SNRI Antidepressant Mnemonic Review for NCLEX | How SNRIs Work, Nursing Pharmacology 

Review SNRIs (vs SSRIs • SSRI Antidepressants M... ) and how they work in this mnemonic.
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Serotonin-norepinephrine reuptake inhibitors, abbreviated SNRIs, are a class of medications that increase serotonin and norepinephrine levels in the brain. SNRIs are useful in treating depression, anxiety, and chronic pain. Notably, SNRIs have the potential to cause serotonin syndrome, a life-threatening medical emergency. As a reminder, with serotonin syndrome the body is experiencing overactive everything - tachycardia, hypertension, hyperactive reflexes, diarrhea, and so on. This risk for serotonin syndrome is increased if SNRIs are combined with any other serotonin-altering substances, like St. John’s Wort or MAOIs. SNRIs can also cause sexual dysfunction.
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