Lac (Lactose) Operon, Trp (Tryptophan) operon…Control of gene expression in Prokaryotes. Lac stands for lactose…When it comes to bacteria (e.g. E. coli), the favorite source of energy for metabolism is glucose, but what if glucose is lacking in the environment? -Then, the bacteria will use an operator (operon) to switch to lactose (lac) metabolism…Lactase enzyme digests lactose into glucose and galactose. An operon is a group of genes clustering together on one chromosome and sharing one promotor. You need to know about the regulator, promotor, operator, repressor, co-repressor, catabolite activator protein (CAP), and structural genes of the lac operon. The lac operon is a negative, INDUCIBLE system, whereas the trp operon is a negative REPRESSIBLE system. What’s the difference between negative control and positive control?
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