I think a video about transition states , delta G , delta H , and intermediates would provide valuable prerequisite knowledge about Sn2. Thank you for your high quality videos victor.
If by NASH you mean NaHS (sodium hydrogen sulfide), the it's quite straightforward backside attack giving you (R)-2-pentanethiol. I'm not familiar with what else NASH might be. I tried to look it up, but there are quite a few different results, so if my initial assumption is incorrect, maybe you can clarify what you mean here by NASH 🤷♂️
It always happens regardless of atom being chiral or not. If atom is not chiral, however, there's no *visible* inversion, in other words, there's nothing for us to show as a meaningful inversion, but it still happens.
I just had this EXACT same confusion , inversion occurs regardless as long as there is a wedge or dash. If there is no wedge or dash in theory inversion still occurs but in practice you can't visually show it since you cant do a wedge --> dash or dash--> wedge. It could be achiral but if it had a wedge or dash you would still invert it.
