I am a second year med student reviewing this for boards (70k/year debt, woo!). I spent many hours attempting to learn this in my first year, but I never truly understood it beyond "free nitrogen is bad, urea is good... now memorize all these random chemicals to make urea...". I literally wasted hours of my life memorizing/purging this for exams, and now, in 13 minutes, you actually TAUGHT it to me such that I UNDERSTAND what the heck is going on. You have an incredible gift... Please never stop teaching. Thank you so much for this! Best of luck with your future endeavors.
You never cease to amaze me. Countless hours of studying cut to min. because you are a pro at organizing information and conveying it. THANK YOU! The few thumbs downs are probably from jealous profs. You kick ass.
Hey, I told all my friends about you! And even now when I'm no longer studying biochemistry but focusing on Internal Medicine I'm still getting back to you to remember the basics. So thank you so much. I will never forget your help. 😭♥️
thank you so much sir !! I was studying this from Lippincott but everything was just passing over my head. now after listening to your lecture everything is crystal clear! you provide every detail necessary for tests and your illustrations are also so perfect.
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I had biochemistry structure final exam today and I hadn't studied anything because I was so sick! So I woke up very early in the morning and started watching your lectures that were related to my exam! I'm just going to say that you are amazing because not only I'm going to pass but I also was able to answer some tricky questions because of the details you mention in your lectures! Thank you very much, god bless you!
Thank you SO much for all your hard work and putting together this videos! You've helped me pass all my biochemistry classes in the University. You are so good at explaining everything. Love that everything is visual and color coded. You are amazing!!!!!!!!!!!!!
I would just like to let you know that you are a saint. One day when I have money I will be donating because you have saved me from failing my biochem courses. You deserve the world
Amazing I should really show your videos to my lecturer so he would learn how to teach better, I went to a 2 hour lecture today and didn’t learn anything, great work!
Thank you so much! You have helped me many times in my biochemistry exam! Actually, you helped me aced it. Thank you for organizing a comprehensive summary of topics like this one.
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Great video! Thank you for making this. I just have one question: What deprotonates the ammonia after it attacks the carboxy phosphate? Perhaps one of the O's on Pi does after Pi leaves? or perhaps once the pentavalent intermediate is formed after NH3 attacks, NH3+ is deprotonated to NH2 by some base at the active site, THEN the pentavalent intermediate collapses and kicks out Pi? I hope you understand what I am asking; please let me know if it doesn't make sense. Thank you!
Great! Can you tell me that if it is parts of the urea cycle product--Fumarate go to glyconeogenesis and parts of them go to oxaloacetate which convert alpha-Amino acid to alpha-keto acid and form Aspartate (a reactant of urea cycle)?
Quick question on the net rxn. I get that CO2 is converted to HCO3- using 1H2O but shouldn't the net rxn show the free H+ on the product side that disassociates from carbonic acid to form HCO3- or is it used somewhere and I haven't counted right?