Regulation of glycolysis and gluconeogenesis | Biomolecules | MCAT | Khan Academy 

because becky from alpha delta pi is smarter than you 💅🏽

+Kevin Miles It was just an analogy. We all know this.

Nice flex, and all true, but this is intended to get med-school hopefuls to the correct answers on a standardized test. Le Chat becomes intuitive, almost second nature, after the minimum two years of chemistry courses pre-med students must take. Because of this intuitiveness, Le Chat becomes a useful thought model upon which "the gist" of these pathways can be thought about in a manner that gets students to the correct answer on the "high yield" questions of a test like the MCAT. Yes, there may be a question or two that requires the deeper knowledge you're promoting here, but far more questions will cover metabolism at a higher level -- yielding examinees a higher proportion of available points -- where this video's analogy is helpful enough, albeit incorrect or ill-advised. For future examinees, spending the extra time on the details you're discussing takes time away from studying the several other topics on the exam, and to gain one or two more correct answers on metabolism at the expense of several or more _incorrect_ answers in other areas makes these deeper topics of metabolism "low yield." I know, it's frustrating to see something you like distilled in such a way, but this is for test takers, and standardized test taking is often not a measure of deep functional knowledge, it is a measure of strategy (and often times wealth

This is missing the point, Any chemical reaction in a system (even those in a steady state) will have a theoretical equilibrium point. When the reactants shift, this will change the equilibrium point, regardless of whether the system is at equilibrium *at that instant*. The equation will shift the same as if it were at equilibrium. Now I would even go so far as to say that the slow regulation is a function of LeChatelier's principle, since even transcription is, in essence, a chemical reaction. The systems get larger, with many reactions all simultaneously being shifted in equilibrium one way or the other, but this action is all resolved into many examples of simple shifts in equilibria, otherwise known as LeChatelier principle.

LOL facts

+Medina Sareini In glycolysis, any glucose that goes past the G6P is considered "irreversible" until it becomes pyruvate. The liver is able to make pyruvate into Glucose again via Gluconeogenesis. In doing this, it can then have a "second chance" at being converted into Glycogen via Glycogenesis. So if you have high ATP, your body will take the Glucose it has, and convert it into Glycogen. But anything at the pyruvate level will be reconverted into Glucose so it can then be stored as well as Glycogen. Hope that helps.

Insulin promotes glycogenesis - storage of glucose in glycogen form to lower blood glucose levels. Glycolysis will also occur because we need to break down the glucose for energy and other metabolic pathways in the body. Glycogenolysis (which is the opposite of glycogenesis breaks down the glycogen stores when blood glucose levels are low (activated by glucagon). Gluconeogenesis occurs when there is a lack of glucose and the glucose stores are depleted, so it makes glucose from non-carbohydrate precursors such as lactate, pyruvate, some glucogenic amino acids etc. So yes you would store it but you will also break it down for energy purposes.

Nis Cen Check your logic. "Breaking down" glucose would not "increase the amount in the bloodstream" because you're breaking it down (glucose -> pyruvate -> Acetyl CoA -> ATP)...I think you're getting "glucose breakdown" mixed up with "complex carbohydrate breakdown". The only carbohydrates that would yield more glucose from breakdown would be complex carbohydrates (but that doesn't happen intracellularly anyway). Gluco-neo-genesis is the making of new glucose (from not-glucose), which would put glucose into the blood from whatever protein/fat sources. Glyco-lysis is that: breakdown of glucose. Logically, with too much glucose in the blood, you'd want to put it away ~from the blood~ by A: storage (as glycogen or fat) as well as B: burning it (by breaking it down into usable energy/smaller building blocks). The actual storage process of glucose into fat requires building blocks smaller than glucose, so it actually requires glycolysis in order to make enough citrate necessary to generate triglycerides. Insulin promotes all of these.

Milan Stankovic it’s all about balance & get exercise.., & with fruits & veggies, u have fiber & fiber slows down the absorption of sugars so you’ll be fine

its a person xD

Cus ur gay

Insulin DOES promote Glycolysis (Glucose breakdown) . It does it by activating PFK-2 (Phosphofructokinase-2) which results in increased concentration of Fructose 2,6-bisphosphate which in turn stimulates PFK-1. btw, insulin activates PFK-2 through Receptor Tyrosine Kinase (RTK) and activation of Protein Phosphatase (via PI3K) which dephosphorylates the PFK-2/FBPase-2 bifuctional enzyme complex

+Henry Ades "Sha" ... En francais, on prononce le "ch" comme "sh"