Hi Adrian,Thanks for the comment. If you refer to my following youtube video it will give you a comprehensive understanding as to how I arrived at this formula including the number 6 you are referring to. Hope this helps.
Use the first formula if you have been taught that 1NADH produces 2.5ATP and 1FADH2 produces 1.5ATP when connected to the electron transport chain. Use the second formula if you have been taught that 1NADH produces 3ATP and 1FADH2 produces 2ATP when connected to the electron transport chain. Hope this helps clarify which formula to use. Regards, Wonders of Chemistry
@@wondersofchemistry Yes Thankyou So Much For Your Reply But Can You Clarify My One more Doubt Can i use this formula to calculate how many atp formed from ketogenesis(I.e From molecule Of Acetyl CoA)?
The formula(s) are designed only to calculate the total yeild of ATP for saturated even numbered fatty acids. So just to clarify, you want to calculate how many ATPs a ketone such as acetoacetate could yield during ketogenesis... is that correct?
ok ... So lets assume each of the two acetyl coAs that made up acetoacetate where liberated and used within the citic acid cycle of mitcondria within the peripheral tissues including that of the brain (recall the liver cannot metabolise ketones) ... each acetyl coA would generate 1GTP = 1ATP, 3NADH = 3 X 2.5ATP = 7.5ATP and 1FADH2 = 1X1.5ATP = 1.5ATP. Adding all these up gives 10 ATP per acetyl coA. However, acetacetate breaks down to give 2 Acetyl coA's. Therefore acetoacetate can generate a total of 20ATP. I hope this helps abswer your question. Note my calculations are based the following assumptions 1GTP will give 1ATP, 1NADH will give 2.5ATP and 1FADH2 will give 1.5ATP.
Hi Camille, apologies for the late reply to your question. Please click the following link to my youtube video which explains how the numbers for each of the two algorithms are derived. Be a little patient and watch the whole video as this will really help with your understanding. ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Erfr7i04WgM.html
The first formula assumes that for every NADH produced this will translate into 2.5ATP and for every FADH2 this will translate into 1.5ATP. The second formula assumes rounded up figures 3ATP and 2ATP respectively. Older text books tend to use the rounded up figures.