Please find attached the live recording for Anaesthesia Coffee Break and Adrenaline Memories with myself and Dr Lahiru Amaratunge.
Discussion was based on the 2016A2 Question, Discuss the factors influencing the speed of onset of blockade, of a major peripheral nerve, with local anaesthetic.
Highlights are:
1) Answer should based on Fick's Law of Diffusion
2) Lipid solublity is related to Protein Binding
3) Lipid solubilty is also related to Potency
4) 10^(pH-pKa) / [1 + 10^(pH-pKa)] calculates the unionised fraction for bases
5) In order, nerve Types and their sensitivity to LAs should be B, C, A delta, A gamma, A beta, A alpha
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Disclaimer:
The information contained in this video/audio/graphic is for medical practitioner education only. It is not and will not be relevant for the general public. Where applicable patients have given written informed consent to the use of their images in video/photography and aware that it will be published online and visible by medical practitioners and the general public. This contains general information about medical conditions and treatments. The information is not advice and should not be treated as such. The medical information is provided “as is” without any representations or warranties, express or implied. The presenter makes no representations or warranties in relation to the medical information on this video. You must not rely on the information as an alternative to assessing and managing your patient with your treating team and consultant. You should seek your own advice from your medical practitioner in relation to any of the topics discussed in this episode. Medical information can change rapidly, and the author/s make all reasonable attempts to provide accurate information at the time of filming. There is no guarantee that the information will be accurate at the time of viewing. The information presented here does not represent the views of any hospital or ANZCA.
12 сен 2024
