MAPK/ERK Signaling Pathway 

I've watched a few of your videos now. They are so much better than our revision slides... Thank you! Keep up the good work

All your videos are phosphorylating my work!

Just what I needed. Concise, accurate, and clear. Thanks for the vid. :)

Damn🔥🔥there is so much information in just less than 7 mins ...amazing thankyou🙏

Thanks a lot, Sir. This couldn't be taught any easier!

Amazing explanation. Couldn’t thank you enough!

you're keeping me alive in medical school. Thank you so much ♥️

THANK YOU SO MUCH . THIS WAS EXPLAINED BETTER THAN IN MY LECTURE

Great video that puts everything into place! Thank you!

You are a true gem keep it up

i love this, i love you, thank you

Great video completely cleared my concept thank you 🙏

It's amazing how I was reading about Polycystic Kidney Disease, and how this pathway produced the entire physiopathology, or at least part of it. You save my life men, u are amazing.

I'm getting so much help by watching your video lectures for the preparation of my college studies. Thank you so much Sir for all these because it not only makes us feel interested towards the topic but also makes it way easier.

You are simply awesome..thank u

Now I don't have to read through a boring chapter. Thank you!!!

🔥Excellently expressed sir. Thank you so much.

Thank u soo much for all ur effort ... ❤

جزاك الله خيراً ❤

thank you so much, this helped me so much for my exam tomorrow! I would've failed without you

It's hard to find niche channels like this for medical sciences. You are filling the biochemical niche very well ❤️😁

thanks for the explanation. I've seen Neurofibromatosis disease mechanism today and learned about the neurofibromin protein (NF1 gene) but couldn't understand its function at first...now I see that neurofibromin is GAP that stops MAPK/ERK signaling pathway. thanks a lot

Thank you.

Every detail and interchangeable word used in publications that make them confusing to follow is excellently captured and explained in the video. This lecture is more than 5-⭐rating. Thank you so much!

I really liked it man.thanks

Thank you very much! helping me through my masters

Thank you soooo much !

Thank you so much 🥺

THANK YOU. only clear and detailed video out there on this process

Thanks alot..

God bless you!

Perfect man!!

شكرا على هذا الفيديو الجميل بارك بك الله

You make such pathways so easy. Thanks a lot hussain.

Ur smart and hard work make things easy for us .. thank u so much

Thank you sir, may almighty God add you more knowledge

Very good

Just by seeing ur video for few minutes one can understand whole concept easily... Thank u..🙂make more videos on csir ugc base hot topics

Perfect video 🌹🌹thank you

Thanksu so much sir to make video on this topic. I can readily understand this mapk pathway.

GReat ..its excellent video

Tnk u sir for such a perfect video lecture..

Nice analysis bhai

thank u sir....itz very helpful...keep making such awsome videos..

Very nyz class...👍 everything is clear,and easy to study.. Thank you

Thank you sir

hello, there is something I dind't understand... does this pathway, just like AKT pathway and STAT pathway, happen in all immune cells, such as tissue-resident cytotoxic T cells (IE-CTL)?

Very well explained 👍

Very good representation 👌👌

Hi, Sir! Its really very good video and clearly understandable. So thankyou very much... I have a suggestion that the subtitles should be error free.

I'd like to thank you for your excellent explanation! I've a question though, is this pathway similar to the RAS map kinase pathway? Or is it different? Thanks a bunch 😃

Just woww But I would like to give a note : The Ras is active only when it is attached to the membrane. When Ras is in a free formule in the cytosol, then it is inactive. It is just a remarque. Thanks for all from France 😁✌🏻

This pathway seemed dauntingly complicated until I watched this video... Great explanation, even comprehensible to a high schooler like me haha

Nice video sir it helped me a lot

cleared my concepts.. thank you

Thnkuuu sir ... beautifully explained...

After reading 4 tym. ...wz nt able to get it....Sir u made it 8 once....👌👌👌👌thnx a lot

Just wondering if the dimerisation of the receptor is due to cross-phosphorylation or auto-phosphorylation ?

thanku sir... nice video... great efforts.. sir have a confusion that raf is not phosphorylated... it is only kinase which is not phosphorylated, recruted by Ras..

Ras protein binds to GTP and ERK binds to ATP, what is reason for this difference?

u know , you r GOD. amazingly nice. u saved me .

No words hussain shab. Panun kashur boiy 😜

How to erk phosphorylat RTK

Who is STAT stimulate oct4

Wow amazing.. Just I wanted things.. Are you a medical student? Keep going man.. Iam a biotechnology students.. It's really helpful..New subscriber ❤️

ERK does not traslocates to the nucleus?

😊😊😊😊

hmm,,onk valo poriskar holo ebr byapar ta

Nice sir

I like this video, but Ras does not phosphorylate Raf. Instead, it binds it, and that is what activates it. Most cell biology textbooks like Molecular Biology of the Cell or Lodish Molecular Cell Biology explain it this way with cited experimental assays as evidence.

Muacks ty

Do you have a video (if not can you make one?) on tor signalling?

WOW

Need new vedio

Good explanation but please slow down

Excellent video Hussain. I think one only important thing missing from the picture @3:12 is what phosphorylates RAF. From another video (ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-ql62kMK3BrM.html) what I learnt is that a scaffolding protein binds RAF (which is bound to Ras) as well as Src kinase to form a complex. The scaffolding protein increases the local concentration of Src and RAF allowing them to interact. Src then phosphorylates RAF to fully activate it. I just subscribed your channel to learn more basic biology. Many thanks as you are doing a great job!

Are u a kashmiri by any chance

KInda of topic, but if you want to be precise with your drawings please draw the nuclear membrane with four layers of phospholipids, not like cell membrane that has only two layers.

Ras is not a kinase

wariyah asil