated discs/discectomies). I have a spinal-cord-stimulator and I was able to turn it WAY down during treatment and for about 48 hours. It wasn't a pain cure for me. But it it was a pleasant surprise.

@bumblebee5990 Год назад

It will work for FM, PTSD, anxiety. To be honest, I hardly have any FM pain anymore and a chronic pain has completely disappeared. Not having as much pain gives you space to handle the emotional aspects. If you give it a chance it might work for you, if it doesn’t you will know within a few treatments. Most clinics, also will customize your cocktail, you can get some Tordall or magnesium (which extends the effectiveness) I hope you find relief and peace.

@C_Hart 8 месяцев назад

This treatment would be almost perfect for you imho but then again I'm no doctor and I don't know your pains exactly. I am going on my 4th infusion next Tuesday. I have ptsd from getting hit by the lite rail train in Minneapolis. Im Bi-polar and have treatment resistant depression. If your doctor thinks it's extreme Shea somewhat right but it's becoming more main stream. I'd suggest maybe getting a new primary doc but honestly I'm not sure they even need to sign off on it. All I did was call the clinic got a consult, explained my conditions and then they scheduled me. Idk maybe my clinic "The remedy" is just efficient ? Whatever the case if I were you I'd Google ketamine in your area and see if they can line ya up. You won't regret it. It's like feeling sun on your soul for the first time.

@vocals1111 2 месяца назад

@@deetlebee did u do infusions at all or only the spray and who prescribed for you, pain Dr or Psychiatrist? Also are u able to administer that urself and how expensive. Sorry for all the Q's

@deetlebee Год назад

I unfortunately fell into the 20% of folks spravato didn't work for...I tried for 3 months doing 2-times-a-week. I had some relief for a few days, but since it involved an entire afternoon off of work, I was unable to keep trying to get it to stick. :(

@pbsvitals Год назад

Thanks for sharing. It always tough when something doesn't work out. Have you found anything that works better for you?

@deetlebee Год назад

@@pbsvitals Not yet. But thanks to this video I learned about the possibility of telemed ketamine, which with my psychiatrist's oversight I think I'll pursue. So thank you for informing me of another possible avenue of relief!

@safaiaryu12 Год назад

Such a deepseated problem that work environments can't accommodate health treatments. I'm super lucky that I work from home and can set my own schedule, so doctor's appointments generally aren't a problem for me, but there are so few people for whom that is the case. Even if you can mess with your schedule, missing hours might mean a smaller paycheck, which just isn't feasible for so many, especially the chronically ill. Do better, America.

@vocals1111 2 месяца назад

How expensive is spravato?

@bumblebee5990 Год назад

This does work for many people. It is fantastic for pain, including phantom pain, the MS studies are so promising. Definitely go with the infusions as they are more effective. It is safe for most people. A good clinic is worth the money. The nasal is all about profit and not about the patient, the IV infusions are the best, you can always shut off the drip. Insurance does cover some portion of infusions, but not enough to make it availability. The rate increases in blood pressure, and heart rate only occur during the infusion. It is cleared for PTSD and does work, it does work for anxiety. I highly recommend IV infusion treatment. I personally feel it should be made available to veterans and first responders. Average cost for an infusion in America is 600$. Standard start is six sessions. Then boosters when you feel you need them. That’s right, you get control, which could be the most effective part of treatment.

@bumblebee5990 10 месяцев назад

I am glad you found it helpful.@Sandrabill252

@bumblebee5990 10 месяцев назад

@Sandrabill252 you were mailed I’ve bags and then self administered, that is new to me, it’s amazing what you can get online these days.

@vocals1111 2 месяца назад

I sure hope it works for extreme pain as it's my last resort.

@bumblebee5990 2 месяца назад

@@vocals1111 I will hold positive thoughts for you.

@vocals1111 2 месяца назад

@@bumblebee5990 Thx very much. Can u tell me what part was covered by insurance? My pain Doc offered to me 300 a session so that seems reasonable. I have extreme pain from 14 back surgeries and losing my pain pump to infection. Also recently developed terrible anxiety, anger and nerve pain in feet so hoping it helps 1 or more of those at least.

@andrewmeitner4818 10 месяцев назад

Works for me for the last 7 years!

@vocals1111 2 месяца назад

Hi, how many treatments did u start with and how often after 1st series did u feel u needed more for maintenance dose

@andrewmeitner4818 2 месяца назад

@@vocals1111 I started with 6 treatments in 2weeks. I get about 8 treatments per year for the last 7 years. Ketamine infusions are extremely enjoyable for me

@andrewmeitner4818 2 месяца назад

@@vocals1111 I started with 6 infusions in 2 weeks. Depression was gone after 2nd infusions. I do about 8 infusions a year and have done infusions for about 7 years. Depression has come back a couple of times and then I will shorten the time between infusions

@ahjgbhlahgaohgl Год назад

The audio in this episode is pretty bad

@pbsvitals Год назад

Sorry! There is room to improve for sure.

@princeamu 3 месяца назад

Really?!? Sounds good to me

@ThatTaRaGiRL 4 месяца назад

Climate change anxiety!? I say this with the deepest respect...but we CAN do something about it!! I see SOA MANY people complaining about it yet, do NOTHING to contribute! And for those ones- DEAL with your anxiety! Because if you have enough brakn cells to be anxious about it, then you KNOW BETTER and can't just use some "ignorance card" to dip out of the lack of responsibility! For anyone that DOES contribute- THANK YOU and together we will nail this! Keeping our kids involved will also give them the same passion and carry down the good habits 💚

@RavenFilms Год назад

Why is he yelling in a room. It reminds me of 2010 RU-vid.

@matovicmmilan 9 месяцев назад

What do you mean 2010 RU-vid?

@Watch-0w1 Год назад

Why seek cure with pill for mental issue? Y not ask why this a trend ? Be careful with bad player looking to profit out people. Better find reason why this happening to so much people

@chris4charity191 Год назад

Holy poo ... Work on Yourself! Depression, anxiety worsen PTSD and chronic pain. Realise and process your traumas and only then will you heal. 8 years on SSRIs and I came off them a year ago after 5 years of self discovery. It wasn't easy, still some days are difficult but don't dwell in pity. Get up, work on yourself and your feelings and heal. Tip for beginners. Look at your childhood.

@Ketamineintegrationcoach Год назад

Thats what ketamine infusion is. A time you can look at your trauma and reasons behind your mental illness. You fight your mental illness during the infusion. I have been getting them for 7 years. I get them twice a year now. Ive lived in remission for 6 years'