SHOW NOTES 📝 0:00 Welcome, introduction, Dr. Church CV 1:30 Tweaking biology with a 30,000-foot view of history 3:01 "Point of awe" discussion; species extinction, DNA, and carbon sequestration 5:01 X-ray crystallography breakthrough conversation 7:18 Genome sequencing; founding early companies; data interoperability via blockchain 10:31 More on privacy and access controls; UBI mention; data silo and homomorphic encryption 13:12 CRISPR/Cas9 conversation; "eighth wave"; picking the best sequencing 15:53 TAL still in use; next-generation target is multiple sites at once; off-target and on-target, avoiding off-target 18:31 Use of computational biology in genetic engineering; inspiration of outliers 20:14 Vaccine and cognitive enhancement conversation 22:35 Neuroplasticity and neurodegeneration importance; MICrONS Project reference, reconstructing connectomes 25:38 Importance of knowledge preservation; "it takes a lifetime to get to a point of competence"; reversing the planned obsolescence of aging by actually staying younger 29:12 More on longevity and Dr. Church's work at the Wyss Institute; "atomically precise engineering at scale" 33:58 Managing a 100+ person lab and design conversation; failing fast, groups of three, interdisciplinary teams; importance of both co-mentorship and entrepreneurship 38:28 Keeping up with all the scientific developments 40:10 Information dissemination in the lab and educating the general public; pgED.org mention 42:53 Workflow design in the lab; alumni network, principle of patience 44:50 Simulation Q1: What is a core driving principle in your life? 46:30 Simulation Q2: Do you think we live in a simulation? 47:25 Simulation Q3: What is the most beautiful thing in the world? 48:26 Thanks and appreciation, closing comments What are your thoughts about our future with synthetic biology & how to maximize human potential? Let us know in the comments below!
also please don't feel like you need to provide lengthy summaries to the answers of the interviewee. George is great at explaining, and transferring knowledge on a technical subject, you are a layman on the subject, let him transfer the knowledge, you are making it confusing buy trying to summarize this often incorrectly. something of the Sacha Baron Cohen about the interviewer.
sorry but one of the worst interviews I've ever seen, it was uncomfortable to the extreme, trying to concentrate on the subject and his views became somewhat imposible over the painful interviewer. I am very surprised george did not pull the interview, The interviewer even seemed to refer to george in the past, third person in front of him, not something I have ever hear someone say , period. i.e. (interview said "george was")! On a positive help point, please have succinct (10-15 word clear rehearsed questions),try to link the questions so they flow, make eye contact when asking them, listen to their views and answers. basically have the mind set of finding out how your child did at school today, let them talk and ask friendly but probing short questions. not all bad (he clearly had done some research) but close.
Yes Dr. Church is truly a leader in the field of biotechnology, genomics, and really at the pioneering edge of knowledge as we know it. Let us keep pushing with him and others.
Love the interviewer, so passionate, so genuine and with awesome questions. Love the "...maxed out all his attributes.." quip, so true, George Church is truly an inspiration.
Yes. Much like Apple has IOS (iPhone Operating System) that regularly gets updated to fix bugs & problems and create more fluidity & efficiency, we can do the same to all eukaryotic & prokaryotic life using gene editing & synthetic biology. So yes, enhanced motor functions, cognitive ability, flawless immunology, etc. will be achievable soon. I suspect there will also soon be a revolution in “paranormal” traits that we can also scientifically express through gene exploration too, such as psychic ability, levitation, super strength, turning off pain receptors, astral projection, bi-location, manifestation, etc.. These things indeed exist in some capacity within eukaryotic life already so the ambition should be to discover how such things are being expressed genetically - then we can have fun
The truly amazing feat here is that you keep managing to get Dr. Church on this show, despite your refusal to inform yourself appropriately about his work and the field. For the sake of us [viewers] please bring on a new host or work on your preparation. This is nearly un-listenable.
