Updates in Therapeutics for Parkinson’s Disease

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The speaker was Gaurav Chattree, MD, movement disorder specialist at Stanford. He addressed the "phase 3" or "almost phase 3" research pipeline for disease-modification treatments and for symptomatic therapies.
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Опубликовано:

30 сен 2024

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Комментарии : 15

@mantaslukosiunas6248 5 месяцев назад

Thanks for great insights! About buntanetap - they had 520 ptients phase 3, 6momths trial enrolled in record speed. Interim analysis done at 2 months mark said - go ahead, do not increase trial size. They already completed this trial. After first cleaning jobs cro cleaning center made some mistakes and found that 40-50 patients had low buntanetap plasma levels and company had to exclude those, or go ahead with them before database lock. Also, internet is full of anectodal responses how Buntanetap changed prkinsons ptients lifes. We will see Parkinsons results in June. Their alzheimwrs phase2/3 with 320 patients 3 motnhs study comes out this konth too!! Data is already cleaned

@chinko1953 5 месяцев назад

Ambroxyl , a common OVER THE COUNTER cough medicine in europe, is an orphan because it is not patentable by big pharm. Results in the UK seem very encouraging. I would love to try it. Unfortunately not sold in North America..

@alaneverett9767 4 месяца назад

Order it online

@shaynadavidovhansonrealtor 3 месяца назад

Interesting

@robert9248 Месяц назад

I use Ambroxol sustained relief capsules and fast acting with one 75mg in the AM and one 30mg in the AM. I was taking 8 sustained relief tablets of Carbidopa/Levodopa a day. I weened myself off slowly down to three tablets a day of Carbidopa/Levodopa. Initially, I substituted one 30mg Ambroxol instead. In the beginning of my “personal trial” result, every one of my symptoms fell away but sexual disfunction but I am 76 years old. Ambroxol is a mild laxative so constipation went away, in addition, sleeping too improved. My gate and balance is so much better and arm swing is back with me taking longer strides. I can run/walk 8 miles.

@robert9248 Месяц назад

I am totally off Carbidopa/Levodopa and only on a more standard Ambroxol dose, not the 10 times dose used in the 3rd Clinical Trial

@shaynadavidovhansonrealtor 3 месяца назад

How do you get a Symbyx Laser in USA? PLEASE HELP.. My dad is a deserving Veteran.. Caridopa/ Levidopa is giving him REM disrupted sleep: which entails disturbing nightmares, active sleepwalking which is very dangerous.. MEDS ARE NOT WORKING AND EXCACERBATING PD

@markprana 3 месяца назад

I think they can sell and ship to Canada, in case you have friends or relatives there. You could also try RedLightsonthebrain, who ship from Australia - they may have less export constraints. A lady in our PD group uses their product and talks highly of it.

@shaynadavidovhansonrealtor 3 месяца назад

What other drugs help or therapies if Caridopa/ Levidopa is causing severe nightmares and constipation in my HWP??? HELP!!!

@markprana 3 месяца назад

Coconut oil has seriously alleviated my constipation. I take a teaspoon in coffee 5-6 times a day. Go easy though as too much can cause very loose bowel movements. Hope this helps.

@shaynadavidovhansonrealtor 3 месяца назад

@@markprana THANK YOU🙏🏽❤️