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Penicillin Mechanism of Action animation video 

Pharmacology Animation
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Penicillin pass through porins of gram negative bacterial cell wall. The penicillin then binds to penicillin binding protein linked the cell membrane to be activated. Active penicillin binds to and inactivate transpeptidase enzyme. As a result peptidoglycans NAM and NAG sugars are not cross-linked and the cell wall collapse

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28 дек 2017

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Комментарии : 91   
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
Dear friends, a new comprehensive animation video titled "Antibacterials" was uploaded at this channel. I would be pleased if you have a look at it and send me your feedback
@christinbendorf92
@christinbendorf92 Год назад
Tetrapeptide side chains are attached to NAM not NAG
@masoomesadraei6695
@masoomesadraei6695 3 года назад
I was struggling to understand it with the teacher's paper.. But you simply explained everything in 3 minutes Thank you
@free_at_last8141
@free_at_last8141 6 лет назад
Great overview of the subject, thanks for posting this.
@washimchowdhury2524
@washimchowdhury2524 2 года назад
Quite a good animation. Quick and on point! Thank you
@aliramadan3870
@aliramadan3870 3 года назад
Tetrapeptide is attached to NAM These Tetrapeptides are linked together by pentaglycine cross-link with the aid of transpeptiase ( penicillin binding protein ) and Penicillin inhibits this enzyme .
@FIFANATICS
@FIFANATICS 2 года назад
Yes, this is correct though in one book I'm reading, it says pentapeptide instead of tetrapeptide
@ForeignerD
@ForeignerD 3 года назад
Clarifies very well, thank you
@pnrking
@pnrking 2 года назад
Really high-quality content and lessons Appreciate that 🙏🏻❤
@basrapharmd3320
@basrapharmd3320 4 года назад
Keep it up... V precise and simple explanation.. ♥️
@NQX10
@NQX10 6 лет назад
Amazing, thank you!
@marksteve8373
@marksteve8373 4 года назад
Great explanation! Thanks you :)
@Daydreamer-qg7zv
@Daydreamer-qg7zv Месяц назад
You simply explained it in just 3 minutes hats off to you❤
@MD-qy4fo
@MD-qy4fo 11 месяцев назад
Very simple and very well explained.Thanks.
@user-fl9it7ie2c
@user-fl9it7ie2c 9 месяцев назад
thx a lot for your compact lecture. My knowledge belongs to you
@gjzztrrettmmggrrertzhgyena4950
@gjzztrrettmmggrrertzhgyena4950 4 года назад
Great efforts..💖💖💖💖💖 Thanks Sir💦💦💦💦
@abal-ashrafaffan3503
@abal-ashrafaffan3503 4 года назад
Very short and precise.. thanks much
@ghaziturki9756
@ghaziturki9756 3 года назад
Excellent work 💞💞💞💞💞
@thousifbanu7485
@thousifbanu7485 5 лет назад
Gud explanation
@shortsfootball360
@shortsfootball360 6 лет назад
Great!!!
@shadeeduliqaab
@shadeeduliqaab 3 года назад
Jazak Allahu khayran😍🥀
@omarafaneh13
@omarafaneh13 5 лет назад
دكتور جهاد ارجو الترجمة للغتك العربية هناك ما لا يقل عن اربع مئة الف عربي قد يستفيد كثير منهم من هذا الجهد المبارك.
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
ان شاء الله المرحلة القادمة تكون الترجمة الى اللعة العربية يا عمر
@omarafaneh13
@omarafaneh13 5 лет назад
فتح الله لك من خيره وبركاته.
@marksteve8373
@marksteve8373 4 года назад
@@omarafaneh13 You ought to know English in order to truly comprehend these concepts~
@nourai5653
@nourai5653 4 года назад
👍🏻👍🏻 Great
@lunaanika5962
@lunaanika5962 2 года назад
Wonderful 👏👏👏
@thabisonyawo500
@thabisonyawo500 6 лет назад
very useful video thanks
@kashifofficial5820
@kashifofficial5820 2 месяца назад
Absolutely stunning Allah bless you
@dawarhub4682
@dawarhub4682 9 месяцев назад
Very informative ❤
@sumitsaini153
@sumitsaini153 3 года назад
Quite good 👍
@misse2359
@misse2359 7 месяцев назад
hocam gercekten cok aciklayiciydi. Ellerinize saglik
@Hassanali55880
@Hassanali55880 Месяц назад
Amazing thank you
@arjunraj7577
@arjunraj7577 5 лет назад
very much helpful
@perdantpersonne1279
@perdantpersonne1279 2 года назад
Thank you sm for this video🤍
@daouduni6006
@daouduni6006 6 месяцев назад
Thank you so much 🙏🏻
@arry9396
@arry9396 2 месяца назад
Thank you so much❤
@Cheeruppy6166
@Cheeruppy6166 14 дней назад
Thank you very much helpful
@ArmedBubble15
@ArmedBubble15 4 года назад
Thankyou!
@Kyle-vp2dk
@Kyle-vp2dk 2 года назад
Correction - PBP's are transpeptidases that link different segments of the peptidoglycans together.
@BadBoy-uj3gg
@BadBoy-uj3gg 2 года назад
Thank you 🙏
@farahnaz1581
@farahnaz1581 3 года назад
nice explaination
@anita26069
@anita26069 3 года назад
thank you!!!
@btslove_forever
@btslove_forever 3 года назад
Nice video tq sir
@Official21708
@Official21708 2 года назад
Thanks you sir 😊
@obioraokafor831
@obioraokafor831 10 месяцев назад
Perfection
@mariamgad284
@mariamgad284 4 года назад
But the chains of amino acids are between NAMs not NAGs..
@viral_memes4u
@viral_memes4u 2 года назад
Yes obviously
@viral_memes4u
@viral_memes4u 2 года назад
Absolutely right
@Tina-bo1sf
@Tina-bo1sf 11 месяцев назад
Make your own natural medicine. We know the mechanism of action. Find the plant that does the same and they can kiss our ars.
@kundankumar-dj1qs
@kundankumar-dj1qs 6 лет назад
Nice
@mmproduccionmusical1350
@mmproduccionmusical1350 Месяц назад
could you write the source/journal article where you found this information?
@roselinrathinasamy1411
@roselinrathinasamy1411 Год назад
👍🏻👍🏻👍🏻
@user-if8my6hm6r
@user-if8my6hm6r 4 года назад
isnt pentapeptide and cross linking located betw NAM?
@Ausnapify
@Ausnapify Год назад
I dont know
@sheryariqbal9697
@sheryariqbal9697 3 года назад
Please add subtitles
@user-yk8tf9ye1u
@user-yk8tf9ye1u 2 года назад
Why 1,3thiazol ring in cephalosporins do anti-MRSA activity
@smsma6655
@smsma6655 3 года назад
جميل
@drmathusingh7601
@drmathusingh7601 3 года назад
5 amino acids chain come from nam( N acetyl muramic acid). Not from nag( N acetyl glucosamine.
@user-cb5su9yt5i
@user-cb5su9yt5i 2 года назад
What is the role of NAM and NAG?
@christinbendorf92
@christinbendorf92 Год назад
Tetrapeptide side chains are attached to NAM not NAG
@ghatrmmobile4137
@ghatrmmobile4137 3 года назад
finE siR 💛💚💙❤🌺🥀🌹
@888167
@888167 5 лет назад
why do the bacteria even have this PBP? Is there any positive function for the bacteria?
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
I hope you will find your answer in the more detailed antibacterial video in my channel. ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Qah8-3QV9uE.html
@JustPharmacology
@JustPharmacology 4 года назад
These protein are not meant for pencillins but it is property of pencillins to bind them and that's why bacteria alter them and acquire resistance
@Travelin_Man1
@Travelin_Man1 3 года назад
One inaccuracy in the video is the representation of PBPs. Penicillin-binding proteins *are* the transpeptidases. They aren't separate molecules.
@hassinayazid99
@hassinayazid99 2 года назад
the cross-linkage is between NAM not NAG!
@PickonesBrainHub
@PickonesBrainHub Год назад
There is only linkage between Nam to Nam
@oliverharris6116
@oliverharris6116 6 лет назад
A Level Biology 4TW
@katetosh
@katetosh 4 года назад
Why does penicillin not work on candida albicans? Is it due to it being made up of Chitin, not peptidoglycan? or is there more to it?
@JustPharmacology
@JustPharmacology 4 года назад
Candida is fungus and cell wall is different, some what more complex ergosterol, glucan and chitin are targets
@MatTroiLuoi
@MatTroiLuoi 5 лет назад
But penicillin doesnt work with Gram negative bacteria
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
Penicillins as a family have gram negative spectrum. I have just uploaded a new video titled Antibacterials, I would be pleased if you have a look at it.
@FIFANATICS
@FIFANATICS 2 года назад
Transpeptidase itself is one of PBPs This guy is tripping
@DrNBShridhar
@DrNBShridhar 3 года назад
Please give permission to use them for education purpose..
@PharmacologyAnimation
@PharmacologyAnimation 3 года назад
You welcome to use them for education purpose at any time
@DrNBShridhar
@DrNBShridhar 3 года назад
Thanks
@user-ti3yf3op4c
@user-ti3yf3op4c 5 лет назад
دكتور اعمل لنا بالعربي او حط الترجمة للعربية جزاك الله خيرا
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
ان شاء الله المرحلة القادمة تكون محاولة التعليق الصوتي باللغة الهربية على الفيديوهات
@user-ti3yf3op4c
@user-ti3yf3op4c 5 лет назад
@@PharmacologyAnimation ان شاء الله
@kyletang7
@kyletang7 3 года назад
The peptide cross-links should be between the peptides coming off of the NAMs, not NAGs. ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-a81nHSqQuvI.html
@projectszymon5591
@projectszymon5591 5 лет назад
why 40 old men prof, sounds like 13 years old girl
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
the narrator is a third year medical student girl
@NearCentury
@NearCentury 5 лет назад
conner hagerman out.
@pathnis
@pathnis 2 года назад
I almost got killed by doctors because of this stupid drug
@tedmcmanus7166
@tedmcmanus7166 Месяц назад
based
@vamshikrishna7491
@vamshikrishna7491 5 лет назад
Wrong mechanism of action
@PharmacologyAnimation
@PharmacologyAnimation 5 лет назад
Why do you think it is wrong mechanism of action?
@anshulsharma7627
@anshulsharma7627 3 года назад
Yuk quality audio
@sadiahaque8389
@sadiahaque8389 2 года назад
Wrong
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