Philadelphia chromosome | Chromosome 9 to 22 translocation | BCR-ABL translocation| CML pathology

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This video talks about Philadelphia chromosome | Chromosome 9 to 22 translocation | BCR-ABL translocation| CML pathology
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Опубликовано:

2 апр 2024

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Комментарии : 18

@YougiTune 2 месяца назад

This was a very succinct and solid video. Thank you for your hard work.

@animatedbiologywitharpan 2 месяца назад

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

@QuranicVlogs786 2 месяца назад

The more complex issue explained very easy. Please sir make easy all lymphomas and leukemias easy

@animatedbiologywitharpan 2 месяца назад

All lymphomas (Hodgkin, non Hodgkin ) , Leukemia etc is scheduled this month and next month. Please stay tuned. Share with friends.

@animatedbiologywitharpan 2 месяца назад

by the way are you a med school student

@QuranicVlogs786 2 месяца назад

@@animatedbiologywitharpan Dear sir what about CNS pharmacology and pathology?

@Kabir_Khayer 2 месяца назад

Thank you arpan da. Good quality good information. Deep 📚knowledgeable

@animatedbiologywitharpan 2 месяца назад

Thanks a lot for the support

@josephhunter1104 6 дней назад

Good channel Dr

@animatedbiologywitharpan 6 дней назад

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

@user-on1ug4ff3i 2 месяца назад

Thanks 😊 Give me the source you used to make this video, a book or scientific research...

@animatedbiologywitharpan 2 месяца назад

Robin's pathology book would be perfect

@user-on1ug4ff3i 2 месяца назад

@@animatedbiologywitharpan thanks

@anmolpardeshi3138 Месяц назад

good video, Arpan. just one clarification: at 1:13/14 you say "BCR gene is highly active that is why ABL leads to ABL kinase...." but its not clear why transcription of one gene leads to product of another gene. I'm assuming its a mistake?! if so pls clarify. thanks.

@animatedbiologywitharpan Месяц назад

Sorry for the confusion. The BCR-ABL fusion protein results from the translocation of the BCR gene to the ABL gene, leading to increased kinase activity. The close proximity of the BCR gene to the ABL gene may alter the conformation of the ABL kinase domain, enhancing its expression and activity within the fusion protein.

@animatedbiologywitharpan Месяц назад

Its the BCR enhancer region which is really strong , enhancer can act on any nearby location to increase transcription .

@animatedbiologywitharpan Месяц назад

Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.

@anmolpardeshi3138 Месяц назад

@@animatedbiologywitharpan I dont think that was the point you were making because during that statement the BCR-ABL in the diagram were separate. but thanks for replying.. may be it be it will be more clear.