Watch this video before buying skincare with niacinamide ❗ Application, effect, myths 

Niacinamide (INCI: Niacinamide) is used in many skincare products (including drugstores). But does it actually do any good or is it just another pointlessly hyped ingredient? #incipedia #niacinamide #skincare
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0:00 What can niacinamide do?
03:08 Why overall formulation is important
04:43 When do you see an effect?
06:11 Niacinamide in skin care is NOT innovative!
09:01 Niacinamide BFFs: NAG & Kinetin
10:48 Product examples with niacinamide
12:32 Does niacinamide make the skin uv sensitive?
13:31 Niacinamide checklist (application, effect, etc.)
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[Q1] Draelos ZD, Matsubara A, Smiles K. The effect of 2% niacinamide on facial sebum production. J Cosmet Laser Ther. 2006;8(2):96-101. doi:10.1080/14764170600717704
[Q2] Tanno O, Ota Y, Kitamura N, Katsube T, Inoue S. Nicotinamide increases biosynthesis of ceramides as well as other stratum corneum lipids to improve the epidermal permeability barrier. Br J Dermatol. 2000;143(3):524-531. doi:10.1111/j.1365-2133.2000.03705.x
[Q3] Shalita AR, Smith JG, Parish LC, Sofman MS, Chalker DK. Topical nicotinamide compared with clindamycin gel in the treatment of inflammatory acne vulgaris. Int J Dermatol. 1995;34(6):434-437. doi:10.1111/j.1365-4362.1995.tb04449.x
[Q4] Bissett, DL; Miyamoto, K.; Sun, P.; Li, J.; Berge, CA Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin. Int. J.Cosmet. Sci. 2004, 26, 231-238.
[Q5] T Hakozaki, L Minwalla, J Zhuang, M Chhoa, A Matsubara, K Miyamoto, A Greatens, GG Hillebrand, DL Bissett, RE Boissy, The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer, British Journal of Dermatology, Volume 147, Issue 1, 1 July 2002, Pages 20-31, doi.org/10.1046/j.1365-2133.2...
[Q6] Boo YC. Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Antioxidants (Basel). 2021;10(8):1315. Published 2021 Aug 21. doi:10.3390/antiox10081315
[Q7] Kimball AB, Kaczvinsky JR, Li J, Robinson LR, Matts PJ, Berge CA, Miyamoto K, Bissett DL, Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N‐acetyl Glucosamine: results of a randomized, double-blind, vehicle-controlled trial, British Journal of Dermatology, Volume 162, Issue 2, 1 February 2010, Pages 435-441
[Q8] Chiu PC, Chan CC, Lin HM, Chiu HC. The clinical anti-aging effects of topical kinetin and niacinamide in Asians: a randomized, double-blind, placebo-controlled, split-face comparative trial. J Cosmet Dermatol. 2007; 6(4):243-249. doi:10.1111/j.1473-2165.2007.00342.x
[Q9] Final Report of the Safety Assessment of Niacinamide and Niacin1. International Journal of Toxicology. 2005;24(5_suppl):1-31. Doi:10.1080/10915810500434183
[Q10] Surjana D, Halliday GM, Damian DL. Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in human keratinocytes and ex vivo skin. Carcinogenesis. 2013;34(5):1144-1149. doi:10.1093/carcin/bgt017
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