0:00 to 6:50 is Anatomy and Function of GFR 6:50 is complications of nephrotic syndrome 21:42 Pathophysiolgy of different causes 40:23 Diagnostic Approach 1:01:28 Treatment 💉
Sir, in treatment section you said management of proteinuria by reducing the protein uptake. but NS patients have already loss of protein and ongoing losses, so if they use to take low protein diet. they may future absence of protein in serum, that will worson symptoms. thank you for your valuable video!
How is this guy just a PA? Unless I missed a degree. He has a mastery of all his subject matters and this guy hits everything. In great detail - 90% of office docs have now idea what he’s talking about 95% of the time. Just wow. Wicked smart and knows how to present. I’ve watched too many hours now. Lol If you live near him - that’s your doctor. Amazing job on these videos. Truly impressive. Keep it up Zack.
I think you're right that he is a PA. He's got a team helping him out, and this is his full-time job as far as I can tell. No idea why he didn't just go to medical school if he was going to study in this much depth anyway. But there is nothing about being a PA that means you can't learn at this level. It just means you are usually not required to learn it in this much depth the way an MD is. For the record all of this material is fair game on USMLE Step 1 and 2. I can't speak for doctors who are years out of practice, but as a med student, this is definitely expected knowledge.
@@bryan5065 I guess he'd lack clinical knowledge. It's fine and dandy to know this stuff very well, but in reality when there's a patient you have to talk to, attend to, listen to. It's a different situation. I'm 5th year and I've learned this the hard way. Patients aren't books you can just read. I feel like an idiot walking into these situations and there's nurses who have years of experience who could do my job better. But I have years left to learn in a clinical setting, which unfortunately isn't something we can give to everyone. After all, our work is practical, and you can't just learn that from a book.
I struggled with this topic at our physiology lectures we literally lost because our prof made it shch a complex subject , but you are simplified it a lot due to your ability of delivery info in smooth way now we know from where we enter and at which point we leave and wrap up . Thanks
Hello zach thank you very much for helping me through my medical school i started watching you since I was a 1st year student now I'm a Gp for 2 years even as a doctor I'm still watching every new video you make. You're my online doctor who keeps teaching me so thank you very much for your hard work.
This was an amazing educational review. Thank you. As a genetic counselor, I appreciate that you mentioned genetic causes for more rare kidney disease. In mentioning African American and Hispanic individuals in association with FSGS, I think it would be valuable to mention APOL1 mediated kidney disease as in primary cases with unknown cause, APOL1 may well be a driver. As such, genetic testing would be a reasonable consideration in such scenarios and there are ongoing clinical trials that are likely to lead to valuable therapies in the near future, which will help preserve the function of native kidneys in these individuals.
GBM pore is bigger than diaphragm of podocytes , which means that Red blood cell can’t go through podocytes because they can’t even penetrate even bigger pore like GBM. But why in nephritic syndrome, where podocytes are ok even thought GMB is damaged, red blood cells can penetrate podocytes?
You are such a good teacher! I can smile, laugh and enjoy while I learn all these hard topics. You give all the information that I seek, I want to understand it ALL, not just peaces and you give me everything! Most of the time I only get peaces of udnerstanding from school, that makes med uncapable of understanding symtoms fully. Im so grateful for your work! Im also a subsvriber to your website. You rock!
Can someone answer me please, the protein is negatively charge, and the one who damaged at nephrotic syndrome is podocytes, we still have the glomerular basement membrane that ngeatively charged too, and will prevent the protein to go urine, so how it can be?
Growing up I had this. I have been in remission for I think 7 years. I was so little when I had it I really don't remember a lot about the chemo and all that. I wish I remembered more, but at the same time im happy I don't remember all the appointments and the kidney biopsy's and the chemo that made feel awful. At the time I did not understand why my church sent my mom voice messages praying over me. I don't really know how it worked so I found this video. I am clueless about the dormant kidney disorder I have and it kills me that I don't remember the faces of the other kids in the chemo room with me getting treated with what they had. I wonder how they are doing.
Same. Helped explain a very complex topic. I just completed my 1st rituximab infusion. I have primary menopause nephrology. Thank you so much sir for your explanation.
@@robertjohnson2879 My girlfriend (119lbs) will be doing her first infusion treatment next Friday. How did you feel while being treated and afterwards throughout the rest of the day? Best of luck to you Robert. I’ll keep you in my prayers and sending good vibes your way.
