The big cursed chest can give weapons of a much higher level than normal, so it's a nice little extra chance at getting it. I chose to farm the guardian's projectiles in the 7-2 crown vault. Had to clear everything up to and including 7-1 with Steroids using the Golden Wrench and a Shovel, getting Heavy Heart along the way, then I grabbed a weapon just before diving into 7-2 and made a rush for the vault. It took only a dozen weapons before I got the drop. I keep it on Melting for explosive runs. When you have 5 HP max, you don't care if nuking something gets you down to 4 HP.
Christ, knowing how those purple crystals @ 10:27 can just telefrag you at any moment if you manage to stick close enough for too long, AND the Golden Nuke Launcher is sitting RIGHT THERE?
