This guy is the only reason I'm getting through med school....lol. I just want to know who the 21 people are that didn't like the video!!!!!!!!! (probably faculty members seeing their jobs going away)
Zach, I'm a Term 1 medical student and I just want to stop by and tell you how much I appreciate all your videos. I'm on my last week of the first term and we have our CPR2 exam coming up and your videos have clarified so many points in their lectures. A year ago my father died from a massive pulmonary embolism. As you can imagine, its very difficult for me to listen to these concepts and understand just how much he went through during his final moments. He's my sole motivation for becoming a doctor. I hope I can make him proud in the years to come but as of right now I've been able to accomplish that thanks to you and your channel! I look forwards to watching many more of your videos throughout my medical school journey. Thanks again!!!
Thank you so much. I'm in dedicated right now studying for Step 1, and this is the first time I've ever understood ventilation and perfusion. Ever. I cannot thank you enough.
OMG!! This is absolutely fantastic!! If you understand the basic concept - like what you are explaining, you can never get lost anywhere in Respiratory Pathophysiology!! Thank You Very much!
best teacher ever! seriously thank you for helping me get through my physio in the course of 6 weeks -_-...yes 6 weeks. I learn more from you then my professor so I stay home and study my chapters with ninja nerd. Thank you
+Breeann Barcelona wow! Thank you for the kind words they mean so much. You are a brave individual for taking a physiology course in six weeks. I hope these videos really helped and I wish you the best of luck in your future endeavors.
Ninja Nerd Science sir iam really thakfull for your teaching....earlier hardly i studied that toowith fear...afteri started watching ur videos,iam studying out ofjoy now sir
Respiratory Physiology has always been a nightmare for me to study until I came across your lectures. Thank you so much for taking the time to explain intricate information to such simplicity. Keep up the awesome work.👏👏👏
This man is a genius he teaches and explains things that you didn't understand in your past physiology lecture in class. God richly bless🙏 your for passion and sincerity to let every student comprehend.
Wow! this is exremely wonderful. Thanks alot, you made this things very easy. Point of correction- The lower zones of the lung ventilate better than the upper zones and the middle zones have intermediate ventilation.
At time 27:30, you said that ventilation decreases from apex to base, but actually it increases from apex to base of the lung. Perfusion also increases from apex to base, but much more significantly that we have a lower V/Q at the base.
@@BlaackAnchor is it because at the end of expiration, the FRC at the apex area is more than the bottom, so the ventilation at the apex is considered lower?
I feel like you should have emphasized that the smooth muscle in the arterioles contracts and relaxes because capillaries dont have smooth muscle and so the illustration can be misleading.
Im beginning to think the people who dislike this video are the professors who "teach" the subject but suck at explaining it. What a bunch of haters. You rock dude keep it up!
Hello u said that ventilation is better in the top(apex ) of the lung ,but actually it should be decreased bec all books said that lower zones of the lung ventilated better thant upper ,i wish u explain!! + ur the best in explaining physiology
The ventilation being talked abt is in the alveoli and not outside the alveoli..the ventilation will be more at the base but that phenomenon is applicable to the outside of the alveoli
@@rachellugtu2776 if the perfusion is lowest at the apex then whould the apex of the lung not try and match the ventilation therefore at the top of the lung would have a high ventilation?
There is an error: ventilation is higher at the base than at the apex because of increasing compliance. The V/Q ratio is biggest at the apex because at the apex: Q higher is relatively to V. V/Q ratio is lowest at the base because V is higher comparatively to Q.
wanted to let you know Ninja Nerd. you have helped me so much man. literally could not get this down until i watched your video a few times. working toward the Flight Paramedic Certification which, there are no classes to teach the material just a book. so just wanted to let you know. HUUUUGE Help!! couldn't have done it without you.
Hey Zach, great video but wouldn't V AND Q be greater at the base compared to the apex (~28:00)? Pa > Pv > PA in Zone 3 so arteriolar perfusion pressure leads to good blood flow. For Ventilation, alveoli at the base have higher compliance and we would see an increase in ventilation for Zone 3 as well. Overall the the increase in Q > V so V/Q is decreased even though both are increased
Sir, you teach us from the root of the topics that i love... Sir can u make a video on chest x-ray..there are many lectures on xray but all are boring....
Untill i saw ur lectures for the God sake i really hate physiology Our lectures would say anything clearly They even don't knw wht rubish they were teaching us Ur excellent 💯 teacher U were helping all 1st yr students sooo much ☺thnk zach sir
Correction: Type 1 Alveolar cells make up 40% of the alveolar cells in number and Type 2 make up 60% of the cells in number, however the type 1 alveolar cells take up approx. 95% of the space and type 2 approx 5% of the space Correction 2: Nitric Oxide causes smooth muscle relaxation by activating guanylyl cyclase, increasing cGMP concentrations in the smooth muscle cell, activating cGMP dependent protein kinase which in the end phosphorylates and activates Myosin Light Chain phosphatase which leads to smooth muscle relaxation. It is not dependent on K+ efflux.