Sequencing Novel Therapies in Colorectal Cancer 

A roundtable discussion, moderated by Shikha Jain, MD, FACP, discussed the treatment sequencing, management, and future directions of advanced colorectal cancer, as well as relevant clinical trial data from the 2024 American Society of Clinical Oncology Annual Meeting. Dr. Jain was joined by Suneel Kamath, MD; Arvind Dasari, MD, MS; and Sakti Chakrabarti, MD.
In the fifth segment of the roundtable series, the panel explores the impact of ctDNA in adjuvant settings, sequencing challenges for therapies like fruquintinib and TAS-102, and the transformative potential of KRAS-targeted therapies such as sotorasib.