TWiV 1150: Clinical update with Dr. Daniel Griffin

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In his weekly clinical update, Dr. Griffin dives into West Nile virus in New Jersey, poliovirus vaccination campaign in Gaza and Afghanistan, California dengue virus infections, children dying from flu, mpox vaccination procurement and antiviral usage, flu circulation in US, before reviewing the recent statistics on SARS-CoV-2 infection, finding a new wasterwater dashboard, if the monovalent XBB.1.5 COVID-19 vaccine is effective against circulating SARS-CoV-2 isolates, the need for nasal mucosal IgA in response to SARS-CoV-2 infection, where to find PEMGARDA, does administration of molnupiravir reduce symptoms in the vaccinated, when to use convalescent plasma, how molnupiravir treatment leads to better outcomes 3 and 6 months after treatment, a reminder of how and when to use steroids to treat COVID-19, what do when healthcare workers succumb to SARS-CoV-2 infection, if vaccination against SARS-CoV-2 does protect against long COVID, and if those taking the anti-diabetic drug metformin have higher or lower incidences of long COVID.
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Опубликовано:

21 сен 2024

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Комментарии : 63

@DudeFun-yi7nu День назад

You guys are among the most generous people in the world, it's a pleasure to be here

@tonytyrrell7271 День назад

@@DudeFun-yi7nu I love the use of the word generous. Reminded me of what this really is. I don’t want to take this for granted.

@lyellbrown9766 День назад

I’ve been watching this show for a while now, and the both of you are doing a brilliant job.

@vin5388 День назад

Please don't ever stop doing this - it really matters!

@JillKnapp День назад

Many, many thanks for sharing your knowledge with us! The viewer questions/answers were especially great this week.

@WillNewcomb День назад

Thank you thank you. I always listen closely and try to learn!❤️❤️❤️

@Logotic 22 часа назад

I'm not that personally worried about covid at this point, but I just want to give love & respect to the lady who wants to know how to protect herself from covid while she serves as a poll worker. That actually brought a tear to my eye. If you're reading this, Linda, thank you for your service! 💙

@bid6413 День назад

Thank you both again for all the effort you obviously make to produce these weekly episodes. They are GREAT! Do you have updated information on the relative effectiveness of the Novavax, Moderna and Pfizer boosters? Best Wishes, William Bailey

@marg716 День назад

Thank you for sharing your time, effort and expertise. 🎉

@helengarrett6378 День назад

FYI I'm 83 now. I have had flu vaccines every year in late September or early October every single year as long as it has been offered by my HMO. I have diabetes and asthma, high blood pressure and my age is a factor. This is a sample of one, but I do not get influenza. I go shopping every week at a busy grocery store and go to my local farmer's market that is quite busy Spring through Autumn. My family visits and my caregiver moves from home to home six days a week and has exposed me to covid which I did not get because I am throughly vaccinated for that too. I live in a huge complex of apartments and density for over a mile all around is very high so opportunities for infection are high too. When influenza has raged through our apartment complex I have not been infected. I am an advocate for vaccinations, not only because it works for me, but also because it will work for you. These days I mask at the grocery, but not at the outdoor farmer's market. I wash hands fairly often but not incessantly. I also keep current with all other vaccines. Why can't others be as diligent?

@Hdc2390 День назад

Asymptomatic

@helengarrett6378 21 час назад

No, healthy. Probably not asymptomatic. Cautious and properly protected. My set and only case of Delta (probably) covid almost did me in. My blood oxygen dropped into the upper 80's, especially when I had to use the bathroom or eat. It lasted more than 2 weeks. It was 3cw3eks until I could change my sheets. I think I would know if I was a little "off." That covid infection scared me so badly that I'm very cautious now. I plan boosters for the holidays so I can see my family for special occasions. My kids have had it two or three times each because they socialize much more and will not mask now. But they keep current on boosters and vaccines too. The covid boosterscdon xt keep my kids from getting infections but they keep them out of the hospital in middle age, one having diabetes and the other asthma. They have had paxlovid for the nire recent infections and did well with on need for a second round of it. Use common sense and keep informed from reputable sources like the AMA and TWIV on YT.

@5955yt День назад

But great show, thanks for all you both do!

@Turtledove2009 День назад

Thank you.

@midgehobbs6886 День назад

Great information yet again. Thank you both

@IFSpecialist День назад

Thank you for another informative video.

@chinupduck4849 День назад

Looking really tired and losing weight rapidly. Raspy voice. Hope all well.

@litsci1877 17 часов назад

Hey, thank you guys so much for continuing to provide these updates. In a time so full of selfish people it's so good to see the good worried doctor and his scientist friend trying to shine some light and do something for people.

@alijawad2042 День назад

That's excellent .Thank you very much guys.

@ryanburgoon7354 День назад

My husband and I got the first 3 doses in 2021. We did not get covid until Jan of 24. Our primary care gave us a zpak on day 2 of our illness. We both felt fine after 4 days.

@Rene-uz3eb День назад

Health is a quadrillion dollar industry

@jreyn2 День назад

I don’t know if I have this just right, but it’s close: Perturbations in motion of Uranus (FACT) didn’t fit the theories developed at the time (Newton and, I think, Kepler). The laws (THEORIES) certainly weren’t thrown away. The fact was shelved until an explanation for it could be found. Eventually, the fact was integrated into the theories with the discovery of Neptune. So, let’s not be too simplistic. Naturalistic inquiry advances with good logic, open minds, and willingness to be puzzled by the apparently simple or obvious. 😍

@sophiasage1379 20 минут назад

I think it’s healthy Dr. G is losing weight. Hopefully he’s not sick just doing it because he’s a doctor! It’s healthier.

@ryanburgoon7354 День назад

I should reference my last comment. First 3 shots at age 63, first covid at age 66

@beckyconstantinides2546 День назад

Please give us the current symptoms for Covid 19. I have had a cold that stays in my nasal passages for almost four weeks. Sometimes have a fever. What does Covid19 present as symptoms and am I still able to transmit the viral infection I have.? Thank you .

@christopherrobinson7541 День назад

Unlikely to be COVID-19. Perhaps you should get a LFT.

@beckyconstantinides2546 День назад

@@christopherrobinson7541 what is LFT?

@Hdc2390 День назад

It's all COVID related. COVID is so rampant and constantly mutating we'll probably never have a mild common cold like we did before 2019

@sophiasage1379 19 минут назад

Did you test??

@beckyconstantinides2546 12 минут назад

@@sophiasage1379 my daughter with the same symptoms and her 10 year old were tested at home and were negative. I babysat for the 10 year old and promptly got his symptoms. They are both still having lingering symptoms for four weeks now.

@WauwieF День назад

What happened to the TWiV audio quality lately? Why are episodes so super quiet? This is, after all, an audio format (at least that's how it started and how I still consume it), so please go back to the former good quality we had been used to. Much appreciated.

@traianliviudanciu8665 День назад

Maybe intradermic way of vaccination increase more IgA secretory antibody ?

@traianliviudanciu8665 День назад

Maybe If ,,cold agglutinine,, occur ,warmed oxigen (warming water in barbotor)can prevent erytocite aggregation at lung capillary level ?

@5955yt День назад

Like all the facts that were censored away and kept from people during the pandemic. Thanks to freedom of information the truths are coming out slowly.

@christopherrobinson7541 День назад

_"Like all the facts that were censored away"_ Which facts?

@AlbertMark-nb9zo День назад

You obsessed over "facts" taken out of context. Had little experience in any experimental data. Made up theories and used FOI to push a pov and platform unproven points.

@thomasrohrer7369 День назад

Dr Racaniello is poorly informed about epidemiological topics so it is disappointing to see Dr Griffin yielding every time to Dr R's opinions. Like the one about T-cells even though all available research shows that vax protection wanes after 4-6 months. It is strange to see a presumed scientist so dogmatic in his thinking. If you want to get better insights on epidemiology of COVID etc you would be better served listening Dr Osterholm's podcast.

@bubbsy2002 День назад

Why are you here then? Stop trolling, if you have another expert with another opinion why not talk directly to the host, that would be proper IMO!

@Logotic День назад

Michael Osterholm is (very) poorly informed about virological topics and does not appear to know the difference between antibodies, which fade quickly, and cellular immunity, which doesn't. The influence he had in the early days of the pandemic was unfortunate.

@christopherrobinson7541 День назад

_"Like the one about T-cells even though all available research shows that vax protection wanes after 4-6 months."_ The protection afforded by antibodies falls as the immune response contracts. These antibodies target specific regions on the spike protein (epitopes) that move as the virus mutates. This allows the virus to avoid immunity acquired from from the vaccines and previous infection. The cellular immunity (T cells) target different epitopes on the spike protein, that do not change much between variant subtypes, so it remain effective. The upshot is that as the antibodies fall the ability of the vaccine to protect against mild disease fall, but the protection against serious disease and death, is maintained at a high level.

@francesschaefer 19 часов назад

@@Logotic imo Dr Osterholm is in a different lane, he is a public health expert.

@StefaanNijs 14 часов назад

Good advise to look for other opinions. I asked several times to invite a scientist with another opinion. Dogmatic thinking doesn't allow for that. These scientists know so much and read so much but are confined to their thinking. And draw the wrong conclusions from wrong data. It's highly likely that they have a share in selling mRNA vaccines regardless of the consequences.

@rohitramanath877 День назад

The 7 dead high-school football players. That's what doesn't fit. That's when discerning people throw away your theories.

@christopherrobinson7541 День назад

That is the way young people die. The rates of MADS now as it was before the pandemic.

@AlbertMark-nb9zo День назад

Ah an anti vaxxer. Then what was the death rate of highschool football players otherwise. What is the death rate of the disease itself. Your number is pretty useless. Recently, in the US, the percentage of deaths in Kentucky was 4-6% due to COVID of all deaths in the state.