Seems to me having just built four custom doors for my new shop that a primary reason for building your own is to increase the thickness to allow for adequate insulation. Makes no sense on a wall system with eight inches of insulation to then install 1 1/2" doors. So here is the problem with seven inch thick doors: no one makes any kind of affordable lock system with knobs or latches. Hinges are no real problem to make for me but locking systems are not in my wheelhouse. I am in the process of modifying a German built lockset so we will see how that comes out. With a metal through frame I take it you are not concerned with heat loss?
Metal makes good frames because compared to wood it doesn't flex or contract as easily due to weather and better for wear and tear. You would be quicker just cutting the hinges if you wanted to get in.
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