Using Nukes to Help You Win In Civilization 6 

Can they use them or physically never can?

@@Therealnapoleonbonaparte_ I think they can, but not often

​@@Therealnapoleonbonaparte_They can but they normal don't, the only time I've really had the ai use them was a dom game where gorgo was did almost nothing but build nukes, it was really scary because while I had nukes I didn't have many, she ended up with like 10 of them and I frantically tried taking her out when I noticed what she was doing, luckily however the ai is stupid and she just continuously kept nuking the city center to one of my least important cities and she wasted them all and I was able to clean house with GDRs soon after. So even if they have nukes and use them, they have no idea how to actually use them lol

I usually shoot for both scince and diplomatic. But diplomatic just comes faster since I almost always get Statue of Liberty, and that the AI will still vote for you as long as they can benefit from you or themselves, even if you are at 19/20. It's also easy to outcompete AI in events granting you diplomatic scores.

Endgame civ is just a question of how long you can endure before the games endless amount of tasks make you rage quit.