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Molecular docking using Discovery studio software 

Dr. RAVIKUMAR CHANDRASEKARAN
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#moleculardocking #discoverystudio #dockingtutorial #moleculardockingtutorial
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#ravikumarchandrasekaran #crkphy #amazingknowledge

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3 окт 2024

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Комментарии : 84   
@waqarnasir6916
@waqarnasir6916 2 года назад
Thank you for you video, but my question is about the Dock ligand options is not available in my discovery studio software. Kindly tell me about this.
@sailendramahanta2213
@sailendramahanta2213 4 года назад
Good explanations
@sunitaroy5310
@sunitaroy5310 Год назад
Sir, thanks for this valuable lecture. Kinly guide about, How to satisfy the valency in pdb ID chain ? Using discovery studio software.
@qfcristhianrodriguez
@qfcristhianrodriguez 4 года назад
Hello, I´m fron Perú, It´s awesome, i need to learning it.
@phdians7438
@phdians7438 4 года назад
Nice content buddy keep it up..waiting for more such videos.
@crkphy
@crkphy 4 года назад
Sure. Thanks for your valuable feedback and support.
@mugisasimon6459
@mugisasimon6459 Год назад
What CDOCKER score is suitable for pulication. And i request for your insight of how i can relate this to other docking softwares for the validation of my results coz,,,,CDOCKER scores usually be in -20's.....above...yet in other wares like autodock,,it will be in -6,,-7....
@mustafakadhim4845
@mustafakadhim4845 4 года назад
good explain sir can you show how do the organic metal. regards
@al-baghdadibaraaadilhadipm1222
@al-baghdadibaraaadilhadipm1222 3 года назад
Great video and simple explanation, my question is should I remove all ligands and add H atoms as a pre docking step? Secondly what does unfavorable bump interactions or unfavorable doner interactions mean? Lastly, I followed ur procedure and all I got is failed to generate a complex... Any suggestions? Thanks
@adedanova9247
@adedanova9247 4 года назад
Thank you for your video, this is very nice. actually, i am biginner in this area. i have some question about docking: 1) in my work, i use CDOCKER for docking, but you use libdock, so what is it different between this tools? 2) i am also curious about this content, may be you can explan about this program for biginner students in the next content.
@bhapree4407
@bhapree4407 3 года назад
If you use CDOCKER you must prepare the receptor protein and ligand before running the dock, in libdock you don't have to prepare and minimize the data prior to docking
@Winbugs1
@Winbugs1 Месяц назад
please give the link f previous video.
@郭娜-s3f
@郭娜-s3f 4 года назад
Thanks for all of your vedio. Could you please share some video about small and small molecule structure calumniating using Discovery Studio? Thank You!
@crkphy
@crkphy 4 года назад
Thanks for your support. Sure soon I will upload.
@دبسامالصافي
@دبسامالصافي 3 года назад
​@@crkphy dear i have not ligand docking option please tell me how i get it
@vikarahmed4469
@vikarahmed4469 4 года назад
Thankyousomuch sir !! The videos are really helpful. You're doing a great job ! :) Request : can you please make a video on active site prediction using online server and software like pymol etc, give bit details on result analysis. Thankyou again! :)
@crkphy
@crkphy 4 года назад
Thanks for your support. Sure.
@jyotisankarprusty1419
@jyotisankarprusty1419 4 года назад
After docking using ds visualizer, how to know about docking score of receptor-ligand complex?
@蒋超凡
@蒋超凡 2 года назад
Thank you for your video! I have a doublt: when I use cyp51 for docking with azoles, do I need to remove the heme like you did?
@prof.sanandachatterjee3232
@prof.sanandachatterjee3232 Год назад
Sir the molecular docking is successful
@royalslifezone2431
@royalslifezone2431 3 года назад
Put a video on the calculation of Binding Energies for the lig - receptor
@uddhavmukati3235
@uddhavmukati3235 Год назад
Sir i am not getting the dock ligand option, what should i do?
@balaji6491
@balaji6491 2 года назад
Sir. I downloaded and installed the biovia DS visualizer. But dock ligands options are not in that software. How to enable the dock ligand option. Is any cracked version available.
@chandramadhi4783
@chandramadhi4783 Год назад
Same doubt
@aqsasalamat135
@aqsasalamat135 Год назад
sir thank you for your video. Sir. I downloaded and installed the biovia DS visualizer. But dock ligands options are not in that software. How to enable the dock ligand option. Is any cracked version available?
@crazysatya1431
@crazysatya1431 2 года назад
can we predict docking score also!
@debayandas9373
@debayandas9373 3 года назад
can i use this software for protein protein docking . i want to check their interaction. plzz help
@nurlianafarhana7241
@nurlianafarhana7241 3 года назад
Hi sir is discovery studio client different with biovia discovery studio visualization
@pyush3
@pyush3 3 года назад
By which parameters we can sort out the best pose
@wajihaakmal1615
@wajihaakmal1615 Год назад
sir mera discovery studio pe dock ligand or is k nichy waley dono options nae aa rahy, kindly can you help me what's the fault present here?
@akinlamiloadeyemi2581
@akinlamiloadeyemi2581 Год назад
Pls can you send me the link to download the Discovery Studio Client?...
@irfanahmed6766
@irfanahmed6766 3 года назад
plz show binding energy ?
@sanchitadey8130
@sanchitadey8130 3 года назад
Sir, I'm not able to spin my molecule and protein, pls suggest some way out for this.
@khusboogupta5641
@khusboogupta5641 2 года назад
Sir, my Discovery studio is not showing lig dock block, it's shows only view interaction & define and edit binding site.??
@PARTHI360
@PARTHI360 4 года назад
Sir.. I have a doubt. How to convert my own organic compound (synthesized in lab) into ligand?
@sanjaynagar4098
@sanjaynagar4098 2 года назад
i am unable to find docking option in discovery studio. Please help
@yuvrajk.c.9665
@yuvrajk.c.9665 2 года назад
can you please make video on molecular dynamics simulations using discovery studio. I am stuck with simulation my rmsd value for receptor is around 5 A and for ligand is 17 A
@bejaouimarouene9113
@bejaouimarouene9113 4 года назад
Thanks you for this video,,but please if we have two drug molecules (like: flucanozole and Ibuprofen) , in this case can we dock these molecules (complex formation) and obtain interactions?
@crkphy
@crkphy 4 года назад
Thanks for your valuable feedback. In future videos I will demonstrate how to do.
@localsofindia1457
@localsofindia1457 2 года назад
how to find no of hydrogen bonds involved in the interaction
@ahmedreda2848
@ahmedreda2848 Год назад
how i can download the full version
@sanjaygopi6807
@sanjaygopi6807 4 года назад
Make video on docking with metallic ion containing protein like Zn and Cu
@norsyifaashafai7082
@norsyifaashafai7082 3 года назад
Hi there. Hope you can help. I actually accidentally right clicked thr view interaction and clicked the close button in the receptor - ligand interaction section . Now, I can't view any interaction and cannot choose 2D diagram. Hope you can help me, and make the view interaction button is visible again. Thank you so much
@malligasivan
@malligasivan 4 года назад
hello please explain about forcefeild tool and how to save file after force feild applied
@diptendusarkar1912
@diptendusarkar1912 3 года назад
how to analyze energy of each docking pose here?
@amitadash5961
@amitadash5961 4 года назад
I dont see the "Dock Ligands" option in my DS visualiser. Can u please help?
@دبسامالصافي
@دبسامالصافي 3 года назад
me to
@shobhaupreti6123
@shobhaupreti6123 3 года назад
Me too. Can anyone help with this?
@cesarioajpicondori6478
@cesarioajpicondori6478 4 года назад
Thank you very much for the tutorial. This DS 2016 Clien, do need to install Pipeline Pilot DS to work?
@crkphy
@crkphy 4 года назад
Thanks for your valuable feedback. Yes we have install pipeline pilot DS.
@cesarioajpicondori6478
@cesarioajpicondori6478 4 года назад
@@crkphy Thank you very much. Can make a tutorial how to install DS 2016 client+Pipeline pilot?. Thanks.
@KAYASeckin
@KAYASeckin 2 года назад
I am new to this application. Can someone explain to me? I am using the Discovery Studio Visualizer application. Some tabs are missing from the application in this video, how can I activate them? or how can I download this app?
@originalalive
@originalalive Год назад
How do you get low ping at localhost 9943 ?
@abdeentunde7040
@abdeentunde7040 3 года назад
Can you kindly drop the link for downloading 'discovery studio client' ?? NOT DS VISUALIZER
@shivarajag2293
@shivarajag2293 3 года назад
where I can get docking energy from this method?
@nivethan7313
@nivethan7313 3 года назад
How to calculate RMSD value sir?
@ishfaqnazir8796
@ishfaqnazir8796 4 года назад
Hi, can you provide the link to download this software
@sonam1623
@sonam1623 2 года назад
sir can you please share the link of discovery studio client for download
@dr.khalifa1595
@dr.khalifa1595 3 года назад
Is it free? Or do you have a cracked license, plz?
@دبسامالصافي
@دبسامالصافي 3 года назад
may ne
@ayumuyuukina2030
@ayumuyuukina2030 2 года назад
tried this tutorial but i dont have the "dock ligand" option. all i have are just "view interaction" and "define and edit binding site". what should i do?
@meenakshisingh4712
@meenakshisingh4712 2 года назад
Same here. 😕
@AmirulIslam-lg6tk
@AmirulIslam-lg6tk 3 года назад
Please help me. I don't find "Dock ligand" option in "Receptor-Ligand Interaction" tools on my Discovery studio. What should I do?
@دبسامالصافي
@دبسامالصافي 3 года назад
dear i have same problem , if u solved it please tell me
@sovendhawa9538
@sovendhawa9538 4 года назад
The version that you are using is a paid one??
@crkphy
@crkphy 4 года назад
S
@sovendhawa9538
@sovendhawa9538 4 года назад
@@crkphy can you please inform me how much does it cost?
@muqeetsoomro
@muqeetsoomro 4 года назад
@@crkphy thanks for tutorial, what is the cost of software
@mujeebmushtaq1583
@mujeebmushtaq1583 2 года назад
Its very helpful. Guide me to get the crack of latest discovery studio or how to enable its additional features. if you have crack let me know i am interested. look forward for your response
@zoilagandara5726
@zoilagandara5726 4 года назад
I have Discovery Studio Visualizer and the option Docking Optimization I could´nt found, how can I get it?
@دبسامالصافي
@دبسامالصافي 3 года назад
if you solved may you tell me
@diptendusarkar1912
@diptendusarkar1912 4 года назад
Dear Sir, when I am opening by following your method, in my down loaded software I am not able to see following icons ..dock ligands, highg throughput screening, docking optimization, scoring etc..kindly help me to find all those in my software.
@alifarak347
@alifarak347 4 года назад
Same problem with mine also!
@mounirraji3880
@mounirraji3880 3 года назад
Same for me if you found a solution help me please
@localsofindia1457
@localsofindia1457 2 года назад
Discovery studio is not free sofrwore. So options will not show
@mechancial
@mechancial 4 года назад
Is this software available free ?
@papiachowdhury839
@papiachowdhury839 4 года назад
I have discovery studio visualizer, how to get discovery studio client?
@crkphy
@crkphy 4 года назад
By purchasing license u can get it.
@papiachowdhury839
@papiachowdhury839 4 года назад
@@crkphy Do you have any tutorial on viewing docking results through pymol?
@jyotisankarprusty1419
@jyotisankarprusty1419 4 года назад
@@crkphy Could you suggest me the procedure for purchasing license file of ds client?
@sinhasuman1944
@sinhasuman1944 4 года назад
It's a paid software, right
@crkphy
@crkphy 4 года назад
S
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