6:32 You can tell tell that Kate McKinnon (playing Hillary) is basically saying to the real Hillary, "As a gay woman (Kate), you could have supported gay marriage earlier!" Knowing the real life scenario just makes it even funnier.
The Mike Myers / Mick Jagger impression was hilarious because Mike Myers was impersonating Mick Jagger while Mick was impersonating Keith Richards. Mick was hilarious.