this video describes the allosteric and transcriptional control over the glycolysis pathway.It also tells you how glycolytic flux is regulated depending on the energy demand
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Hexokinase regulates glycolysis by phosphorylating glucose, trapping it within the cell. It is inhibited by excess glucose-6-phosphate, preventing overactivity. Insulin activates hexokinase, enhancing glucose uptake and glycolysis in response to high blood glucose. Tissue-specific isoforms and kinetic properties further tailor glycolysis regulation to the needs of different tissues.
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