POLARIX trial: Is Pola-R-CHP effective and safe in elderly patients with DLBCL? 

During the 17th International Conference on Malignant Lymphoma (ICML), the Lymphoma Hub spoke with Hervé Tilly, Centre Henri-Becquerel and University of Rouen, Rouen, FR. We asked, Is Pola-R-CHP (polatuzumab vedotin plus rituximab, cyclophosphamide, doxorubicin, and prednisolone) effective and safe in elderly patients with diffuse large B-cell lymphoma (DLBCL)?
Polatuzumab vedotin in combination with R-CHP was granted FDA approval for patients with untreated DLBCL in April this year. Tilly discusses results from a subgroup analysis of the POLARIX trial (NCT03274492), reviewing efficacy and safety in elderly patients with DLBCL. He focuses on the primary endpoints and important adverse events.
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