The Cure Chronicles: HIV with Janeli Alejandra

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Janeli Saucedo-Castrejana is a TikToker and mother of three. Janeli was diagnosed with HIV in 2010. She fell in love and did not let the fact that her soon-to-be husband was living with HIV stop her from marrying him. They were cautious throughout their relationship and marriage, but shortly after their marriage, Janeli tested positive for HIV. It took her some time to get to where she is now, but she decided to start sharing her story on TikTok to give others helpful information and hope for their futures. Today, Janeli is an HIV advocate both on social media and in her real life.
About The Cure Chronicles:
There are more than 38 million people in the world currently living with HIV/AIDS. At American Gene Technologies® (AGT™), we believe there is hope for a cure. But it will take everyone working together to make it a reality and permanently end the suffering of millions of people living with HIV today.
AGT is testing a single-infusion cell therapy (AGT103-T) to hopefully cure people living with HIV. Meanwhile, we want to spotlight some of the many people in the HIV community who strive to keep hope alive and tip the odds toward success.
The Cure Chronicles video series features thoughtful conversations with people living with HIV, advocates, medical experts, policymakers, and others working hard toward the shared goal of ending the devastating HIV epidemic.
If you like this video, please subscribe to our channel: www.youtube.co....
Also, please leave us a comment to let us know how you liked it as well as any additional subjects you’d like us to cover.
About American Gene Technologies:
AGT is a clinical-stage, gene and cell therapy company in Rockville, Maryland with a proprietary gene-delivery platform for rapid drug development of infectious diseases, cancers, and inherited disorders. AGT's mission is to transform people's lives through genetic medicines that rid the body of disease.
Visit our website: www.americange...
Subscribe to our newsletter: bit.ly/3ughPNR
Follow AGT on social media!
Twitter:
Jeff - @jeffreygalvin - / jeffreygalvin
AGT™ - @americangene - / americangene
LinkedIn:
Jeff - / jeff-galvin
AGT™ - / amer. .
Facebook: / amerigene
Instagram: / americangenetechnologies

Опубликовано:

21 сен 2024

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Комментарии : 54

@AnthonyJohnson-hl1ru 2 года назад

We need a cure!

@franciascafranciasca4549 2 года назад

❤️❤️❤️❤️❤️

@jaybrainz6948 2 года назад

@@Lee-1 no cure yet. hopefully sometime in the future.

@jaybrainz6948 2 года назад

@@Lee-1 there are already some types of cancers that are already curable though. Such as Melanoma, Prostate, ect.

@gwgwhywy4934 2 года назад

@@Lee-1 I feel depressed and frustrated, science feels like a joke, it's been 40 years that hiv has ravaged people but until now science is still powerless. I'll probably kill myself before the disease progresses, really disappointed

@JudeBoi1313 Год назад

We’re close

@Kevin-1969 Год назад

Imagine if there was a cure for this

@jaydupree422 Год назад

To all out there, stay focus on your health, meaning eating exercising right, try not to stress your self out, let us all put good energy out there in the universe, and claim it, agt will get this cure, hopefully sooner than later, or agt working with another company for this hiv cure, these scientists are on the ball, mean while stay 💪 strong

@arthurjacobfuentes7671 Год назад

I pray that she doesn't get cancer

@matharasantewaa586 2 года назад

Agt we are patiently waiting for the results, May we received a good result out of it ,. Amen

@gwgwhywy4934 2 года назад

I always hope for good news to come. but hope is only hope if we continue to study science slowly and lazily like this

@matharasantewaa586 2 года назад

@@gwgwhywy4934 it seems like they don't know implications about the deases,if they really know and have experience it before, they would have speed up the research

@AmericanGeneTechnologies 2 года назад

The trials are not something that can be sped up. We are working as hard as we can to find a cure for this disease but things like this take time as we have to follow government regulations.

@matharasantewaa586 2 года назад

@@AmericanGeneTechnologies government regulations ! Like what? Whilest we are surffereng, when?

@gwgwhywy4934 2 года назад

@@AmericanGeneTechnologies the government is really bad to introduce experimental regulations on hiv that i think is not appropriate, because they just sit at the desk making regulations without knowing that their regulations are making it harder for people researchers and hiv patients.

@sJ-ls8pw 4 месяца назад

Did everyone catch that???? The protocol for the public for PEP (Post Exposure Prophylactic) is a 28 day course but it is different in a medical setting in time to get the drugs and dosage taken. Also 10% chance of infection during an exposure incident.

@gossipwestcoast9745 Год назад

How did he get it

@gufrankhan1081 2 года назад

Sir from India we are very helpless,,,

@icedteagames Год назад

I liked this story, thanks for sharing

@AmericanGeneTechnologies Год назад

Glad you enjoyed it!

@gwgwhywy4934 2 года назад

do we have any cure sir jeff

@MiraRamirez-fv3uh Год назад

So amazing how love is so powerful.

@xXSeak Год назад

So she turned HIV positive even on PEP for 28 days? She didn't mention that she actually took it for 28 days. Anyone knows that crucial information about her case?

@Mr.Majestic77 Год назад

Her current husband who was previously HIV+ did not take his medication on a routine basis. It is still U=U (Undetectable =Untransmittal), but individuals still need to adhere to taking their medications on a routine basis.

@sJ-ls8pw 4 месяца назад

No, she didn't know about PEP. She didn't take anything.

@nguyenvanhung529 2 года назад

mong các nhà khoa học các nước nghiên cứu trị khỏi hẳn hiv nhanh nhất có thể ạ

@TanTran-vy1ow Год назад

kB Nói chuyện đc ko bạn

@saintlitt7075 9 месяцев назад

Eat healthy!!! Love, don’t stress,

@varun33362 2 года назад

When this medicine/vaccine come in market.

@dixonjoe4561 Год назад

@@SagarKumar-vj8hp hi bro

@dixonjoe4561 Год назад

@@SagarKumar-vj8hp u from bro? R u hiv positive?

@mpkumar6120 2 года назад

Ye Puri trah cure ho gya hai ki avi trial ho raha h please zalur btana please 🙏

@aussiejace8572 2 года назад

Any updates on the human trials or has that all fallen apart now??

@AmericanGeneTechnologies 2 года назад

The independent Institutional Review Board overseeing the clinical trial approved the next step of the clinical trial: analytic treatment interruption. American Gene Technologies has begun withdrawing participants from their antiretroviral drugs, which will ultimately reveal whether they are cured of HIV, meaning they no longer need daily medication, and can’t develop AIDS or become re-infected with HIV. American Gene Technologies expects to reveal the results of the ATI by the end of this year (2022).

@aussiejace8572 2 года назад

@@AmericanGeneTechnologies Thanks for the reply. Keep up the good work everyone is thinking of you guys and please keep us inform if not weekly but fortnightly on the study.

@matharasantewaa586 2 года назад

What do we have to say? we have nothing to say all that we can say is hmm we are still waiting for good news to reveal

@sandra2337 Год назад

@@matharasantewaa586....sorry to ask asantewaa re u hiv+

@Mr.Majestic77 Год назад

@@AmericanGeneTechnologies What is the possibility of American Gene Technologies and Excision BioTherapeutics (developers of EBT-101) combining their research into a possible AGT103-T + EBT-101 combined therapy, in the possibility of having a "sterilizing" cure of HIV? As of now AGT103-T & EBT-101 are both being independently demonstrated for their safety and effectiveness before possibility combing both therapies, which are completely different approaches as AGT103-T grants HIV resistance to the T cells that are responsible for hunting HIV, allowing them do their job and fight HIV, like you would for any other virus. This includes continuously fighting the viral reservoir. EBT-101, on the other hand, is a temporary pulse of CRISPR-associated gene expression that aims to cut out all HIV from the human genome, but since the CRISPR-associated genes cannot be continuously expressed, they need to cut of 100% of HIV proviruses during their expression window, otherwise HIV can just replicate and return. American Gene Technologies will need to see updated data from both therapies to know how well both of them work and whether or not an AGT103-T+EBT-101 combination therapy would be warranted. Both AGT103-T & EBT-101 are both in clinical trials, which usually takes between 2 and 5 years because each time a patient is infused, they are extensively monitored for side effects, efficiency and variations in their response to the therapy. In regards to AGT103-T, in theory AGT103-T could be given a dose preventively, as a vaccine, but it would be significantly harder to make due to the lack of HIV specific TCR enrichment that are seen in PLHIV. Also, T cells which do not encounter their target will naturally reduce in number, so it's possible that AGT103-T would not be permanent in people who do not have HIV. AGT103-T archives the same functional effects as delta 32 variant (CCR5Δ32), which some people are born with and when HIV tries to enter their cells, it can't grip onto the mutated CCR5 produced by these individuals. AGT103-T does deliver miRNA to prevent CCR5 from expressing on the cell surface, which makes cells resistant to HIV entry.