In Pharmaceutical Continuous Manufacturing (PCM), technical solutions ensuring critical quality attributes for content uniformity (CU) and unit dose exist for on-line, in-line, and at-line measurements. What is the best way to integrate PAT-based devices, to select sensor technologies; what best-practice solutions exist to avoid complexity in Overall Equipment Effectiveness (OEE)? This webinar will address how to overcome operational challenges-providing an overview of the current state of this technology and its impact on control strategy and real-time release (RTR).
CU assurance within a PCM process
Common approaches to assure content uniformity for tablets
Control Strategy
Impact and examples of control strategies for content uniformity.
Current technical solutions
What built-in or auxiliary equipment is on the market; how to specify solutions, and what is missing.
Sensors
What sensor technologies are applicable and where are they most effective: in-line, online, at-line.
RTR strategy
A review of elements that influence the control strategy for any PCM system, and alternative solutions.
7 авг 2024
