Tamoxifen & Aromatase Inhibitors: Let's talk about the side effects of breast cancer treatment

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Dr. Claire Macaulay, a breast speciality oncologist from Glasgow is hear to answer all your questions.
Many women say that being on a long-term anti-hormone treatment such as tamoxifen and aromatase inhibitors is much harder than chemotherapy, radiotherapy, and surgery altogether. So just how can we mitigate these side effects?
For this special episode, we’re also joined by a group of our community so they can ask their questions live on show!
Both tamoxifen and aromatase inhibitors (AIs) are hormonal therapies used in the treatment of oestrogen-positive (ER-positive) breast cancers to stop tumour growth and recurrence and to treat cancer that has come back after initial treatment or that has spread to other parts of the body.
These treatments come with the benefits of reducing the risks of cancer recurrence and they also come with a host of unwanted side effects. Sometimes, these can very much reduce a woman's quality of life.
Dr. Claire Macaulay recognises the challenges these treatments come with and talks us through our options.
Dr. Macaulay is also a certified sex coach supporting people in the menopause to have improved sex lives. You can find her here www.pleasurepo...
About Dani:
The Menopause and Cancer Podcast is hosted by Dani Binnington, menopause guide, patients advocate for people in menopause after a cancer diagnosis, and founder of the online platform Healthy Whole Me.
There is lots of information out there about the menopause but hardly any if you have had a cancer diagnosis as well. Many people say to me they have no idea what their options are, who to ask for help, and that they feel really isolated in their experiences.
I started this podcast because there was nothing out there when I was thrown into surgical menopause at the age of 39, which followed on from my cancer diagnosis aged 33.
Through the episodes, I want to create more awareness, share information from our fabulous guest experts, doctors and other specialists in the cancer and menopause field.
And of course, I will share stories from the people in our community.
So that together we can work towards a better menopause experience. For all of us.
More educated, better informed and less alone.
Connect with Dani:
Instagram @healthywholeme
Facebook: @healthywholeme
Website: menopauseandcancer.org
Join Dani’s private Facebook group: / menopauseandcancerchathub
For oodles of inspiration, healthy recipes, yoga classes, and all round positivity, go to her website: www.healthywho...

Опубликовано:

26 сен 2024

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Комментарии : 86

@ridgestudio 6 месяцев назад

I’ve been taking Letorzole for the last year. I have a number of these side effects. When I’ve asked my oncologist what the stats look like for my situation, I was never given any, just told I should take it. This is the most valuable information I have seen to date. Every woman with breast cancer should be watching this video. All the information given is exactly what I should have been told when I started this journey. Thank you so much Dani and Dr. Macaulay. I am now able to make an informed decision that works for me.

@lyngaspar8545 5 месяцев назад

Same here. Thank u much.

@kelleywatt4167 3 месяца назад

Get off of everything cancer related and don’t look behind you

@jeanmetcalfe786 5 месяцев назад

Great talk after one pill i thought i was dying and i have never taken another..i actually could not see and hallucinated for two hours..God help us women

@agnessymon8869 6 месяцев назад

My oncologist disregards all my concerns. It's like take this and shut up. All he tells me is to stay off the internet. Yet I've learned more on the Internet than I have from any of my doctors.

@kathysteiner9468 5 месяцев назад

Me too

@L-ash777 5 месяцев назад

Same, she can't be bothered, I bet if I had someone to take with me her attitude would be much different

@jeanmetcalfe786 5 месяцев назад

But there are serious side effects with eyesight and terrible headaches also extreme osteoporosis

@susiepingleton3614 3 месяца назад

I bet your oncologist did not tell you that he makes a percentage of profit off of chemotherapy. I was a hospice nurse for 17 years and I watch them lie to their patients up until the week they died. I want to ask my doctor why all of my cancer patients over the years we’re always ball headed? Was it because they were talked into a last ditch effort to use chemo? Of course!! Huge profits! I learned it all!

@L-ash777 3 месяца назад

@@susiepingleton3614of course they do, follow the money. A patient cured is a customer lost

@Elenitsa21 Месяц назад

Dear Dani I am so happy to have discovered your podcast this week. I have been on tamoxifen for two years and have been switched to Letrozole as of a few days ago. I am terrified of the side effects. Your calm demeanor paired with your knowledgeable guests helps me calm my nerves. I have a hard time accepting that I need to take meds that harm the body in so many ways in order to prevent a recurrence. I’m only 51 and would hate to start feeling aches and pains that a much older woman might have. Frightening to say the least.

@KS-yp1jl 3 месяца назад

In light of my specific case, which was a non-aggressive, early-stage cancer, I chose to take just 10 mg of Tamoxifen to avoid potential damage to my uterus, ovaries, and liver, as well as the possibility of other dangerous issues, such as blood clots. While I wasn't overly concerned about side effects, which I had heard were manageable with a proper diet, exercise, and lifestyle, my primary concern was the potential harm it could cause my body. Now, one year in, I can say that despite the pill putting me into abrupt menopause, I have experienced only mild side effects, including hot flushes and night sweats, which are manageable. I follow a low-carb, high-protein, sugar-free, clean diet, and exercise 3 to 4 days a week, incorporating both strength exercises with weights and cardiovascular activities such as yoga, running, hiking, sprints, swimming, and so on. These lifestyle changes have helped me maintain consistent energy levels, minor menopausal symptoms, and a positive mood. I hope this will be the case in the future as well!

@KS-yp1jl 3 месяца назад

Oh, and no alcohol but I wasn't drinking any alcohol even before my diagnosis.

@LaurenaLaw-mr9yg 8 месяцев назад

So helpful for me as a GP with a focus on menopause to listen to a breast oncologist discuss how assessment and treatment are individualised! Thank you for your time in creating such a great resource!

@nancyferrari6743 4 месяца назад

Excellent information. I am grateful my oncologist explained my ER+ issue to me and I am taking my Aromatase inhibitor. It’s no picnic but I take it one day at a time.

@susiepingleton3614 3 месяца назад

I did 4.5 years of misery and now off.

@raelynwhitney939 5 месяцев назад

She said there was another way to see the chart to show not only those who are surviving after 10 years but you could also see how many had ruccurance out of the 100

@kathysteiner9468 5 месяцев назад

Anastrozole nearly killed me with joint and muscle pain

@tarynsanmartino8930 6 месяцев назад

Dani, Thank you so much for finding this wonderful oncologist, your questions, and Dr. invaluable information. Best wishes and prayers to all.

@jackyorrick5512 6 месяцев назад

So informative! Thank you for affirming my decision to NOT do conventional treatment. Holistic is the only way for me.

@mandysho 6 месяцев назад

Brilliant, useful and informative! Thank you sooooo very much for this podcast. It answered my many questions about available treatments and the side effects and how to deal with the side effects. Thank you to your audience too for asking brilliant questions and sharing their experiences and thoughts too. Sending you love and gratitude, and I will be looking forward to see Dr. Macaulay again in your podcast again.

@NancyHomer 3 месяца назад

Re brain fog, I was 40 when I hit early menopause. I had severe BF for 7 years, however going keto and giving up sugar, including fruits, totally changed my life. I only mention it in the hope my experience will help someone else xx

@shirleymilton5178 3 месяца назад

Very interesting to hear that Tamoxifen is mostly prescribed for post menopausal patients.I was diagnosed with breast cancer when I was 52 just 2 years after the start of my menopause. This was in 1994. First I had a double lumpectomy but as the cancer was moving quickly about a month later I had a mastectomy. I was prescribed Tamoxifen first for 2years then it was decided it was reasonably save for 5. However with my doctors agreement I took Tamoxifen for 12 years. I am pleased that I had few side effects though I have been diagnosed with eosteopena which could be linked. However I feel very blessed that I had an excellent woman surgeon and also woman oncologist who was also excellent. I feel very blessed that I was able to see my children marry and know my lovely grandchildren. I thank the cancer team that I had and wish I could do it in person.

@fionaodonoghue9906 9 месяцев назад

That was brilliant so clearly explained thanks

@LB-zc1hj 6 месяцев назад

I have had surgery and whole breast radiotherapy I have ER positive Her2 negative stage 1 Grade 2 diagnosed at 68years old after a routine mammogram. I am fit and normal weight, I walk 30 mins every day. My predict score comes out as 2% benefit this means at 10 years there will be 15 deaths from other things and 7 deaths from Breast cancer they say MAY be reduced by 2 women staying alive ( 5 breast cancer deaths) if I take 5 years treatment. For me at my age and I because I am so allergic so many medicines I don’t think it’s worth it. Also what benefit does whole breast radiotherapy give please? Thank a very informative session which will help me make my decision next week with the GP.

@carolineobrien3770 5 месяцев назад

Look up Dr Thomas Seyfried. X

@campbeja001 5 месяцев назад

Whole breast radiotherapy prevents reoccurrence in ER+ invasive breast cancer (30 pct reoccurrence without radiation vs around 6 pct with radiation). There is an alternative radiotherapy. Hypofractional radiotherapy is a shorter duration higher intensity radiotherapy that has half the intensity of the side effects. This is something you seemed ideal to benefit from so I don't know why it wasn't suggested to you.

@LB-zc1hj 5 месяцев назад

@@campbeja001 I had 5 sessions intensity 26 fractions. The only option offered to me. I can’t understand why radiotherapy treatment if it helps so much is not included in NHS predict scoring?

@JoanneNorris-j9q 10 месяцев назад

Thankyou for all this info and support what would we do without you.....x

@smcawwca 10 месяцев назад

So informative!! Thanks to you both.

@annemarieriley1138 5 месяцев назад

Really enjoyed listening to Clare. Thank you

@montsefernandez346 10 месяцев назад

Really informative - thank you!

@susiepingleton3614 5 месяцев назад

I have suffered with all side effects. I have taken anastrozole for 4.5 years. I am done. Ha! I am stage lll. Oh I will not live another day miserable! Affecting my urethra now! I stink. My breath stinks. I am an RN . I was a hospice nurse for 17 years and watched all oncologists lie to women to get that profit!! 26% improved chance ? Not worth it! One oncologist is on RU-vid apologizing as she was shocked at her symptoms! She had to take it. 50% of us stop the anastrozole. I am done.

@carolineobrien3770 5 месяцев назад

Look up Dr Thomas Seyfried

@deniseragona2383 4 месяца назад

So sorry you're going through these side effects. I'm a ten year breast cancer survivor. I was on Tamoxifen for 4.5 years. Side effects are terrible. Unless you live it, these doctors will never understand it. For me, it's all about quality of life.

@Veronica-kp1xj 3 месяца назад

Thank you you helped me to decide 😢Iv been so miserable trying to decide what to do.im not going to take it.

@ElizabethVenus-cg3hp 9 месяцев назад

Had the pleasure of joining this workshop. Great to be able to share it far and wide . Thank you Dani X

@kathryn2334 Месяц назад

This is such a kind, informative, helpful video. Thank you!!! I am so greatful to have found you. New subscriber.

@sarahcooper6507 3 месяца назад

Who is this excellent oncologist

@deniseragona2383 4 месяца назад

Thank you! Powerful information!

@CS-ow4gl 7 месяцев назад

I’m Listening to podcast number 82. I can’t find the video matching . My question is you mention a drug used for high blood pressure that helps with high blood pressure. Clonadine ? Thank you !!!

@vilmavelazquez1979 6 месяцев назад

Good video. Why the predict tool does not include radiation?

@karlinebohne789 3 месяца назад

It’s out now !

@L-ash777 3 месяца назад

@@karlinebohne789 I've looked for the new version tool and can't see it, do you have a link thank you

@jennywinks7979 3 месяца назад

My oncologist told me that PREDICT was “old science “ and the ONCOTYPE SCORE now makes PREDICT scores obsolete. Can anyone speak to this? Thank you for any insight.

@karlinebohne789 3 месяца назад

Oncotype provides a score that can give you insight as to if chemo will help or not ( for me my score was 11 and they told me under 20 is good over 20 chemo was recommended.). Also stated it would provide an indicator of reoccurrence which I haven’t been told anything about that thank you for the reminder I’m going to ask for my report

@DeeElle2 3 месяца назад

My friend took tamoxifen and was very sorry she did. She got cancer and then died from the chemo. Her son posted her agony on facebook of all places, and I can’t I see her pain as she died. She was a previous smoker, and I’ve since learned about oxalates and would definitely incorporate a low/no oxalate diet to reduce inflammation. Sally K. Norton wrote a book about it. Doctors only think it accumulates as kidney stones, but it’s also involved with breast, colon and thyroid cancers. Do your homework ladies.

@L-ash777 6 месяцев назад

If you say lose weight then how come thin people get BC. You are talking about DVT, I got a PE with no symptoms, no DVT, just lucky I had a whine about aches and pains generally.

@lisanapolitano1233 4 месяца назад

This is a remarkable video. I’ve just been diagnosed with bc and am about to endure a bilateral mastectomy. HOWEVER in the second example please CORRECT to show that 8 people survive with five years of aromatase treatment - NOT 13. You can add a subtitle for correction. And thank you from the bottom of my heart for this information. 🙏❤️

@turtley8883 5 месяцев назад

I'm on the predict website and I filled out the info. There are no fields for BRCA genes. I have the brca mutation. Does it not factor into the results?

@KS-yp1jl 3 месяца назад

I think it does.

@devendavid6535 6 месяцев назад

What is. stradexa I'm on this treatment

@paulah317 3 месяца назад

Unfortunately it's not a partnership with the oncology "team" in many, many cases.

@jackiekabadila4015 5 месяцев назад

Can I take magnesium while I am on tamoxifen?

@nancyferrari6743 4 месяца назад

Random question. IF a woman stops taking her AI pills, how soon does cancer come back?

@KS-yp1jl 3 месяца назад

No one can answer such a question. It's impossible to know.

@roberttate-q3e 3 месяца назад

Those clinics have a quota they strive for They will get their$$$$

@annemarieriley1138 5 месяцев назад

I'm about to start tamoxifen but am very scared of side effects. I am post menopausal.

@susiepingleton3614 5 месяцев назад

You should be taking anastrozole not tamoxifen! Good grief!!

@kathysteiner9468 5 месяцев назад

Who are you. I took Anastrozole and I can't believe they have women taking this. It about killed me. Going to truTamoxifen. If I have horrible side effects, I'll say screw it

@kathysteiner9468 5 месяцев назад

No lay person has a right to tell you what to take. I took Anastrozole and it nearly killed me. Will start on Tamoxifen on Monday when my docs office is open in case I have allergic reaction

@susiepingleton3614 5 месяцев назад

@@kathysteiner9468 I am an RN. I took Anastrozole for 4.5 years and quit last week due to inability to live with these side effects.. tamoxifen is for those still menustrating. So many in stage l jump on board!! I have studied the percentages, the predict charts etc. I am done. I have stage lll with 19 bad lymph nodes and I will quit anastrozole to have maybe a year of extra life to years of feeling better? No thanks! Next five years will tell my story. I was a hospice nurse 16 years and could write a book on all the lying oncologists!$$$$$$$$

@campbeja001 5 месяцев назад

Anastrazole is contraindicated in patients having osteoporosis. That is why Tamoxifen is usually preferred on that scenario. Aromatase inhibitors will accelerate bone loss!!

@devendavid6535 6 месяцев назад

I'm started taking Stradexa. Today l want to know what this does to my body its Mre David Vasie

@laureeniannucci4878 3 месяца назад

Why aren’t there side effects for treatment longer, thicker hair, stronger fingernails, weight loss, etc??? Asking for a friend…. 😀

@lisamurphy6203 6 месяцев назад

I've had a bad response to Anastrozle. It raised my BP to 215 in 8 weeks. I hadn't a problem before that ,age 66 .I was then prescribed 2 BP meds, had to see a cardiologist as it wasn't reducing. He said I can uncontrollable BP, most likely from the Anastrozle. I've reduced taking the Anastrozle to every second day and BP has reduced. A oncology nurse said to me it would probably return to normal if I stopped taking Anastrozle. Will I get some benefits from taking it every second day, or just give it up all together. I had an oncotype DX score of 6. I don't want to risk a stroke with the uncomfortable BP.. Lisa

@kathysteiner9468 5 месяцев назад

I did that, it has a long half life.

@jamiebond8481 5 месяцев назад

Here we go … brain fog - we are aging beings. She just dismissed a valid concern and a side effect. 👎

@meredithholmes1521 5 месяцев назад

I think she meant we might be experiencing brain fog as older women 50+ due to the high stress and mass information we are giving in the working environment. This is true for me, I think

@IreneRattray 3 месяца назад

👆👍

@jeanmetcalfe786 5 месяцев назад

Is estrogen really the enemy

@christinakuczora4862 3 месяца назад

Every cell and organ system in your body uses estrogen including your brain. Personally, I don’t want to cut off the estrogen to my brain - risking dementia.

@mypaleogut 3 месяца назад

I’ve just been diagnosed this week with ER PR HERnegative 12mm grade 1. I’m 46. Just used the predict and it seems to show 15 year survival rates are same with or without radiotherapy 96%. My surgeon says he’ll cut it out next week and do radiotherapy. Should I ask if I need this? Any ideas whether to have or not? I’m carnivore, zero sugar and plan staying in ketosis rest of my life. I’ve heard cancer can’t live in ketosis body anyway?