What do you think about the conclusion at the end? 💊 MicroVitamin (multivitamin & mineral that I take): drstanfield.com/products/microvitamin 💪 Join Patreon for early access to my videos & Discord chat: www.patreon.com/bradstanfieldmd 💊 My full supplement stack: drstanfield.com/my-supplements
I think that like a lot of these trends like a caveman seeing an automobile. Cave man is smart enough to see it runs on petrol so thinks washing the car in petrol and putting petrol in every portal into the car will make it run faster.
I agree with your conclusion, that one study only talks about collagen protein, not peptides. And there’s a lot of good evidence like the one you’ve shown on this video collagen peptides are indeed beneficial.
I'll continue with my daily shake at lunch, 20grams of peptides, cacao with phenols, 5g maca root with 5g of pea protein included and green coffee bean, and 3 teaspoons of triple fiber (acacia, psyllium, and inulin). I mix this with banana milk.
Started collagen over 2 years ago because of pain in my hips which is hell when you’re a side sleeper. Six weeks on the pain had completely disappeared! Call it whatever you want but that is just enough for me, a sixty year old, to keep investing in collagen peptides for the rest of my life.
Collagen from bone broth has kept what was increasingly disabling arthritis in remission for me for years now, & repaired hair & nail problems caused by a previously so-called 'healthy' excessively plant based diet.
@@jorgelizaso978this one they showed in the video with the 🐮 baby blue on the container . Is a good one!! It does help.✨there’s another one you can trust also from “ ANA MARIA LA JUSTICIA “.. Ashe has her own brand. She is from Spain, and has many years giving conferences talking about this collagen supplement as well as other supplements,for example “ magnesium “ deficiency… e. t.c. A trusting brand.✨
Taking Collagen has had a clear and obvious effect on my skin. For me, it absolutely improved my skin. I just add a couple scoops in my coffee every day and my skin is very smooth and young looking. I'm 57 and so the "before and after" is not subtle at all. I can recommend to anyone and everyone.
I had knee pain that came on and off for decades. Brought it to different doctors and specialists and none of them were able to figure it out or solve it. The only thing that gave me relief was regular collagen supplementation. In just under a year my knee pain gradually disappeared. Now I’m pain free.
Similar experience here... I started having knee pain in my right knee two years ago from doing so many hours of driving during the summer making Uber eats delivieries for extra cash. I stopped driving long hours, and my knee felt better, but it would still agrivate me enough that I'd just been taking ibuprofen every morning since then. Back in June, I started taking a Collagen Powder in my morning ice coffee (it has verisol, fortigel, and fortibone in it) for vanity reasons, I wanted nicer skin... I never thought about it helping my knee, but by the end of July, i realized that my knee wasn't hurting me anymore, and i finally stopped taking ibuprofen after a year. Did my knee just need two years of healing and taking ibuprofen, or did the collagen powder finally help it heal all the way? I believe in the collagen powder.
@@Nobody-Nowhereok controversial but if it worked for them let them (even if it was just the placebo), if they stop taking it the effect will go away
Dr. Stanfield, Thank you so very much for your diligence in researching and comparing so many different studies that, for the layman, can be very confusing and/or misleading. I am a healthy, active 79 year old woman who believes in holistic health and in taking supplements. Being on a fixed income I must pick and choose wisely which of the reverse aging supplements I can afford. I trust your expertise and your judgment and truly appreciate you sharing your own regimen with your followers❣️🐅
Just started collagen not too long ago. Was never a believer in collagen. I can already see a difference in my face complexion looking better, and my nails growing faster. I’m definitely not protein deficient either. The reason I did not use collagen in the past was because I consumed well enough protein. But after listening to so many anecdotes about collagen use, decided to give collagen a try, and I’m not going back.
This latest study reminds me of the fitness industry, specifically single studies on muscle hypertrophy that start with the wrong question or faulty assumptions and then produce results that are generalized. For example, such and such exercise doesn't protect you from injury, says this new study. Only, nobody used this exercise because they think it protects them from injury. Yet, fitness influencers are quick to say, don't do this exercise, according to the new study. Your results are only as useful as the questions you ask.
Isn't this with about 90% of the studies you hear about? Once you've looked deep into a topic, most questions asked by studies make no sense (to you). They may make sense to somebody, though, from a different perspective. Like Vitamin D supplementation studies where the Vit D serum level is never measured (yes, these studies exist).
Your thought on 'starting with the wrong question' is pervasive in so many scientific studies. I will also add the fault of not addressing confounding factors is also a massive issue.
That would be injury from exercise, so the question was does the supplement help you heal better and not get injured as much working out, which are hypertrophy questions.
@@TwdlD there are no wrong questions, only questions that are relevant or irrelevant to you. It's up to the person reading the study to decide whether it applies to them.
Back in 2020, I started a job that required a lot of walking (at least 20 kilometres, 5 days a week) and it wasn't long before I started feeling a tingling pain in my knees and my ankles. Back then, I had no clue about collagen. All I knew was any issues in or around bones means taking calcium, D3, and K2. I found out about collagen through online forums and decided to give it a shot. What it did for my knees and my ankles was no short of astonishing. It started to reduce the pain and eventually made it vanish altogether while I continued to do the same job with the same frequency AND continued by intense cardio routine at least 6 days a week. This is not an isolated case as even my colleagues in that job had the same experience when they started supplementing with collagen peptides. I personally used a blend of collagen peptides and turmeric in the beginning. To this day, I take bovine collagen peptides so much religiously that my protein shake isn't complete if it doesn't have 10 grams of collagen peptides in it. (For anyone concerned about the 6 days a week cardio bit, it has been replaced with resistance training now 😉)
Im also adding 10g Collagen peptides into my smoothies but also taking Tumeric and 1000mg DHA fishoil daily, so im not sure what exactly is keeping my bones and joints pain free but it works. Also taking lots of other supplements but im pretty confident it's either one or combination of above 🌴
@@indiankid8601 i doubt 3 grams will do anything, you need between 10g and 30g per day. I only take 10g but I also take 30g whey protein amino acids, big dose fishoil and eat animal fats and skin, every day.
As someone who struggles with very dry skin and psoriasis patches, I definitely take collagen peptides to help with my skin specifically and I'm satisfied enough with the results that I've been taking it consistently for 3 years now. Living with dry, cracked skin is torture, so even 10-15% improvement in skin hydration is enough for me 😂
@@Lolipop59I'm taking FINE Japan Collagen, but I switch it up depending on what I can get my hands on because I just follow the criteria of 1) at least 5000mg collagen peptides per serving and 2) Marine collagen with no porcine elements (because of religious reasons).
@mirasingh7428 not sure about skin quality in general, but if you're like me and have extremely dry skin to the point where there is tightness and cracking, you will feel a difference.
I personally have been taking collagen daily from a brand called Renewed Health. Their collagen also contains vitamin C, zinc, silica, and biotin for the collagen boosting properties. For me, I really noticed an improvement in gut health and skin health almost immediately. Again probably due to the combo of collagen with vitamin C, zinc, and silica. Really incredible stuff!
@@Nobody-Nowhere Collagen is well known for improving gut health, so it might not be placebo. I do actually consider collagen to be a relatively 'poor' quality protein, but it certainly works for some people. I've never used a collagen supplement myself. Personally, I eat a mostly meat and eggs (hyper-carnivore) and that includes gristle, sinew, tendons, skin, anything that is reasonably edible, which is normally everything.
I think collagen peptides have made greater improvements on my skin more than any creams or lotions I have used on my face. Within 2 wks I already started to see the difference.
I’m in my 70s, a classical guitarist who suffered with extremely thin, peeling nails and tried everything for years; finally started adding 2-4 tablespoons of collagen in a daily protein shake; now have strong nails, better skin and hair, too. Also noticed joint pain disappeared. Collagen works if taken regularly.
Thank you for your input, I found his comment that most people take collagen peptides for their skin so therefore no discussion of joints to be rather dismissive even if that can be proved because many people are interested in the potential benefits for joints. I hope it will be addressed in future discussion as a lack of joint health as one ages is far more critical to a healthy active life than an 8% improvement in skin moisture or elasticity which may be addressed through other means.
I'm also a guitarist that suffers from dupytrens contracture, which is when collagen attacks your fingers. I'm wondering if taking collagen supplements will worsen my condition
@@paulfreedman8121 Interesting question. In theory, it might. dupytrens contracture appears to have a genetic component. So you'd want to find a top notch ND or functional/regenerative MD who can recommend epigenetic treatments. Self Decode may give you some clues.
Adding to the chorus of anecdotal evidence, collagen has eliminated both my shoulder and knee pain from injuries that left lingering pain for years. Now that I think about it, my skin is better too. I don’t believe it’s a placebo effect, given the severity of my past pain, so I’ll be taking it for life.
I see & feel 2 things *only* when I take protein powder (with all of the collagen types) 1. Removes joint pain in my knees 2. My skin gets very soft and bumps on the back of my arms disappears - I think it does help some with anti aging
@@flashgordon6510 Excellent! It definitely does something. I wonder if maybe it was the brand of Collagen they used ? I noticed the most difference when I switched from just a Type 1 to all types of collagen. I just know what I experienced and still do. =)-
I started to double my collagen from 1000 to 2000 mg about 3 months ago after I viewed your video on supplements (also doubled omega 3) Have not really noticed anything re skill but my knees have been brought back to functional👍(had 4 op on meniscus over the years two on each knee🙁) I now can play pickleball for over 2hrs without out pain😊 (Usually play 2x a week ) Not sure why but I’m gonna continue with the collagen and omega😊
That study was bad science! They replaced a reasonable dose of a good protein for protein synthesis with an equal dose of collagen, which is not a complete protein, and not very bioavailable. My guess is those given the collagen supplement were protein starved! Did they even used hydrolyzed collagen, which is much better bioavailable? The correct way to uses collagen is to add it to your ordinary protein, and not as a replacement. And utilize a hydrolized form. Just add about 10% of your proten as hydrolized collagen, or about 12 g. If the researcher had done that, they would have gotten results. Just like you do if you do it like that!
Fantastic video, thank you! I’ve seen other doctors on RU-vid jump on the collagen supplements don’t work because of that one study, when that study only talks about collagen “protein”, not peptides.
I am into Immunology and immunotherapy research work in Asia. There are many collagen supplements in the market and some may be marketing products of low quality and also having false claims. Its not easy to believe what these companies and manufacturers (big pharma) use in their supplements, not to mention the huge profit margins on these supplements making them extremely costly. I strongly believe in the consumption of fresh whole foods rather than go for processed supplements.
All I can say I definitely see a big difference since I’ve been taking collagen every morning in my tea. My skin elasticity is great and improved I stopped itching on my forearms neck and face. I no longer get heartburn after anything I eat versus any and everything I ate felt like it would come back up (and many times it did come back up) those days are gone.
My 80 year old parents started taking 1 scoop of vital proteins unflavored in their morning tea and said their joint pain and stiffness is gone, the only study I need.
Hmmm…interesting. I have been taking Ancient Nutrition collagen peptides and my nails were/are growing like crazy. I don’t really have any joint pain or skin issues. Anyway, I once tried the Vital Proteins brand and my accelerated nail growth stopped. Your parents may want to consider Ancient Nutrition brand…
Collagen is proline + glycine, both of which are easily absorbed. And the collagen "peptides" are broken apart by protease and stomach acid into those two individual amino acids anyway. idk why people keep buying expensive collagen when they can just buy those two aminos for much much cheaper (and increase the dose) Glycine tastes like sugar, and proline is kind of sweet too. I use them to sweeten my tea. To rejuvenate skin and joints, add hyaluronic acid to the regimen with the money you save.
@@larryc1616 however bone broth is very high in histamine, so it can severely disagree with people with histamine sensitivity and mast cell disorders. Since histamine and mast cell disorders are relatively recent discoveries, many who have them are undiagnosed. Those of us with these issues do better with supplements - but not all collagen supplements have the same benefits, particularly skin vs. joint health. I take proline, glycine and hyaluronic acid, but that can be fairly costly too and it is less convenient than a single supplement. Haven’t yet cone across a supplement with proline, glycine and HA - does anyone know of one?
I do believe there are specific peptides that give benefits for the skin. I've tried many brands, both marine and bovine, everytime I go back to one specific brand of marine collagen peptides due to how good my skin looks.
@@kathleen9456 It's a no-name cheap brand in Norway. I get that since I live here. Right now I'm looking into other well known brands with marine collagen to see if I get the same effects. I can report back.
male 47, I use collagen in an effort to preserve muscle and connective tissue and articulation health. My current course is 100mg vitamin C, 12g glycin, 20g collagen hydrolysate powder from beef. I do not count collagen in the protein consumed. From january to July I lost 14kg and the withings says I lost only one kg of muscle (so I lost mostly fat in the abdomen, the belt shrunk). The main strategy is low sugar flour ethanol, and more protein and fats, and do zone 2 walking fasted. Feeling is amazing, mood is stable happy, cognition and productivity at work are much improved. As a side effect I can see in the mirror face is also improving. The collagen powder taste great in salads, eggs, mixed in minced meat, or in sauces. I don't care if it works or not, I feel so great that I don't want to change anything!
Good video, topic was covered honestly and clearly... Personally I take both whey and collegen peptides.. not for muscle repair, but because these represent some of the best sources of cysteine and glycine respectively... And if taken at the right ratios, they cover most ( but not all) of your essential and conditionally essential amino acids...
@@freshstrt3140 absolutely... As a general rule, when considering the 9 essential amino acids, it's best to keep intakes to multiples of the adequate intakes for each one. As in if you take twice the AI for histidine, you should also take twice the AI for the other essential amino acids as well. When it comes to the conditionally essential amino acids, that's a bit more of an open question as this is an area of ongoing research. However when it comes to the amino acids cysteine and glycine, there is sufficient evidence to suggest that glycine should be taken in excess of cysteine. A 3:1 glycine to cysteine ratio seems to be likely to be close to optimal. There are multiple reasons for this, partly due to how the body uses more glycine than cysteine in a number of processes, and partly because when glycine availability is too low to sustain normal rates of glutathione synthesis, the consequent rise in tissue levels of gamma-glutamylcysteine results in increased conversion of this compound to 5-L-oxoproline that is then excreted in the urine, making glycine the the limiting factor in the synthesis of glutathione, even in the presence of excess cysteine.... As for how to achieve the correct ratios.. luckily, this is thankfully quite easy to achieve due to the unique properties of whey and collagen peptides... Although there is some variation between vendors, as a general rule, 30gr of whey protein concentrate and 5grams of collagen peptides will provide a 3:1 ratio of glycine to cysteine, and the correct ratios of all 9 essential amino acids... Hope that helps.
I do have a question to anyone who is taking collagen and saw improvements in their skin - what source of collagen do you use? Marine / bovine? What brand do you recommend? And if you were taking collagen from different sources and brands was there any noticeable difference? Thank you.
I started collagen several years ago. Didn't really think anything much about it - just started taking it and forgot about it. Well, after about 6 months (with no other change in my diet) - I was shocked at the following results. 1) my skin inflammation on back of elbows disappeared after 40 years; my skin elasticity returned like a 20 yr old (I'm now 70) - nothing short of miraculous; and my damaged left knee of 20 years seemed to heal itself - so much so that i could run high speed again on treadmill. None of those issues have returned, and it's been over five years since i first started taking it.
listen, I would pull my skin up on back of my hand and it wouldn't even drop back!! ! - that is how scary my skin was. After the collagen and for last 5 years, it literally bounces back like a 20 year old. I wish I could enclose a video to show you! LOL @@MarsX69
We have them. Lots. They just conveniently ignore them because they don't fit the plant based agenda since many amino acids are found only in animal products and the false consensus is that animal protein is bad.
The key ingredient are the 2 amino acids Hydroxyproline and Hydroxylysine, which our body needs to make using Proline and Lysine. Collagen is by fare the most abundant protein in our body. So eating small peptides with these amino acids from collagen, makes it for the ageing cells much much easier to absorb as compared to making themselves, and make new collagen. So most of these studies are difficult to compare as the body needs also good quantities of Vitamine C and Zinc to make these unusual amino acids for new collagen....in short, collagen works fantastic for my knees and skin!
The molecular weight, type (1,2,3), formulation (e.g. UC-ii), dosage etc have a huge effect. But perhaps also, what other ingredients were in the supplements? Sugar could reduce the effect. I also wonder if timing in the day makes a difference too. So many clinical studies show benefits on skin, joints and even gut lining.
Dr Stanfield, so many channel owners could take lessons from you. Your videos are always well organized, well presented, and easy to follow. You always manage to provide a significant amount of detail in a surprisingly short amount of time. Keep up the great work!
Dr. Brad, great as always. In the late 70’s and early 80’s I was in contact with Dr. Alibi at the Pittsburg burn center. He had worked with a number of peptides to accelerate wound healing. He indicated to me that certain dipeptides were much more effective than others at accelerating healing. I believe his pick at the time was leu-ala or gly-leu. So I think your hunch was correct about specificity. About that time, George Blackburn (who came under fire later for some of his publications) published a book called, “Amino Acids”, wherein he surveyed many of the studies to date that elucidated the mechanisms of peptide absorption, metabolic fate and effects. For example, Tyrosine might be conditionally limiting in athletes under certain athletic and dietary stresses. The information at the time supported the statement that, as a free amino acid, tyrosine is so slowly absorbed from the gut that it can still be identified in mucosa 4 hours later! But as a dipeptide with glycine it is absorbed in minutes. I think there is still a great deal of work to be done here, because good science is so hard. Our early conclusions may be invalid or, at least, insufficiently understood. But I think information has been available for more than 40 years that supports the conclusion that peptides can make a difference over intact proteins and that the composition of the peptides matters. Best to you!
The day after taking the supplement in your thumbnail shot, my hangnails clear up. Every time. I don't need more evidence than my self-experiments at this point.
I have been taking the same brand for years, and feel that it helps manage my Bone on Bone Knees. There have been times that Amazon was out and I had tried a different brand. I can tell a big difference if I use a different brand. My nails are not happy, but worse yet - I feel it in my Knees. The Brand is: Wellpath Renew and is about $24 when not on sale.
When you look at the biochemical structure (i.e. a tight helix) and composition of collagen (i.e. mostly glycine, proline, or hydroxyproline) it is clear why some peptides or peptide combinations are more important than others. From Wikipedia: the most common motifs (i.e. repeated structures) in the amino acid sequence of collagen are glycine-proline-X and glycine-X-hydroxyproline, where X is any amino acid other than glycine, proline or hydroxyproline. These simple amino acids are necessary to support collagen's tight helical structure and other larger or more complicated amino acids are only incorporated occasionally.
Unlikely, there are too many people including myself seeing an improvement. That said, I'm really more interested in the hope that it also does help with internal organs, since I'm rather into longevity, not just looking young. Great Work!
@@EkilRevolution Sure, taking it yourself is not a study with a control group. But if something isn't harmful and it's cheap, then I certainly won't stop taking it, just because the science about it's usefulness is undecided. That said, I wrote this before watching the video, and the study claiming that it isn't useful has it's own flaws.
@@NoidoDev studies very often return incorrect results, my only point was that your experience wasnt placebo controlled. i take collagen as well because it is high in glycine and low in essential amino acids and methionine. i have no idea from my own experience the effects of collagen, speculating on stuff like this leads to delusion and living outside of reality.
I mean just taking it to make sure your body gets the amino acids it needs for the day is good enough. The amino acid profile in collagen is amazing with all that glycine and it's very easily absorbed and utilized. It's also easy to take, virtually no taste easily dissolves and doesn't have hormone issues or lots of calcium like the problem with whey. It's all around just good for basic health and I've noticed that effect especially when sick. So that alone has been reason enough for me.
As usual, I’m pleased to see your in depth reviews of the studies to clarify the knee jerk reactions triggered by this release of a particular study. I will continue my collagen too! ..my nails, hair ..knee pain almost gone. I recently had a MOHS surgery on my nose… 2 days later I went to the plastic surgeon to fix the big hole left and he was amazed at the tissue strength and ease of doing the reconstruction. I’m 75 and he says usually skin is paper thin.. which mine used to be 2 years ago before taking collagen. Now it is no longer dry and itchy. My legs actually glow. I started lifting weights last year and feel much stronger with no pain. The MOHS surgeon said I had beautiful skin! So… I can see no downside of continuing the collagen. Now if they would invent a Time Machine to undo the sun exposure I did in my 20’s and 30’s! Paying the prince now! Use LOTS of sunscreen after you take your collagen. Now THAT will be a miracle combo!😍🥰❤️🩹
There was a mri study years ago which showed the improvement in cartiledge in bones, the skin has been well shown and it has been found in the tendons a long time ago when labelled compounds were used. There seems to be an inherent flaw in the methodology.
Ummmm, my elbow pain all but disappears when I use collagen. Not to mention the wonders it does for my skin. I don’t care how many studies say it doesn’t work, I’ll be using it. Seeing is believing.
I have heard about this study just recently from another RU-vid channel that I watch sometimes by Lane Norton, and even if it's true and that it doesn't help to grow tendons I am taking for the skin health mainly based on the information from this channel. However we have to admit that the mechanism of action is not clear .. so it makes sense to be skeptical. If everything turns into bunch of amino-acids in the stomach how it suppose to work differently? That's still unclear to me, or how the mentioned transporter suppose to work in that case.
Thanks for your comment. I agree that there are significant unknowns, as explained in the video. It's possible that there are specific peptides which offer the benefits from collagen peptide supplements
@@bonanzatimeOMG, same here. After one week, my hair and nails grew faster with Vital Protein but I'm too lazy to take it because of the clump and hate using it in hot beverages because it changes the taste and smell of it. I bought the tasteless one but I need motivation to use it. I wish Vital Protein could offer liquid collagen.
It doesn't matter if we do or don't know how it works, if it still works. It would be great if we knew how it works, but if the evidence shows that it works, then we follow the evidence.
@@SkepticalCavemanScience doesn't know everything and the fact that some studies show promising results doesn't really mean that it works. Maybe it works, maybe it doesn't work. Most of the studies on the matter seems to have a conflict of interest, so there isn't enough research to be sure. The fact that we don't even have a good idea why it would work doesn't make it better. So I would say that it does matter. I can give you a little analogy here. Maybe you have heard about the EM-Drive. There were multiple labs measuring thrust, but the described mechanism of action broke some basic laws of physics. After further research they found out that the force is generated by the earths magnetic field. So it wasn't actually scalable or usable in any way. So that's what can happen if the mechanism of action doesn't make sense and there is some evidence that "it works" until it doesn't work.
@DrBradStanfield from what age would you recommend one start supplementing with NAC / Glycine? What are your thoughts on the findings that it may impair muscle synthesis?
@marcocee197 There are no such findings! What GlyNAC does is restoring the youthful level of glutathion. Idiots can get the idea that it blunts the effect of exercise, because glutathion is an antioxidant. Do they also think that younger people has diminished response to exercise? NAC is also an antioxidant, with some health effects. But most of it is intended to be consumed building glutathion, isn't it?
biolayne, menno henselmans and other fitness influencers were quick to condemn collagen as soon as they learned of this latest study, but I can't find anywhere in the paper whether any mention of collagen peptides. That's confirmation bias for ya.
N group of one, anecdotal evidence here! Did this ( supplementing glycine, proline, lysine, zinc couldn't find hydroxyproline as a stand alone supp) while following a strict whole food, plant based diet. Saw nothing positive. Until I jumped on the marine collagen peptide bus. As an older female, my body needs all the help it can get. I'm rather annoyed with myself for sacrificing my skin and joint health on the altar of vegan dogma. But glad I woke up in time.
@@laurieparis2203 Thanks for the input! That’s interesting! I was thinking about trying the same as I am also vegan. I have been curious about vegan alternatives that might also have benefit versus eating collagen. I was going to start with just the 3 amino acids and maybe try Vecollal. If those 2 approaches do not provide benefit I, like you, will try and see if I get benefit from the marine collagen. In the end, we have to put our health first and just do the best we can 😊
@@anthonymccollim3769 Hi Anthony. Yes. I want to do the best for myself, the planet and animals. But there comes a point whereby I have to put my health first. Being unable to function due to hip pain, allowing my skin to wrinkle bc I won't take a collagen supplement that mitigates those problems, is madness. But within the vegan community one such "transgression", and you're a pariah. Or you're told it's all in your head, it's placebo effect. Mostly by young vegans who have no injury or arthritis. So beware!☺️ And best to you with those supps you mentioned! I hope your body will like them. There's so much individual variation in body chemistry, what works beautifully for one can do nothing for another. 🌱
@@laurieparis2203 I agree with you. If it helps you, and there are no other vegan alternatives that work the same, then absolutely take it. Yes, there are definitely some Vegans that can be judgmental and only accept perfection. It’s not about being perfect, it’s about doing the least harm possible. Sounds like you are very aware of doing the best you can for the planet and that’s great. I don’t think you should feel bad about taking something that helps you when you have tried other options first 😊 I am also considering this myself
If it is for wrinkles alone, then take a look at micro needling, the premises are that the body rushes collagen to repair the needle punchers and, in the process, rebuilds your sub layer, and also stimulates hair growth.
This channel is about general health optimization, especially during aging. I found it while being interested in longevity optimization. The hope is that collagen helps with some tissues and organs inside the body as well. Like you can tell people with a bad skin are likely to be sick, not only related to their skin. Then the other way around, good skin might indicate more benefits.
May I ask which type and brand you take? I have a long list of back problems that contribute to pain, so I’m hoping that at least some could benefit from collagen supplementation. I’m now considering surgery, but the doctor says that usually doesn’t relieve all the pain. 😥
I don’t know if you see or reply to these comments, but I did a deep dive on Collagen a while back. It showed that supplemental collagen does, for a time, increase collagen in the skin but after while it stops having any benefit. Simultaneously, natural production of collagen is downregulated significantly so that if people quit, they had a significant loss of collagen compared to baseline. This tells me that collagen supplements are only useful in temporary spurts and must be given long breaks in between. But better yet, why use them at all if all they do is turn off natural production? What are your thoughts on this Doctor?
Statistical significance shows the odds of a result having occurred by chance versus as a result of what is modelled, it does not show strength of effect. IE "significant improvement" and "statistical significance" are not synonymous. You could have a significantly insignificant strong effect or a statistically significant weak effect. To put it another way, statistical significance is about measuring the accuracy of the model and not the effect of the treatment.
I wish I could take Collagen peptide supplement, but every time I start taking it I fall into a depression. I didn't know that's what was causing it at first, but one day I stumbled upon some information that links taking collagen supplements to depression. I think it was helping my sore elbow, but I didn't see any hair, skin or nail benefits.
I also have had this depression effect, but only from one brand I bought at Costco (possibly Biocell). I’m now taking Skin Rejuvenator with Verisol 10.58 oz | Bioactive Collagen Peptide Powder | Types I and III | Non GMO, Gluten Free Supplement | by Horbaach, with no depression side effect. I also have taken UC-II in the past without issues, but that I think may just benefit joints.
So, they compared soy protein with collagen peptides; but what about collagen peptides in comparison to meat, fish or eggs? Could we get the same anti wrinkle benefits that we do from collagen peptides by eating more meat, fish or eggs?
I took collagen for 4 days after getting my achilles tendon severely injured due to antibiotic use (ciproxin, which notoriously attacks collagen). Well guess what, I feel 80% better than 4 days ago.
Honestly as a protein supplement in conjunction with other nutrient dense protein sources, VP Collagen has a wonderful effect on my performance. Stamina and strength during strenuous heavy lifting and high speed interval sports / training. Also muscle contractions are smooth with quick recovery.
@@Lolipop59 the Vital Proteins brand Collagen Peptides is hydrolyzed and from Grassfed -Pasture raised cows. Costco has on sale with significant discount presently. Some complain of minor headaches because it’s rapidly absorbed, but I defeat that effect with beetroot juice or other antioxidant blueberry smoothie. Start with lower dose than recommended find what works.
I'm still hoping for a diet and supplement video in relation to osteoarthritis. OA is a leading cause of chronic pain in middle age and older people. Its becoming more common (perhaps triggered by an inflammatory processed food diet and obesity?)
I'm much more interested in the use of collagen peptides for joint health and healing than skin health, being a 62 year old hermit with osteoarthritis due to a combination of COL2A1 polymorphisms and hyperhomocysteinemia. Many over 60 would be much the same as myself, and be more concerned with joint and bone health than a few wrinkles. It would be good if your focus and videos could cover a wider demographic, and not overly concentrate on skin health and weight loss. Many over 60 really could benefit from many of these 'longevity supplements' for multiple reasons other than skin health or weight loss. For example I take 500mg of Metformin four mornings a week (not on my three exercise days) even though it's not suitable for weight loss, as my BMI is around 20. I take collagen peptides for joint health and to try to help my arteries recover from homocysteine-driven accelerated athersclerosis. I suppose I see wrinkles as a sign of deeper issues rather than something to fix up without correcting the underlying faults. I see it as a sign of insufficient autophagy as well as collagen dysfunction, with less wrinkles equating to a healthier metabolism with reduced ROS and AGE metabolites and increased glutathione. If hydrolysed collagen peptides are found to have no effect on skin health but are found to support joint health (and eye health) I'll certainly keep taking it. If found to help fix fine wrinkles but no other beneficial effects I'd possibly still take it but wouldn't bother having it regularly, as how well my body 'runs' is more important to me than how I look to others. I have a number of genetic issues and would probably not still be here if I hadn't commenced a one-meal-a-day calorie reduced diet in 1990, at the ago of 30. I only really started on supplements a few years ago and for decades relied on diet and exercise to keep my hyperhomocysteinemia in check and keep my osteoarthritic joints as healthy as possible. In the past few years I've needed to add certain supplements to reverse the homocysteine-driven COPD and osteoporosis and athersclerosis and early-onset Alzheimer's. Hydrolysed collagen peptides seem to have very minimal risk of side effects, and may help offset my COL2A1 polymorphisms. Could you do a more comprehensive video on the use of hydrolysed collagen peptides, in particular the potential non-skin benefits, and also if it can possibly exacerbate some conditions? I have developed some type of hand arthritis since taking hydrolysed collagen peptides, similar to Dupuytren's contracture or 'trigger finger's, and have had lumps form in my palms directly below both middle fingers. It's probably not connected, but I have wondered if the lumps are collagen related and if hydrolysed collagen peptides effect those with collagen gene polymorphisms, such as my COL2A1 polymorphisms, differently than those with healthy collagen processing genes. Any ideas on this topic?
So I plan to continue with the supplements-just like the doc. The scientific evidence is still coming in. And frankly the gummies are delicious. Is my skin just amazing..it’s not bad. The real change (and surprise) was that my knees have not hurt once in 6 months, which is weird. I do a lot of cardio, step and Zumba and I get aching knees sporadically. Nothing, nada, zero pain since I started taking the collagen. The peptides in this particular formulation claim to be for radiant skin only so that was the impetus for me starting them…not joints. Great side effect, though.
@ald6873 It fixes the skin problems older people has. Younger might not notice anything like that. But collagen is in everything in the body. And not enough of that gives you weak tendons, blood vessels, cartilage, and even bone. I think the reason for so much joint problems we have are because we doesn't eat much collagen nowadays. There shouldn't be so many older people needing joint replacement operations, I think.
I take 2-4 servings of collagen peptide powder a day. Yes 2-4. Once I did that (increased the daily intake), my trouble areas, like the right temple of my head/hair, finally filled in. I’m aging in reverse. I swear I look like I’m in my 30s again and the young men think I’m their age. I’ll be 50 in December. Full disclosure - I’m also carnivore. Anywho, I’m finding the older I get the more I should take. I’m completely pleased with the results after about 3 years. I’m afraid to not take it. Also I take both marine & bovine daily.
@@jpintero6330 yes because they’ve done so much good for us 🙄. They would love to perform surgery and prescribe big pharma vs natural healing. We’re in such great health because of them huh? We’re not sick and fat due to their wonderful advice. 🙄. I’m good you go have open heart surgery.
@@LodianRB when I take my large morning dose I pour hot water over it and let it cool then drink it down. I do take doses intermittently during the day I drink it in cold drinks but I had to get a Le Creuset hydration water bottle because it has to be shaken really well to dissolve.
Collagen has changed my 13ry old dog's life. She had a very significant and worsening limp, due to diagnosed arthritis in her elbows. Within the 1st 3 months she showed clear improvement and a year and a half into taking home made collagen, extracted from chicken's feet, she still hardly ever limps at all and takes a couple of hour long plus walks everyday. It has made the whole family happier, especially the doggy, who is chasing squirrels most days.
Glycine is the limiting factor in collagen production for most people, and collagen is only about 20% glycine by weight so supplementing it is a lot of bang for the buck.
@LTPottenger Glycine is used for mutch more than building collagen. Such as building glutathion and much more. It has been estimated that we need at least 10 g of glycine a day. I supplement with hydrolyzed collagen to get all the amino acids for building my own collagen. And with extra glycine because much more is needed. Collagen is the best source for glycine. But you have to eat a lot of it to get 10 g of glycine!
For elderly or those who aren't able to digest protein then collagen peptides are a huge boost. Also if they aren't getting enough protein to begin with. Glycine is a great sweetner
Already consume 180 grams of protein a day for bodybuilding, and adding collagen/glycine combo made my skin look better. If placebo that's fascinating though. We know mechanically that glycine helps either way
Unless I'm mistaken, that study showed that Collagen powder basically works as well as Whey protein powder in regards to muscle synthesis (just no better or worse). That also is reassuring that Collagen can be used as a regular protein powder, whilst also providing other benefits. If anything, this makes me want to double down on it
Collagen has one of the worst, if no the worst amino acid profiles of any protein out there. What study is showing it works as well as whey for muscle protein synthesis?
If I forget to take collegen peptides my lips crack and my skin dries out. To each their own according to their needs. The only other thing I take that has immediate effect is vitamin d+k2. The addition of k2 has brought the dark color back into my hair after just a couple weeks. I'd been almost completely grey and now it's so dark people have asked if I color my hair(which I don't )
I am allergic to whey and started using collagen to as protein supplement. The biggest change i seen is my shoulder pain from being a delivery driver is gone. I bought it for muscle building little did i know it doesn't help with muscle protein synthesis but as a blessing in disguise it helped with my shoulder pain and my skin looks much better. I take 1 serving of 15g collagen everday and will continue it.
People misunderstand placebo. It really dose not matter whether your benefits are due to the product or placebo. If you have the benefits you are successful.
Amazing video! Thank you so much for the review on the different studies; you're really asking the right critical questions here. I think I've seen enough from various Dr. study analysis to judge that, yes, it is worth taking a PEPTIDE supplement. I think there's really a breakdown in understanding from the "team Whey" group of why people are actually taking the peptide supplement.
@@Tacet137 Before after pics are a marketing tool, ESPECIALLY if you get exposed to them without you qctively trying to research them. So it is completely stupid to base yourself on that. And also "not surprised", this person has litterally just read the video title and not seen the content.
@@iDrraaaK right i need to do research into it and get a PHD when in all these years not even one picture to show any difference with all the claims of how eye wrinkles vanished even if its for marketing but still nothing . And i have seen the video which is why i commented regardless he claims there is also evidence to prove in some studies supporting it.. best to use vaseline mate and its cheaper lol
Just like people who eliminate carbs and think they won't get diabetes. Interfering with the cells ability to use carbs can cause insulin resistance. Fats can do this. Protein and fats aren't magical food😅
@@BlueBlossomsBlues Short term different things help. Eating only meat helps some. Dr Brooke Goldner talks about this and now has a raw plant diet. Check her out. Lots of good info in this area that produce long yerm benefit
Hey doc, quick question if you see this and have time- I'm a vegan and was thinking of taking a collagen supplement, but from my quick Google research it seemed like vegan collagen might not really be effective to someone already eating healthy and taking a protein supplement. Any thoughts or ideas about this?
Comparing collagen to soy protein may not be a great comparison. Soy may not be as bioavailable, etc. It should probably be compared to something like whey protein.
The study in question only provided one does of collagen/whey and then they measured the results 5 hours later. This is not a credible way to assess the effect on connective tissue, either in terms of time or loading (especially if you believe Bruce Ames' theory on Nutritional Triage). The most obvious issue to anyone who does resistance training is that the turnover of ligament tissue is far slower than muscle tissue and typically it takes ~8 weeks to see ligaments remodelling due to regular loading, whereas muscle begins the process immediately.
I have yet to get some clarification on this topic, but are the benefits of collagen supplementation specifically due to the peptides or are the primarily due to glycine supplementation or is it a combination of both. There's studies on glycine supplementation with similar effects and studies on collagen peptide supplementation but I have yet to see a study that compares the two, or some kind of analysis on this. Please send me any sources on this if you find it! Are there are studies out there comparing the effects of glycine supplementation vs collagen supplementation? Would like to hear people's thoughts on this!
I bought collagen on a whim because it was half price. Added it to my routine with no expectations. The RU-vid channels I follow say it does nothing special. After a bit over a month I stopped noticing a few things, the mild but chronic discomfort at the back of my right knee from an injury and tendonitis hip pain from overuse at work. The hip still flares up occasionally, but the knee has completely resolved. I think people who experience a positive response using collagen might generally be older as I'm well past middle age. I still buy it regularly and whenever I eat Vietnamese food my go-to soup is beef tendon Pho.
