The Discovery of Insulin - The Miracle - Medical History - Extra History - Part 1 

wait how is this post 2 days old?

@@thepoglin8479 it was privated

WASNT NICOLAE PAULESCU WHO DISCOVERD THE INSULIN

Wait you still didn’t finish the takeover of India series

A STORY ABOUT A CANADIAN LETS GOOO

@@scottanno8861 ok antisemite

if anything, I blame insurance not covering enough

It's not just insulin, but other drugs, too.

@@GiordanDiodato nope it’s pharma, and government refusal to advance along with the rest of the developed world with free healthcare.

Right now one vile of insulin costs about $100

Alcohol doesn't necessarily lower blood sugar, it's different for every person. I'm diabetic and my blood sugar may either get really high or really low whenever I get wasted even if I am carefully controlling it. And coffee is probably one of the worst things to give to someone with hyperglicemia: your heart may simply not withstand pumping thicker blood real fast (my heartrate when I have high blood sugar gets high even without coffee).

Booze

I mean what I want on my death bed. Lol

@@user-pj5wf3jm2u I would have thought the opposite for alcohol, since alcohol breaks down in to sugar.

@@Docwilson91 alcohol makes your blood sugar raise first, and then drop dangerously.

Exactly.

I kinda choked up a bit at that part honestly.

Hello. Again.

2 years ago, at 24 years old, being 1.80 m tall weighing ca. 75 kg, I was diagnosed with Diabetes. Docs said basically since I'm not fat or old it's most likely type 1 Diabetes. About 1 week before the diagnosis, I weighed ca. 80 kg. In just one week I dropped 5 kg all the while eating like crazy, especially sugar (which was weird for me, since I wasn't that much of a sweets snacker), getting up every night to drink about 2 litres of water and piss about 6 times. Only at night, imagine the days. Also, I normally sleep through the night "in one sitting". I felt incredibly weak and weirdly hungry, my eyesight was extremely blurry and I was constantly in a daze. Sure, those parents probably had the greatest day of their lives, but those kids must have been through hell and beyond. Finally feeling energized, not having the urge to stuff yourself or drink water like you went through a desert for 3 days straight. Having hope not to die with your 10 years of age. I only felt symptoms for a couple of weeks, they suffered months or even years AND most likely felt responsible for their parents sadness. It's kind of macabre to say, but.. you "may always" have another kid, but these kids would never have another life (I know it's far more complex, hence quotation marks). I know what you wanna say and I'm not challenging you think otherwise, but getting handed back a chance at life as a "healthy human" is far more than just wonderful. Or at least, what I wanna say is, of course one shouldn't forget the parents, but I think those kids were the happiest on the days of their first injections. Then again, you might be a parent, I'm a guy with Diabetes, so no wonder I feel the kids should be the focus and not the parents. In the end, there's nothing wrong with your comment, this text is only a justification as to why I feel in disagreement with it. Guess it's too personal for me lol I'm just grateful I may live on, I can't imagine how utterly thankful those kids must have been. Have a nice day everyone!

Yeah

Someone needs to tell Banting about the drug market today, he'd probably physically manifest as the Doom Slayer

@@notme8232 Nah, we'd suddenly get treated to a real life vigilante, only known as Bantman.

often I feel tempted

these days greed is maximized

sir you have an option tell me or lets say broken bones will be made and you've got a lot of bones

Millions of lives and counting, myself included.

aaaaaaaaaaaaaaaaaaaaaaaaaaaahahahahahahaha you AMERICANS crack me up.

@@DomyTheMad420 hahahahaha, yeah we totaaaaally dont want free healthcare and the ability to get help without being in debt the rest of our live but neither goverment party will give us that. Yeah we want to be in debt, its our fault

@@DomyTheMad420 indeed, laugh at our suffering

Empathy and care made it possible. Capitalism made it inaccessible.

I admire Banting's response to the standard practices of the modern pharmaceutical industry. We could use a few more guys like him.

@@Lazarus1095 it wasn’t only Banting though he had a humongous part in it

@@IcecreamMcGuy I think they’re talking about his anti-greed stance, not his overall contributions to the project.

If you this that's admirable (as you should), then you'd be the most despicable sort of hypocrite if you support the FDA preventing people from getting access to medicine they want.

@@ShankarSivarajan Um, no, that doesn't follow. The FDA prevents drugs that don't work or that have catastrophic side effects from going onto the market. Thalidomide is the classic example. Did you mean the Patent Office?

Open source wasn't a thing back then. Think one of the first thing I would do is to hand him a Apache 3.0 license and a lawyer

maybe we should take notes as to how he convinced collip not to profit off it

Go ham on them like he went on Collip. Probably be proud of Canada for not succumbing to greed and ensuring everyone who needs it can get it for free/cheap.

My man would have gone to big pharma personally and beat someone’s ass.

Type 1, I don't know if I feel anything is simultaneously as evil and prevalent as charging people money for life sustaining medicine.

I think we need Banting to come back and beat up the for profit medical system we currently have

@@millersam07 amen

Insulin is also expensive in other places. In Poland my father's stock of insulin for 8 months costs around 200 dollars. Thankfully Glucometers are free with prescription for strips (I sent one to a friend in US) and strips with prescription cost only about a dollar for 50 (without prescription price is about 10 times). The reason partially is that companies use their own refined methods of mass producing insulin. By that I mean artificial insulin. Of course it should be cheaper, but that is only part of problems your country is facing. Without Universal Healthcare system - every insurance company negotiates for themselves. In Poland government speaks for 38 million people, so they can bring the prices down.

It’s expensive because Canada sold the patent for it to the USA

Private profiting is a two edged sword. In the hands of someone less trustworthy it would make it worse. But someone who asserted themselves as wanting to control it only because they distrusted other organizations but trying genuinely to make it cheaper for people can probably do more for people than the government. It's like the risk of a bad king vs wanting a good king to be powerful making it hard to figure out if monarchy is a better system or not. In the end really neither system is better: individual people will either use the systems in good faith, or they won't. A good person can make do with any system.

Thank you! It's pretty sad that he dosen't really get recognition if at all.

I'm curious if Paulescu the ultra nationalistic antisemitism who administrated the insulin extract rectally instead, had same opinion about the medicine most be cheap and access for everyone have right and afford to buy it?

My take might be kind of hot here, but it sounds like Banting wouldn't have liked anyone who wanted to patent, and maybe he let that straight up prejudice him?

@@donaldduck9884what does any of that have to do with this 🤷 ford was an absolute ahole u still learn abt him and the founding fathers owned slaves

@@mattmathematics3591 Founding father? I'm totally confused what you are talking about so pls explain better what you talking about?

I second this.

My 86 year old grandmother whom I am very close to had to get one. She got CoVid-19 and had no primary symptoms whatsoever. Then almost as soon as she recovered she developed major arrhythmias. She had a profoundly healthy heart for her age before then and no cardiac family history. The doctors said it was most likely the far more pernicious Post-Acute Sequillae. They were able to put it in with pin-hole laprascopy in twilight sedation, but she goes in about once every 30-60 days because of remote monitoring issues now for medication adjustments or defribullation.

Jarvik artificial heart would be cool too

Yeah that would be cool

The end of this comment makes me worry about the test subject involved in the project, but my grandma's had a pacemaker for years sooo...

*Terry Pratchett voted best author ever*

Is she doing better now?

Wealth, fame, power. The world had it all won by one man: the Pirate King, Gold Roger!

Funny is that MOSTE of them generally agreed to forfeit the fortune part, from what was said in the video, the fights seemed to be mostly boiled down to fame and recognition.

I think that when people are desperate, they honestly will let go of these temptations. Everyone is naturally tempted, but most want to overcome it.

@@bungalo50 *Pirate King, Atomsk; not Gold Roger.

@@bungalo50 Actually, it's Gol D. Roger.

From a type 1 diabetic, thank u Canada

​@@zakariaraqiq Romania did it first

Sending good thoughts for your son. 🙏🏻🙏🏻🙏🏻

The discovery of Recombinant Insulin also was huge in making life better for people with diabetes. As stated in the video, the 14 year old had an allergic reaction to the beef insulin. Recombinant Insulin was created by using bacteria to create human insulin by biomedical engineering in the 70s. This greatly reduced the risk of an allergic reaction due to impurities and the foreign elements in boar and cadaver insulin, which were used since its first discovery. Science!

How much is his insulin costing you If your in the us

@@kestrels-in-the-sky Luckily we are in Czech republic so we are not paying anything. Got insulin pump for free, sensors for free, insulin for free, education about it all, glucose meter which also measures ketone levels and all the testing strips for it (just both one set of ketone strips with my own money), all the infusion sets for the insuline pump and also disinfectant and such for the changing of them. And also the emergency syringe for hypoglycemic shock was for free. So glad we live in developed country with universal healthcare as quick sum of all the stuff is around 130 000 CZK so around 6 000 USD.

I'm gonna ruin you moment of 69 likes. Here's a like to you and your son. Give him a hug from me. I may not have diabetes but I at least know that emotional support is very important in trying times. I've had a lot of trying times but rarely got the support I needed. I wish him well. 😁

Ghost of medicine past

+

Let's plunder those islands for corporate profit.

I claim those islets in the name of the Spanish Crown and our Beloved King Ferdinand II of Aragon and our Queen Isabella I of Castile! **plants flag into my own pancreas**

@@espio87 you can have mine :/ they're not functional anyway

Well time to colonize my body britain and France eat your HEART out

Nice man.

Yeah extra history.

I'd watch that

I'd like to see it expanded into an "Extra Science" channel. Interesting things occur in the other branches of science too, and its history thereof. Stuff like the life of Antoine Lavoisier (discovered oxygen, invented medical cross-ventilation, revolutionized tobacco farming, Mrs. Lavoisier translating scientific papers from English to French for him and his papers from French into English for publication, rewarded by being sent to the guillotine during the French Revolution), Erastothenes's technique in ancient Greece for measuring the circumference of the Earth to an error of less than 3% (they knew the world was spherical, and Aristotle could prove it in five different ways), the Stanford Prison Experiment (which had to be called off after less than halfway through due to the madness the people undergoing it were experiencing), and, while this is still ongoing, a rundown of the atomic elements discovered by Yuri Oganessian (who discovered or helped discover twelve elements--bohrium, meitnerium, hassium, darmstadtium, roentgenium, copernicium, nihonium, flerovium, moscovium, livermorium, tennessine, and oganesson, the last of which was named in his honor by his team--the most of any one person, and is still alive and still looking for more). Speaking of chemical elements, polonium has quite the rich history, used for both good and evil. Marie Curie named it to bring awareness of her home country of Poland, and it is extremely radioactive, so much that it was used by Russian spies to discreetly poison KGB defector Alexander Litvinenko...and was radioactive enough that the taxi he rode had to be decommissioned for being too radioactive to use simply because he sat in it for half an hour after ingesting a grain of polonium.

We already have too many extras. Extra SCIFI, Extra Credits and Extra history.

@@history-jovianextra mythology

thx for your username and god bless you

Best of luck managing your condition!

It's not literally cheaper than dirt to produce, but it is fairly cheap to produce. There's a massive markup.

i get it for free in Brazil. Free Healthcare is great

I doubt evryone who don't agree with American pharma looting it's people are communist like the capitalist pharma companies of india and china would like very much of there cheaper product would get access to American markets and break the monopolies.

Damn corpos ruin everything. Curses upon them all.

@@SafavidAfsharid3197 That's the point. People who call those who want America to get better healthcare system "communists" are wrong.

My grandfather is also diabetic

You can buy handheld testers for a few tens of $. You need the test strips and those little snap pin things (don't know the technical term) but those will give you enough information about where your blood sugar is. Places like aliexpress or ebay or even Amazon if you want to buy Bezos more yachts. I'm guessing you are in the US - and Dr's will connive with the companies to reel you in for unnecessary lab tests that can be done on this sort of unit at home. Ex partner had it amongst other people. Test in the morning first thing and at night - if yours tends to go on the low side keep chocolate or something similar available at all times.

Yeah, it's insane and downright evil how much money US pharma companies charge for insulin. Especially if you look up in Canada and see that you can get a bottle up here for under 20 bucks. It does NOT need to be as expensive as it is down south. :(

albeit, a problem that roots in the American medical system... I hope the US will wake up and rework the system but unfortunately, I won't hold my breath.

[Gets Spanish flu flashbacks]

You'd be surprised.

I have type 1