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Lipid-lowering medications: Fibrates ~Pharmacology~ 

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What are fibrates? Fibrates are a group of lipid-lowering medications, along with statins and niacin. These medications are very effective at lowering triglyceride levels in the blood, but are less effective at controlling cholesterol.
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29 сен 2024

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Комментарии : 8   
@muhammadyahya110
@muhammadyahya110 7 дней назад
That ending sound ----> ❤
@kryptonite3846
@kryptonite3846 8 дней назад
Very informative. Thank you❤
@osmosis
@osmosis 5 дней назад
Most welcome! 💕
@WhyNot-si4pj
@WhyNot-si4pj 7 дней назад
4:10 Increasing the activity of lipoprotein lipase enzyme (LPL) in the blood capillaries supplying the adipose tissue results in LOWERING serum triglycerides (TGs) . This is achieved through the hydrolysis of the serum triglycerides present in the chylomicrons & the very low density lipoproteins (VLDL) to fatty acids & glycerol , then they are taken up by the adipose tissue to be re- esterified back to triglycerides & stored in the adipose tissue . The net result is the shift of triglycerides (TGs) from blood towards the adipose tissue . While the fatty acids reaching the liver will be directed towards the beta - oxidation pathway of fatty acids in the mitochondrial matrix - enhanced by the fibrates - to be broken down to generate acetyl coA ; instead of getting re- esterified back to triglycerides & released to the circulation in the form of very low density lipoproteins (VLDL) .
@aasemahsan
@aasemahsan 5 дней назад
3:36 Fibrates Activates PPARα Increased LPL Increased beta oxidation Increased HDL synthesis
@HagerAlsqaf
@HagerAlsqaf 8 дней назад
Thanks ❤️
@osmosis
@osmosis 5 дней назад
You're welcome! 😊
@aishanadia7289
@aishanadia7289 8 дней назад
Wow❤
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