Thank you Daniel and Vincent. This episode was especially packed with info. The study from Scotland has convinced me that it's time to lose some weight. No matter what, that's a risk factor.
I 100% agree about the language. Also I get endlessly frustrated when the term “gene” is used when allele is the correct term. The use of these incorrect terms has wide-ranging impacts on comprehension of processes and biology.
Yes mollie, and this is not the only "communication problem" that is gumming up the works as the pandemic rolls along. One giant problem is the profusion of know-it-all cable news anchors with bleached teeth who blubber and blabber and toss around terms insouciantly but they all have zero credentials, experience, or training in ANY branch of healthcare or science. It's enough to piss one off totally . . . . .
@@heeroyuy298 allele is a gene variant. We all have the same genes (location in our DNA)…within a species the genes are all the same (except for those that occur on sex chromosomes if the species has them, like we do), it is the variation in the genes that is different among individuals. For example the “Breast Cancer Gene” BRACA1… all humans have that Gene (it is, in fact, a tumor suppressor gene that regulates part of the cell life cycle in certain tissues), but SOME people have a variant (allele) that results in a faulty protein therefore a predisposition to developing breast cancer. So, use of gene instead of allele can be endlessly confusing as variants of genes are much more likely to occur during replication error than entirely novel genes. Hope that clarifies. Happy to elaborate if you wish.
I was surprised to hear Dr Griffen’s comments touting the effectiveness of the ID Now molecular kit. Many episodes ago Dr Mina correctly pointed to importance Rapid Antigen Testing over the cumbersome and expensive Molecular tests. We should be promoting The latter option at this late stage of the pandemic and encouraging free distribution of rapid tests to every house hold in the country.
Very interesting, informative and worthwhile video. With all that has happened during the past year, I'm astonished at how many Americans are unvaccinated. I fear this could cascade into a far bigger disaster.
I am a neurologist, and I have a lot of patients with multiple sclerosis who take b-cell depleting therapies (i.e. ocrevus, rituximab, kesimpta) for multiple sclerosis and other autoimmune diseases of the nervous system. We do see increased risk of disease severity with these medications, and I have three patients who were hospitalized with covid-19 who were fully vaccinated (2 doses mRNA vaccine). One was under age 25 and otherwise healthy. All three recovered. I have not had any patients with severe covid-19 after getting the booster dose (so far).
PCR reveals an Omicron case via dropout of one of the genes used to identify the virus, then genetic sequencing can be used to confirm it. In the UK we will be informed if our PCR test indicates Omicron as we are having to self-isolate if we test positive for Omicron even if vaccinated (for now at least).
The study that shows people that had Covid and recovered have a significantly higher rate of all cause mortality would seem to be another reason to support the use of boosters to prevent infection, at least for now. It’s disconcerting to continue to hear the message that the only thing that matters is that vaccines prevent severe disease and death when we we know of the dangers of long Covid, even for those who had only mild disease.
😊 thank you Doc. Dr Griffin mention that one person that went to an anime convention. I’m worried.There is one coming in LA in January and I am one of the volunteer staff. I will watch the infection trend with B1.1.529 in LA
I choose not to worry about things beyond my control that have not yet happened, after I make a quick plan, and maybe a plan B. Been avoiding media speculation on Omicron as I wait for scientific data. Very interesting about the T4 cells passed through breastfeeding, increased mortality after recovery even for mild cases, group mask protection over time being lost, and repeated rapid testing over a PCR test.
I'm wondering if I'll ever get back to the social dancing that made my life worth living, salsa/kizomba/just bouncing around in a crowd. It sounds ill-advised, for a 65 year old.
Is there a reason we can't refer to "Covid-19 long-haul" as SARS-CoV-2 Autoimmune Disorder Syndrome? If not, develop a grading system (I-V) based on severity and number of system(s) affected, including inclusion and exclusion criteria. The range would reflect from mild and most likely to resolve with minimal medical intervention (I) to severe multisystem involvement (5), which would carry the worst prognosis for long-term survival. Each category would be based on subjective clinical findings and radiologic and/or laboratory confirmation. The criteria would include newly diagnosed medical conditions affecting endocrine, nervous, and cardiovascular, etc. system involvement. Given the alarming number of past and certain future cases, we can anticipate increasing numbers of patients becoming permanently disabled, as defined in the AMA Guides to the Evaluation of Permanent Impairment. This would require the AMA guides to be updated to include the newly described condition related to the SARS-CoV-2 virus. In addition, I think such a system would serve as a valuable guide to future research and medical interventions.
Seems like not such great news from the studies on B&T cells (which sound turn out to be incorrect), but even Daniel & Vincent seem surprised. Bad news for 2 big MAbs effectiveness against Omicron. Cases in children. Interesting & unusual viewer question re vaccination & insect bites
THANK YOU DR GRIFFIN! Itchin ears now! Disappoint no Slide to SS...easier for a 69yr oldFbefore my 1st cupa jo! please pretty please &tnx HAHAHA, My Gransons wearing a BOW next "ANIME" LA July
B cell info VERY interesting for Naturopaths! Unusually I've had a coupla joints flaring up irrespective if season! Could my Bcells be in "crechendo" then? I'm buddied up with a 2nd stage dementia 84yr old male for the duration ...6monthly "rage and yelling episodes" I've had the "innoculation" I need (20mins max each) but my finger digits keep ebbing and lulling with swelling and pain.....am I "getting" it? Or just "wishful thinking" no tests my coverage pulled out long ago.
