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Application of Luteal Phase stimulation
Luteal phase stimulation (LPS) has been successfully applied in the following:
1. Fertility preservation in patients with cancer.
2. IVF patients, normal population .
3. Egg donation programmes.
4. Patients with low response.
Principle behind this (LPS)
Generally it is observed every month that a dominant follicle is selected during the early-mid follicular phase of the menstrual cycle, However the presence of developing follicle has been observed on more than one occasion during the menstrual cycle in some women( waves). Most women develop a major follicular wave in the follicular phase in which a dominant follicle is selected and one or two minor waves, in which dominance is not manifest, in a single interovulatory period.
According to these studies, there would be constant availability of viable follicles, also during the luteal phase, susceptible to respond to gonadotropin stimulation.
( source: Luteal Phase Stimulation,F.Martinez et al, Frontiers in Gynecological Endocrinology,Volume 3
12 ноя 2018
