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Primary hemostasis | Advanced hematologic system physiology | Health & Medicine | Khan Academy 

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During primary hemostasis, a platelet plug is formed to rapidly stop the initial bleeding after injury. Learn about the different steps involved in primary hemostasis: vasoconstriction, platelet adhesion, activation and degranulation, platelet aggregation. Created by Gricelda Gomez.
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3 июл 2024

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Комментарии : 84   
@MonnieMoo318
@MonnieMoo318 9 лет назад
THIS VIDEO IS ABSOLUTELY AMAZING!!!! I actually am understanding!! :D THANK YOU KHAN ACADEMY!! :D
@naidoi1
@naidoi1 9 лет назад
I absolutely love khansacademy ☺️☺️☺️
@mohamedjatte9145
@mohamedjatte9145 27 дней назад
Thank you for your simple explanation
@safirazed7375
@safirazed7375 10 лет назад
Awesome! Thank you so much!
@LD-jp3iu
@LD-jp3iu 7 лет назад
Great explanation. Really helped explain the details of primary hemostasis from First Aid 2017
@noorabd5691
@noorabd5691 5 лет назад
Really thank u... God bless ya❤️❤️
@user-uu3xy5ri1p
@user-uu3xy5ri1p 5 лет назад
thank you khan academy, for helping me with almost every exam TT
@ahmedgamaleldeen8451
@ahmedgamaleldeen8451 9 лет назад
Excellent !
@cormacdoyle3435
@cormacdoyle3435 6 лет назад
This video is so helpful, thank you
@tonyejack2069
@tonyejack2069 7 лет назад
i love this video thanks!!!!
@minhlucnguyen7614
@minhlucnguyen7614 4 года назад
Thank you so much for blowing up my mind, this video is super amazing and easy to be understood!!!!
@majedsaeedy1910
@majedsaeedy1910 2 года назад
Amazing explanation, clear and informative diagrams. I was watching a lecture at my university and didn't really understand primary hemostasis, but this video really cleared it up.
@fanvd
@fanvd 8 лет назад
thank you!
@unrivaled37
@unrivaled37 9 лет назад
Thankyou!
@pitiful_sentence
@pitiful_sentence 7 лет назад
THANK YOU!!!
@rahmiaziza4698
@rahmiaziza4698 4 года назад
this is really helpful! thanks a lot 😊
@yashika5006
@yashika5006 6 лет назад
These are really helpful......thank you
@maryannekastner
@maryannekastner 9 лет назад
great video!!
@demonskwirl9462
@demonskwirl9462 2 года назад
this is outstanding. very concise, understandable, easy to remember
@asmahaque8558
@asmahaque8558 4 года назад
YOU ARE BRILLIANT!
@PinkPeony21
@PinkPeony21 9 лет назад
Fantastic video! Thanks
@user-zz1qd1pe7l
@user-zz1qd1pe7l 2 года назад
Great explanation. Thank you!
@a.s.america
@a.s.america 7 лет назад
great! i almost got it! thank you
@sarajade1322
@sarajade1322 7 лет назад
great work ..
@mohamedalimegahedahmedrash3822
THANK YOU
@nazmaahmed1544
@nazmaahmed1544 7 лет назад
Thank you
@ALIMAX20072
@ALIMAX20072 9 лет назад
i wish u were my professor :(
@nativedamascus8819
@nativedamascus8819 5 лет назад
Great work thank you
@bahiachibi895
@bahiachibi895 2 года назад
Wonderful amazing thanks
@jmoney8630
@jmoney8630 5 лет назад
I don't know why people are complaining about the voice over. I thought it was perfect. She was talking like an actual person does when they are talking to you. And personally, that helps me listen better. Would people rather it be completely monotone? To each their own I suppose.
@tahirakhtarvlogs5637
@tahirakhtarvlogs5637 4 года назад
Thank you 🙏
@reemalhazza4868
@reemalhazza4868 4 года назад
Thank you and love you 😍
@nikolaoskormpis3511
@nikolaoskormpis3511 3 года назад
Really good explanation, thank you
@nadeemrabi647
@nadeemrabi647 8 лет назад
I love you !
@gangsardamai8139
@gangsardamai8139 4 года назад
thankzz
@hudapediatric3492
@hudapediatric3492 8 лет назад
nice helpful vedio thanks alot
@kaelashawa8305
@kaelashawa8305 7 лет назад
thankyou
@mrcharlesjohnson
@mrcharlesjohnson 5 лет назад
Str8 fantastic video thnx so much for explaining this in a simple manner
@alaaelshiekh3064
@alaaelshiekh3064 6 лет назад
great vedio
@MrShishpal
@MrShishpal 3 года назад
Great information
@lovely-zg6di
@lovely-zg6di 5 лет назад
y are amazing tnx
@abrardesrt
@abrardesrt 6 месяцев назад
pravo... thx thx thx ❤❤❤❤❤
@amna7629
@amna7629 6 месяцев назад
Gorgeous 🤝🏻✨
@kv9430
@kv9430 3 года назад
thank you for your sharing ms, this is best, i really analyze the process of primary hemostasis, thank you, i hope for you response 😇
@jowanismail1942
@jowanismail1942 4 года назад
Nice one 💕
@michaelgilman4068
@michaelgilman4068 3 года назад
Thanks pretty darn good overview. My Lippincott Pharmacology text fills in some details but your narration and illustration make the concepts and substances a bit easier to latch on to...One small note of criticism, meant constructively, the "hole" in the vessel is called the lumen.
@1412Z
@1412Z 2 года назад
thank you! very helpful video, i recommend also watching the 2ndary hemostasis video by Khan Academy
@rubaali7886
@rubaali7886 Год назад
I can be clear with u guys I wouldn't make it through one day before exam without u 😭🙏
@laboniroy-ed8qp
@laboniroy-ed8qp Год назад
Best
@mandisangema2568
@mandisangema2568 3 года назад
You saying fibrinogen leads to platelet aggregation? Doesnt have to be cleaved to fibrin by thrombin first?
@mikeearls126
@mikeearls126 2 года назад
its cool to learn here definitely....but the high speed video and high speed talking of a person who knows everything about the topic makes learning harder (have to constantly stop video) teaching is not just spewing out stuff as fast has humanly possible....but actually considering who is watching....of course IMHO
@priyankamidha5071
@priyankamidha5071 4 года назад
Thank you so much, amazing video. I have a question if someone can help me with it - When an injury occurs, why do we only lose NO and prostacyclin (vasodilators) with the blood and not the vasoconstrictor, endothelin?
@rahmiaziza4698
@rahmiaziza4698 4 года назад
because the winner is endothelin :) I mean like vasoconstrictor more stronger while injured, so the vasodilators gonna fail with it. Hope it's gonna help u,guys😊
@sofiajadez7126
@sofiajadez7126 5 лет назад
thank you!!!!
@alexcoreablecoreable
@alexcoreablecoreable 7 лет назад
for the last part of this video, isn't it fibrin instead of fibrinogen? i thought fibrinogen needs to be converted to fibrin and then it can form cross-linked mesh?
@nbgoodiscore1303
@nbgoodiscore1303 5 лет назад
I know I'm late but fibrin only exists in secondary hemostasis.
@blackyrocky7438
@blackyrocky7438 3 года назад
First response to vascular injury is vascular spasm or vasoconstriction to reduce bleeding. Then platelet plug, aggregation, and thrombus form. Injured or damaged endothelial cells release endothelin which will act on smooth muscles to contract and ultimate goal will be vascular spasm. Particularly endothelin will trigger release of calcium in smooth muscles which will cause contraction
@sharonzell2308
@sharonzell2308 8 лет назад
I can get sound on other videos but not the primary and secondary hemostasis?
@leopoldoansantos
@leopoldoansantos 5 лет назад
Great, thank you! What is the name of this software?
@GigglrTv
@GigglrTv 7 лет назад
Hey, do u com(ment) here often?
@AIJ101
@AIJ101 3 года назад
Great video however I'm not an engineer but if a bridge falls out or half of it does it would be common sense that you don't use the bridge because the integrity of the bridge is no longer intact
@sandervdcp3513
@sandervdcp3513 2 года назад
what is the program for the drawings?
@davidt8274
@davidt8274 8 лет назад
The alpha granules contain fibronectin, not fibrinogen - fibrinogen itself has to be activated by thrombin to become FIBRIN and is stickier - it polymerises with other fibrins and stuff, and only binds to fibronectin when mediated by factor VIII. Fibronectin... don't polymerise, they bind to fibrin when Factor VIII comes into play and catalyse the process (factor VIII stabilises fibrin and 'contracts' it, closing up wounds), Fibronectin mainly binds cell membranes through connecting with integrin molecules, which means it binds cells to cells. Platelets basically start working on long term healing the moment the are activated, but is relatively inefficient until fibroblast cells come in and form huge amounts of connective tissue etc.
@sofiamosca2714
@sofiamosca2714 6 лет назад
Alpha granules contain both: fibronectin AND fibrinogen
@firstnamelastname5474
@firstnamelastname5474 3 года назад
They have both, actually.
@gabrielsanchez8501
@gabrielsanchez8501 7 лет назад
Fibrinogen is produced by the liver. I think you meant to say "Fibronectin".
@Dr.Ankesh
@Dr.Ankesh 7 лет назад
fibrinogen and fibronectin both are present in alpha granules of platelets
@micahrapata5085
@micahrapata5085 8 лет назад
So just to clarify, does fibrinogen not fibrin aggregate platelets via their activated 2b/3a receptors?
@mohammedabdullah5989
@mohammedabdullah5989 2 года назад
Fibrinogen aggregates the platelets via their receptors. Fibrin is formed from fibrinogen by thrombin.
@dhooy7150
@dhooy7150 8 лет назад
I don't understand the purpose if vasoconstriction as a result of damage to collagen. Wouldn't this cause more blood to be lost?
@AssassinNasa16
@AssassinNasa16 8 лет назад
Vasoconstriction will increase the flow resistance therefore reducing the flow of blood to the wound site.
@jannasalam
@jannasalam 7 лет назад
the content is good but the voice over is so poor!
@abdullahmohammad6803
@abdullahmohammad6803 6 месяцев назад
No its not
@ramzehythmoni1777
@ramzehythmoni1777 6 лет назад
I think ..stop saying that .. Plz .
@lisadonayre6654
@lisadonayre6654 6 лет назад
The voiceover/dictation of the topic is SO distracting... still, helpful information..
@muriellejean-baptiste7511
@muriellejean-baptiste7511 9 лет назад
too fast, too fast! lol but still helpful
@graciechandlee8879
@graciechandlee8879 8 лет назад
your constant pausing in your sentences is killing me.
@alaaelshiekh3064
@alaaelshiekh3064 6 лет назад
no she is cute u fuck
@Mrscarfire1
@Mrscarfire1 6 лет назад
It is a very good video but please, please, please stop moving the cursor around when you are not writing! You wiggle it around and shake it constantly, it is distracting and annoying. I would quit watching this video except it was assigned by my instructor.
@anglcasncn
@anglcasncn 6 лет назад
You're so hard to understand it makes me sleepy. Prolly because of how you talk. But thanks for the effort
@BrunaNathaly
@BrunaNathaly 8 лет назад
thank you!
@Marlencheeen
@Marlencheeen 7 лет назад
very good job !!!
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