Synthetic Biology Explained 

great for my right ear

Best intro explanation of synbio I've seen yet!

A great video, well done and explained clear and to the point. Congratulations to the production team.

This is a beautiful presentation in both descriptive clarity and graphic animation.

@Africanlubo The computer doesn't actually create the DNA, they program the machine that makes it. But you can use computers to model specific new proteins and then get the DNA sequence to construct that protein. Or you can use computers to model 3D DNA - something called DNA origami useful for all sorts of things such as molecules for drug delivery. A Google search for DNA origami will turn up heaps Hope this helps, Jason, TechNyou

Amazing video! Excellent job explaining what is synthetic biology!

Very easy for every one to understand. Educational, inspiring and entertaining! Very creative to mix the arts with science to enrich the world

Our children and grandchildren have interesting futures ahead. Let's hope it goes well!

Very simple & ease to understand, great job.

My left ear feels lonely :(

The implications of what this technology can do are both fascinating and frightening.

Kidney + Liver => Kliver :O

There's one channel of audio - the channel I listened to when proofing the video. You listened to the other channel.There wa a 50/50 change of that.

This is truly excellent. Thank you for producing it. I have linked to it on my blog, Running a Hospital. Paul Levy

This technology is just coming online, genetic engineering was just coming online in the 70's, some drugs from that work came out in the 70s and 80s, but the area really fired up in the 90s with patents, drugs and foods. That should give you an idea of the timeline we're talking. Although, computing power (which is a big factor in all of this) is a lot faster now than is was then, so we could be talking this decade, maybe next.

A very Nice Explanation of Synthetic Biology and Programmble Matter startup...

Sorry, what translation are you talking about?

omg GLOWING TREEHOUSE? I'm sold. As if I needed more reason to take biotech in university. =)

Hello! Can I translite your videos? I need your permission to do it. Thanks

This is just about the coolest damn thing I've ever seen.

Sorry, right now the best we can do in Bio-Mechanical right is probably hip replacements. Does that help? It doesn't help, does it....

every advance has many trade offs i agree. it will be interesting to see how this tech will be used in the future and who will be able to use it.

This is as fascinating as scary at the same time. Scared of the easiness by which this is accessible to anyone, and fear of potentially creating a bacteria that becomes unstoppable..

Needs more George Church... but great video overall and very nicely put put together.

Very intriguing. Nice video. Narrator sounds like Christian Bale as an Aussie...

Thanks a lot ...the illustrations are really helpful

They'll be ready next Tuesday, maybe.

One way it could be done perhaps (biologically) would be for the replicator to have a reservoir of specialised quickly-programmable "universal maker" bacteria which can each be programmed to construct and join a small segment of whatever object you wish to construct, and then die. So you'd start with a blob of bacteria, and it would gradually die off to reveal your object. This is the quickest (pie-in-the-sky) way to do it biologically that i can think of.

They are, in fact, already working on this.

This could also lead to some crazy ways to control humans behaviors. If one would create a synthetic parasite it could modify cells and therefore transform a person to the liking of the one who ingineered the parasite.

This I know. By bio-mechanical, I meant a fusion of biological and mechanical on the cellular level.

Incredibly well explained video. Loved it

Ultimately it is a enzyme from a termophilic bacteria(or archaea) that 'makes' the dna, its all coordonated by the computer and all the repetitive tasks are no longer done by hand by someone flipping switches but by robots controlled by a computer.

My right ear enjoyed this video a lot

FANTASTIC

Very good video to explain the subject.

This was before the discovery of CRISPR/ Cas-9!

Can be generated a "carbon capturerer"?

Compared to previous technologies, this gives us the ability to construct self-replicating things, which could require new safety procedures. The risk that we by accident build a doomsday machine is only likely in the movies.

the thing is, there won't be any difference between the two in the future, because biology is just advanced nanotechnology.

Sound all in right channel to anyone else? Seems to be the vid. Make it mono?

Thanks Adrian!

Greed is good. Greed works. Seriously though, it's great that people try to develop new technologies to solve problems for humans. If they get rich in the process, it's just because they are producing useful services. Unintended consequences can always happen, but it's not the kind of thing you can let yourself be paralyzed by with the huge potential biotechnology has to assist humanity.

As long as it's not owned by a few mega multi-national corporations.

Fascinating Stuff

Excellent video!

Simple and understandable.

Excellent video, thanks!

Very interesting. I learned so much. Thanks!!

Where can you by one of these DNA sequences, I have a debate coming up and that would be a great prop

if it were possible, evolution would have already produced such an animal. This is kindof what most bacteria already is, and yet here we are.

Soooooo.......ARE THERE GOING TO BE BIO-MECHANICAL CREATURES IN THE FUTURE?

5:19 You're Breathtaking!

I don't see a major and minor groove on that double helix >:| Also, it's not just sugar, you need a phosphorous source and nitrogen heterocycles from any garden variety garden! And nitpicking is my hobby. Great video!

Superb video.

great video really explains the concept well. but how do the computers create the DNA?

gee what could go wrong?

Nothing good will come out of this. Humans, you are not divine beings.

amazing... thank you

Get ready to join the God clique .

Super helpful, thank you 🙏🏾

Great Science Fair idea

40cents per base pair is pretty much considering how many base pairs human genome has

best explaination

... you'd have to give reasonable and effective parameters for this... and it'd have to be made of a highly sturdy and durable substance. (Such substances aren't good for making joints out of. It's best to wear solid armour.) ^_^

great vid, thanks!

Genetic process not "genetic manipulation": that would infer an outside force "changing" the genetic process by altering DNA. Like what is inferred in The book of Jasher 4:18 "After the fallen angels went into the daughters of men, [then] the sons of men taught the mixture of animals of one species with the other in order to provoke the Lord".

The visual transcription of what the scientists are saying must have been done by a machine or a non-native English speaker, because while usually phonetically correct, it is howlingly bad throughout.

brilliant, reminds me of Hungry Beast in fact, I miss that show :(

What about the idea of an invincible immune system that includes a synthetic organism that reacts and creates new custom organism to specifically combat the new invader? Would that be possible?

Satan can’t create, only intimidate

can i get research papaer used in ppt

Amazing

sure, but that's still going by nature rules,i'm talking about what happens when we at some point become so good at it that we begin making different kinds of people with different kinds of talents, then we at some point will end up with a class system for beings, and it's just downhill from there. well, it's not actually that big a problem, it's more a problem if we accidentally destroy our self with this.

No, at least no in the foreseeable future. You might be able to get it to out compete and provide immunity against one or a couple related organisms now (which would be tremendous), but now what you described in the near future. Still everything is possible in science so someday that or something similar could potential be possible.

Traditional notions of cyborgs might be a bit outdated; awkward, bulky metallic components (even inert ones) aren't exactly ideal matchups with your biology.

fix your computer the audio is fine for me.

How about neurochemical engineering and hence memory engineering, if there's a time to manipulate the brain cells and their network....that moment could be so called the end of developing engineered human. Actually, I reckon genetic engineering is a matter of probability which means there we can see solution at least, but when it comes to brain networking part, god, extraterritorial yet. I want to born at the age when there's no language barrier as brain could be programmed like the genes.

Nice niceee eyval👌👌

Where can I design the gene blocks?

pls pls can someone tell me a Website of all animal DNA and were can i order my dna

This is so cool!!!!!!!!!!!!!!!!!!

''This leads us to the one logical conclusion... We are the gods now.''

Very true. We've got a tendency to bring about unintended consequences in nearly everything we do... That said, am I the only one who's dreaming of tree-ships?

I agree. All do for the most part, people are being rigorously regulated by their government and or religions.

Terrible typos

Normaly the organisations who finance these kind of projects are the wrong hands.

The dna cells has to come from something that once had life or has

good

umm is the star trek maker thing possible?

PM these guys, they may be able to help you find a suitable program facebook.com (slash) biobricks

I cried watching this..it's a beautiful concept!! XDDD N glowing trees got me,LMAO!

007 James Bond movie stuff. Nano meet DNA we gonna mess you up goood !

humanity is over

we already are manipulating with the human body. Surely we are less muscular then our ancestors who 10 000 years ago only stumbled on agriculture. We have changed the way we live and thus manipulated our own bodies and minds, genetically as well as environemntaly.

oh a Replicator? eeeeeeehhhhhhhh maybe. Pretty complex. Replicators make exact atom-for-atom copies of things. IMHO biology isn't really suited to making atom-for-atom copies of anything more complex than a DNA molecule. The big problem is howto store the atom-by-atom data. Since you'd be using atoms to store the data (you'd likely use DNA even), the resulting size of the blueprints would be much bigger than the actual object! But if you just wanted a non-exact version, yeah why not.

Así es

Sooo, how do i get that job again?

Sharks with lasers. Ready, go!

Make trees glow, like in avatar! that would be so great.