What is the longest match between the human and chimpanzee genomes? 

Listening to you makes me feel like I am on the cutting edge with you! Keep it up, this is some of the most important research to be done at this time...Les

Thoroughly enjoyed this. Nicely done, Rob! 😎👍

The video doesn't seem too bouncy at all and the spring colors are beautiful. ❤

Many thanks for your dedication, it's most appreciated.

Always learning from your "lessons". Keep going Rob. Don't do for us but for God's glory. You are doing awesome.

These videos are a joy, Dr. Carter! God bless you.

@Biblical Genetics, What those of us in Genetic Genealogy do is look for our relatives based upon Shared Autosomal DNA Centimorgans. The more you share, the closer the relationship. One Centimorgan is equal to 1 million base pairs. We also use mitochondrial and Y-DNA for more distant ancestors.

There is no 'the' human genome, nor 'the' chimp genome. Individuals of both species have distinct genomes. How much alignment is there between two distinct humans? If you are _really_ interested in this question, such comparisons are quite common between species, and there are a lot of tools that already exist to make these comparisons. Also - just what does this actually tell you? What is the point of such a specific _kind_ of alignment? If there is a change in the genome, but not in the resulting protein sequence, is that really a meaningful difference? Why leave out insertions? Or deletions? Oh - and if there are 4 possible bases, plus an 'N', then you cannot use pairs of binary digits, because there are only 4 ways to make a pair, but you are looking at 'A', 'T', 'C', 'G', and 'N'. So - it sounds like a major problem in your process. While you might be a good programmer, your are not really doing biology here.

Great video! Enjoyed it immensely! It sounds like you've done a lot of hard work on this. Don't sweat it. These genomes are huge. Even with tools like BLAST to help you. I especially like what you had said about the unalignable differences and having to add those back in and the percent similarity will drop. This is what I've been saying since the beginning of this controversy. God bless!

Really interesting, t hank you, sir.

This video was so fun to watch; you're brilliant!!!

Apart from the simple sequential base model, how much match is there in the topological model? Not just the location of histones, but also megabase domains and even chromosome location?

I believe I can help if you want me to take a stab at this. I ran sequence analysis (as a hobby) on e coli way back in the late 80s. My code would be in C or C++, operating on a PC.

I like the background in how you went about doing things and I also like how you qualified what it would mean. It is easy to say that since there is no long commen strand therefor they are not related. But that is obviously a false argumentation, no matter if the conclusion is correct or not.

There's no polite way to tell people they've dedicared their lives to an illusion." RIP Daniel Dennett

Among the first thousand prokaryotic genomes that were sequenced, not a single protein coding gene is conserved across all genomes. LUCA bites the dust.

98.8%

Assuming 1) 5% difference between genomes, 2) that all these differences are spread uniformly, then the size of longest match is 1 / 0.05 = 20. I reckon this is also low bound for it in general (for same-size strings). High bound on size longest match for any non-uniform differences can be up to 1 - 0.05 = 0.95 part of the genome, e.g. when all the mismatch is in the end/beginning. Considering that mutations are approximately uniform, the size of longest match should be near the lowest bound.

A fool on his errand...

No new species: How to maintain speciesism Reproduce your genome until it creates the species Btw the plants doing specific polyploidy functions MAINTAIN the species How is it that a cockroach and rats can reproduce, after nuclear radiation,with mutations such that they become multi ploidy in order to maintain morphology and function and RNA or DNA have primacy or a selective function? Where in the genome does a spider make its web? Where in the genome is the code for morphology? If form is function and function is what is selected for and morphology is not coded for then what is being selected? If a flatworm can be mixaploidy and maintain function and morphology how does DNA have primacy? If the fewest genes that a cell can have to sustain life is around 400 but it has to have additional DNA to have reproductive function how can RNA or DNA have primacy ? If it takes 400 genes to simply maintain the life of a cell then how did 400 genes of function either come about and how could that matter if the cell couldn’t replicate? What was the function of the protein that was first coded by RNA or DNA from which a selection could be made? One functional protein much less 400+ Many are now attempting to explain top down vs bottom up. Strong Emergence and other outlandish ideas to explain away what they refuse to acknowledge. They have left the door wide open for the discovery of mechanisms by which God spoke everything into existence. The evidence is piling up that species have mechanisms in place which allow for species stabilization rather than change. Flatworms keep all their mutations and yet do not change their morphology. Rats and cockroaches were the first to return to South Pacific islands where atomic bombs were tested and those creatures did not change morphology/species. They became polyploid in order to maintain the species. They have known this since the 1950s yet you never hear about it because it clearly goes against the paradigm. A recent redo of fish classification turns these mechanisms on their head. Dissimilar morphology appears to be closely related genetically throughout new classification based on genetics, Completely rearranging classification based on morphology. What it shows is that fish are fish! Fish adapt with similar morphology but different genetic based on environmental conditions. However they always are fish. Tortoise have different patterns on each individual species. These patterns are like patterns on chladni plates. Such vibration patterns indicate that each species is iterated based on a specific vibration pattern. They are quite literally spoken into existence as individual species. There is no mechanism in which a vibration pattern is transmitted via genetic modification. Consider that on a chladni plate the node-anti-node patterns are determined by the frequency, the shape and material of plate and the material vibrated( sand-etc.). However it is dominated by the frequency. Patterns are not continuously changing. You might have to range between a large frequency to get any other pattern. Plant morphology too exhibits thus vibrational function as differences in species.

Biblical genetics is an oxymoron.

don't forget to do the control. that is random human vs random human.

Ok, you do you