Lady with an Ermine: The Setter of Mysterious Portraiture 

Painted a decade before the Mona Lisa, the 'Lady with an Ermine' is the portrait of Ludovico’s mystress Cecilia, Leonardo’s patron for over 18 years.
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Artworks featured:
Leonardo da Vinci:
Lady with an Ermine (1489-1490), Czartoryski Museum.
Ginevra de' Benci (c. 1474-1478), National Gallery of Art, Washington D.C.
La belle ferronnière (1490s), Louvre Museum.
Mona Lisa (c. 1503-1506), Louvre Museum.
Giovanni Ambrogio de Predis, Portrait of Ludovico Sforza (late 15th century), Castle Trivulzio Library.