Toadette's First Ever Appearance in a Mario Game (Mario Tennis Color, 2000) 

Toadette debuted in Mario Tennis on the Game Boy Color (2000)
Last Year, Nintendo confirmed that the GBC in fact a part of the Original GB's Family while the Wonderswan and Wonderswan Color are Addons for the Game Boy Series but also there's a 64-Bit Wonderswan Advance that released in 2003 that has similar Graphics to the Original DS which the WSA is a GBA Addon