Liver Explained Clearly - Pathophysiology, LFTs, Hepatic Diseases 

See the whole series at www.medcram.com along with other top quality videos including reviews in pulmonary, cardiology, infectious disease, and hematology!

Dr. Seheult - Your videos have helped me a great deal while in FNP school. I greatly appreciate all the time and effort you put into these videos to break the larger concepts down into something manageable. Thank you so much.

You make it all easier to understand... well explained and not rushed. Also you have a nice voice...calm and nicely paced which I think helps when learning. Much appreciated, thanks :-)

Thank you very much for all of the incredible high-quality videos on a diversity of topics. Please enable variable viewing speed if at all possible.

Subscribed, this is a good revision video for young foundation docs as well as students. It's all there and it's all in order. Thank you.

You such a great teacher, your voice make learning enjoyable, so calm.

Dr. thank you so much. i have watched many of your videos. You really have an incredible talent in teaching. I have learned so much watching your videos, which really help me with clinical practice as Primary care provider. You make complicated medical subjects more easy to understand. thank you again

Thank you doctor, for your kindness explanation. It is pretty sure that I'll be always wait for your lessons. This video made my knowledge improve. Thank you again.

Wow what a soothing voice youve got. Dissipating all that exam stress, great work!

Very well explained, I was finally able to understand everything. Thank you so much. Keep up the good work!

I ❤️❤️❤️ your lectures. I’m a nurse and gleam so much information from your videos. I review them over and Over again. I’m a very visual learner and really appreciate your teaching style. Again, thank you so much for all the time you spend in preparation and teaching 😊

What a wonderful speaking voice and professional explanation! Thank you so much! This really helped matters.

Thank you soo much .Great Video.I recently had a blood test ,I wish I could get you to explain it to me .Beautiful voice.Keep up the Good work.

Thank you so much, I listen to your lecture videos and they are logical and easily understood. Thank you again...

Excellent! Would you consider uploading your voice so it can read me "Bed-Time Harrison's Principles of Internal Medicine Stories". Indeed, your teachings made me appreciate internal medicine again.

Thank you so much. Your video lectures are well organized and simple to understand. Please keep up the good work.

Your videos make me love medicine again. Thank you.

Love your videos! You are doing a great service to up and coming medical professionals!

I am in the nursing school. Bad professors that I am literally teaching myself using books. I was lucky to find your channel, I am surviving thanks to your videos. My best professor ever. I am recommending your channel to all my classmates and instructors as well at least they use them to learn how to explain the material lol...Thanks a million Dr

Thank you for the clear explanations. This is a great resource to help supplement my lectures!

I just started PATHO and I came across your teaching, you made it so easy to understand. Thank you so much !!

Wow ,no words just thank you and may God give you enough time to teach physcians around the 🌎

Soothing voice, informative, great drawings.

I am a junior doctor, thank you so much for these lectures. Please feature case studies like you did for the excellent acid-base lectures!!

Thank you for explaining it so easily, keep doing this type of helpful videos!

Thank you for your videos! Very helpful simplifying all the information we learn in school!

Step 1 in 2 weeks. Needed this! Thanks a bunch!!

I did my blood test yesterday after 5 weeks of 100% no carbohydrates no sugar no fruits no starch no red meat diet. My Liver panel test result shown AST , ALT , GGT level all perfect! Far from its top range. Just 5 weeks. My fatty liver is reversed to healthy normal. I lost 4-5kg just from dieting and stop eating after 7pm till next day lunch. 2 meals a day. Only boiled using water, steam Fish , tofu , cabbage broccoli veggies , chicken breast , black coffee no sugar for afternoon lunch and green tea no sugar during evening dinner not later than 7pm. After 7pm I fast till next day lunch 12pm. The fasting time is extremely important as this time allows digestion and some hunger which makes our body burn the fat within without exercising. Exercising barely able to reach the fat around our liver. So fasting is the effective way. I had No milk (contain high fat and high sugar) . No snacks. No all kind of bread which still are carbohydrates. No cake. No biscuits. No rice. No noodles. No fruits especially as it’s fructose are directly process only by our liver! Just 5 weeks and fatty liver is back to normal with proven liver function blood test compared to my previous test result 5 weeks ago. I feel very lively light and positive. I lost 5kg. Also My cholesterol and sugar level were also extremely good blood test result! I m looking way younger and my body is nicer too. I m 33 years old male. Non smoker non alcoholic. Didn’t work in a toxic environment. I didn’t exercise. But I ate much rice , fatty red meat, and milk and cookies and fruits. I slept late before. Now I kicked those bad habit n bad diet. After recovered from fatty liver, I continue my way of eating n fasting n sleeping time. I reintroduced some healthy carbohydrates back into my diet. Such as some corn carrot , some wheat bread, a little potatoes. Please make sure u do not overdo it. I really mean only some. Lack of discipline and taking it for granted will cause regrets. I’m sharing for mankind and for those who were helpless from useless doctors. And I’m sharing in memory of my late father who passed away due to end stage liver disease.

Your videos are great by the way! Really do appreciate your time and effort.

Thank you so much for this, reading chapters does not help me learn anything and I have a short attention span. This is perfect to help me study and retain information!!!

thank you! so well explained.

very clear and helpful! thank you!

These are AMAZING!!!

Brilliant, well explained.

I do really appreciate your way of explanation. Can you please do EKG start with basics ,tachy & bradyarrhythmia , ischemia .....etc ?

Highly appreciated, your explanation of the Liver Functions.

It was very helpful! Kindly name ur titles with serial numbers to help look for the consequent video in the sequence.

Excellent! You made it so simple to understand!

Great Video. Thanks for the help

thanks a lot. concepts r so well cleared.

Hi Medcam, What do you mean by ALT tells nothing about residual function. If you can please explain for me. Thanks

your videos make me complete as a medical practitioner

Really awesome explanation!

Understanding physiology is an Art ..

So so so incredibly helpful!

Thanks for this amazing knowledge

Thankyou doc! ❤

good one, thank you...

Thanks doctor..this big help me to me im a Physical Therapist...your very informative doctor...really appreciated.

Awesome Teacher! Thanks so much!

very good! Thanks

@Matt Mason, he was talking about fat digestion, i.e, what happens in the intestines. The lipid molecules are not coming into contact with the liver itself, but with the bile salts that are released into the duodenum. You're right in that when absorbed, the fats enter the lymphatics rather than the blood, so are not part of the first pass metabolism.

Thank you a million times 😃

Thank you. very easy to understand!!

Thank you. Very useful.

your videos make medical school the easiest place to be in

Could you please explain the role of liver in producing Insulin-like growth factor 1(somatomedin C) ??

This is great stuff. My GI doc is great, but he can't draw. Also it's a reminder of what he said. PS I waited over 2 years and just got my liver transplant 2 months ago. I feel great!

that is awesome thanks!

Any videos for interpreting abd ct would be great. Ty.

I like the smoke analogy. Thats a good one.

thank youuuu Sir 😀

Do you ever use albumin as a marker for protein-calorie malnutrition? I've read articles that indicate it's not a reliable tool to use for PCM? I still see hospitalists using it though. Thanks a lot for your excellent videos.

Any suggestions for controlling blood ammonia levels other than lactulose and rifaximin? I've read some studies on probiotics and zinc supplementation. Would glutamine supplementation be of value?

How recent is recent injury for the alt and ast to be elevated?

Very good lectures,Thanks

I'm a student in med school in Kenya and this video has the tests stuck more than what has been repeated in school since my first year!!Thankyou. please do pancreatic function and renal function test videos.

Hello Dr, Question: Can AST or ALT go up with recent heavy metal toxicity? Let's say someone mobilizes, via chelation, a large amount of mercury in the body and dumps it into the liver at all once. Would this show up as elevated ALT and AST enzymes?

thank you very very much

Nicely explained! Thanks

Interesting, how you left out what is common under the current Liver Function Test standard that includes the ALP and GGT now,

Can you show me a whole liver operation because I need one and I need to see what I got through

Thank you sir.

Excellent 👌

Can you do one on the heart ? Please :) This is an awesome video

What happens when you have higher level s of gamma gt please let me know as i have higher gamma gt in my bloods

Really nicely explained

thankyou great!!

THANK YOU

Congratularon Darren.

Thank you for the video! And I would like to correct something. Prothrombin time(PT) is not raised in Haemophilias. You told in the video that it is raised. PT is normal amd aPTT is raised in hemophilias! :)

great lecture

Albumin is low in chronic liver disease and Nephrotic syndrome?

Hi I'm presenting with high Alkaline Phosphatase and a few other symptoms of possible liver disease. I am having a GGT test done tomorrow and finding out what my ultrasound results are. I've had dark, not yellow, urine once. No appetite. Distention of upper GI and pain. Belches and flatulence as well and some nausea plus abnormal bowel movements. I'm hoping to get good news 🙏

You state that, "the PT is the most sensitive blood test for liver disease." I am curious why that is the only level of the four covered in this video that is not included in a CBC?

Sir, So high ALT is not so much problem,.how can I reduce it as I have low haemoglobin and high ferritin iron, please.

Hello sir, this was amazing... It really helped alot .. this can be transform into chronic condition if proper care is not taken ... So you can take liver detox tablets .... Liver care pack for better results. Take care...

Around 3:30, the Dr. Seheult says that all the fatty acids absorbed by the intestines pass through the liver. I thought that lipids and their components (fatty acids) bypass the liver and enter circulation via the thoracic duct ... anyone have insight on this?

At 3:22 you said "all of the fatty acids". I thought long chain fatty acids were packaged into chylomicrons by the small intestine and dumped into the lymph bypassing the liver in the first pass. Can you please clarify this?

Sir.. your lectures are osam

very good sir .easy to understand

Thank you very much! :-)

I just learned i have hep-c this helped me understand what the Dr. was talking about thank you, mike

Thank you you cncisr unforgettable presentation,you special sir

thank you

very nice

Could be more specific , it is the bilirubin in the bile that makes the "faeces" brown. Overall alright but being more accurate would help. Thanks !

Is factor 9 part of the intrinsic pathway of coagulation and if so then PT would not indicate a deficiency of factor 9. However a deficiency in factor 5 would impact the PT.

Good lecture

I never understood this clearly....Thank you so much