When Ancient People Changed Their Own DNA

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References: docs.google.com/document/d/1X...

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18 янв 2023

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Комментарии : 855

@lutilda Год назад

This also reminds me of the cultures who are able to hold their breath longer due to their history of sea diving for food.

@christopherfisher128 Год назад

And those in higher altitudes developing more efficient oxygen processing

@marjanperveinis8355 Год назад

@@christopherfisher128 Sherpas are the people of the Himalayas mountains. A 2010 study identified more than 30 genetic factors that make Sherpas' bodies well-suited for high altitudes, including EPAS1, referred to as the "super-athlete gene" that regulates the body's production of hemoglobin, allowing for greater efficiency in the use of oxygen.

@icarusbinns3156 Год назад

Isn’t there a small culture of pearl divers that can control their pupillary constriction rate?

@christopherfisher128 Год назад

@@icarusbinns3156 It isn't Pupillary, that is the eyes, but you're not wrong. The Bajau divers in Southeast Asia, have significantly larger spleens than other non-diving individuals of even recent genetic similarities, & can hold their breath for over 5 minutes. The "Jury" is still out on this as far as an evolutionary adaptation or a result of heavy usage & their hyper-specific culture. For comparison, the Shima peninsula of Japan is home to the Ama, which are mostly female pearl divers, who can withstand long periods under water but have no major physical differences. A series of automatic responses kick in, constricting blood vessels, increasing blood pressure, and causing their heart rate to drop. While diving, pearl divers often see their heart rate at half its resting value, even though they’re swimming hard. And lastly, there is Wim Hof who can not only hold his breath for a ridiculous amount of time, but withstand subzero temps without clothing. so, I guess with dedication & practice anything is possible ;) Cheers

@icarusbinns3156 Год назад

@@christopherfisher128 I know it’s eyes. I wish I could remember the documentary I saw it in, but they can consciously control the size of their pupils. That muscle response isn’t involuntary for these people

@jackfishthe6th373 Год назад

If I am not mistaken humans habits of consuming alcohol for thousands of years was also a cultural pressure that resulted in a difference of people who can effectively process alcohol inside their body. There are some culture groups who will experience worse symptoms of alcohol poisoning (nausea, headache, facial flushness) than most other cultures worldwide. The name of this is an Alcohol Flush Reaction which has also been known to be referred to as the "Asian Flush".

@TragoudistrosMPH Год назад

Eons did a video on that, but primates can universally process alcohol. Humans ave extra copies compared to most others, but some human populations vary, like you're referring to. (No one is seriously harmed, but other animals are easily harmed. An elephant could almost die drinking what even a alcohol sensitive human could easily drink)

@Makabert.Abylon Год назад

If im not mistaken asians can have that variant that makes them extra sensitive to alcohol

@EdepolFox Год назад

@@Makabert.Abylon While I'm not saying this isn't true, I've never heard it before and I'm not gonna trust something like that without a source. Also, asian cultures have consumed alcohol for as long as everyone else. In other words, that wouldn't be relevant to culture impacting evolution, that would just be a mutation that causes an intolerance to something.

@richardb22 Год назад

I have a bit of Irish in me ?😃

@Nate-.- Год назад

@Edepol vox has a short video on asian flush, something about immune response to more of a biproduct when they digest alcohol. But it doesnt affect everyone northeast asia

@nerdlarge4691 Год назад

Glad that they mentioned Adult Lactose Tolerance evolved in multiple human populations independently throughout Eurasia and Africa.

@samsmith4242 Год назад

5 times, though the European version is currently the most common

@CordeliaWagner Год назад

Disgusting.

@aaron2891 Год назад

Until this video, I genuinely thought it was only Europeans

@samsmith4242 Год назад

@@aaron2891 Europe, Twice in sub-Saharan Africa, the Middle East and Central Asia

@alessandro.calzavara Год назад

@@samsmith4242 Could you please tell me the groups? I know Northern Europeans and Fulani but I wasnt aware of others

@ComputerGarageLLC Год назад

I wonder if someday someone will research our gene in relationship to addiction. We have been producing alcohol (mead, ale, wine) for a long time. Might give it a better understanding why some people react differently to it.

@worldsboss Год назад

Alcohol is actually a great example, as it’s toxic to our bodies and we’re not really intended to consume such high quantities of it. Interesting to think about what effect it may have on our genomes!

@JV-pu8kx Год назад

@@worldsboss Also with spicy foods. The chemicals deter most other animals from eating the plants, but not us humans.

@tara44789 Год назад

People who come from regions with longer exposure of alcohol such as Italy, have lower rates of alcoholism. Vice versa.

@BleedForTheWorld Год назад

@@tara44789 big if true

@mad.psyence Год назад

Some cultures are missing the gene that helps your stomach metabolize alcohol more efficiently (they produce less of an enzyme needed).

@lektraburux Год назад

I’m jumping up and down at the citing of Padró et al. Such a great paper, proving the explanatory power of the cactophilic Drosophila model. I work at Evolution Lab at UBA-CONICET, so this was one of the few times I knew the people you cited. Excellent video as allways. Thanks! 🌵🪰

@atamburlaine 10 месяцев назад

Please tell me more about what he's working on?

@lektraburux 10 месяцев назад

@@atamburlaine who do you mean? The author?

@LimeyLassen Год назад

I'd say songbirds are a great example of culture and evolution intertwining. Male songbirds spend a lot of time practicing their technique and memorizing and imitating other males, so it's not just genetic. But their capacity to do so is.

@zs9652 11 месяцев назад

Some species of ants have also learned how to farm and evolved around that. So they have their own culture affecting their evolution.

@JCF69700 Год назад

so, maybe one day our descendants will have genes to digest microplastics and breathe nanoparticles 🤔 ?

@TragoudistrosMPH Год назад

We'll probably have to create that gene artificially... It would be worth it to save ourselves...

@bennu547 Год назад

🙄

@madcow3417 Год назад

*safely

@julianaylor4351 Год назад

There are bacteria that can break down some plastics, so if they got into our stomach and gut biom, that could happen.

@_____alyptic Год назад

@@TragoudistrosMPH Something even if it happened, wouldn't really help us. CRISPR is big but it doesn't really have any effect on people already around.

@TragoudistrosMPH Год назад

Please do a full episode on Lactase Persistence. It's so poorly understood, and so many people think they are just sick, or keep drinking milk thinking it's healthy for them. Northern Europe and Central West Africa are where 2 of the main genes mutated. A 3rd in the middle east that's not strong exists too. Asia, Americas, Australia, and Pacific regions don't indigenously have such a gene, unless they are descendants of one of the above people with the mutation. Super fascinating and a great PSA.

@nunyabiznes33 Год назад

I'm Asian and still drink milk almost daily. Albeit to just a glass a day. I haven't dared chugging down a gallon.

@morgan0 Год назад

afaik it’s not unhealthy to consume dairy if you’re lactose intolerant, but i’m lactose tolerant so i don’t have experience with that. i do have experience consuming allulose and sugar alcohols in decent quantity and that seems like it could work pretty similarly, basically as long as you have enough in your diet your gut will adjust to the fermentation of them, eating it when you don’t consume it much would cause more issues because your gut isn’t used to it

@ginnyjollykidd Год назад

Lactose intolerance can cause a person to develop diarrhea and stomach upset. Intolerance is not the same as allergy. It's not Anaphylaxis. But it can still make you feel really bad. It's not the only thing that can make you feel bad drinking milk. There are times when dairies give a lot of antibiotics to their cows. I think more and more these days the do it only if they need to keep the herd from catching a disease. But I can tell if there's been an increase in antibiotic use: I get diarrhea like when I take antibiotics. And it doesn't matter the milk. Acidophilus milk at the time still gave me diarrhea. So for a while I got Simple Truth Kroger brand because it uses milk from only grass-fed cows and has no antibiotics. And it agrees with me just fine. A container of milk can say on the label all it wants about not using antibiotics, but you can't fool my body.

@brooklyna007 Год назад

You missed the herding populations of east Africa that drink milk multiple times a day and have been doing so for thousands of years. For example, the Maasai people in Kenya are definitely lactose tolerant.

@ragnkja Год назад

@@morgan0 It’s not that it’s unhealthy (unless it leads to terrible diarrhoea and dehydration), it’s just very uncomfortable.

@Summer-xe6in Год назад

Thinking about the amount of work that has to go into making this video blows my mind. The narrative and narration was excellent. This was a fun video to watch. Complex yet not too deep that I had to repeat 5x (only 2 times for me in some areas lol). Thanks to everyone involved in this video (and yes that means patreons and all) ;)

@mgaus Год назад

Here's hoping we continue to shape our future with considered and measured steps

@Unpainted_Huffhines Год назад

No, return to monke

@jamesglosangeles Год назад

By measured steps you mean "quarterly profits", right?

@LuisSierra42 Год назад

@@Unpainted_Huffhines reject humanity

@3nertia Год назад

Capitalism doesn't work that way heh

@eve5909 Год назад

Most likely genetic editing and then AI hive mind.

@H._sapiens Год назад

This is an excellent episode that communicates a complex topic with all the right nuances. It doesn't generalize the evolution of lactose tolerance to "us" or "humans", which is how the topic of lactase is usually presented. I love the examples of genes for the breakdown of starch and genes for processing hallucinogenics, so those of us from lactose intolerant populations have some examples of our evolution being shaped by culture too.

@nmarbletoe8210 Год назад

90 likes

@bobbun9630 Год назад

Genes that affect the expression of proteins useful for processing toxic alkaloids need not have been selected for on the basis of ceremonial usage of hallucinogenic cacti, though. That same region of South America is where the potato originated, and potatoes contain solanine, chaconine, tomatine, and possibly a few other toxic alkaloids. More ancient varieties would likely have contained a lot more of those compounds than modern varieties, and I think it's pretty safe to suggest that many more potatoes were eaten than cacti.

@stinew358 Год назад

Yes, although humans have methods of removing the alkaloids in potatoes (cooking and soaking) while they intentionally digest the cactus

@olha_ Год назад

That's a really interesting insight, but can you cite a source please?

@bobbun9630 Год назад

@@olha_ Most of my comment is semi-speculative in nature. I'm not saying that gene expression related to processing plant alkaloids definitely was driven by potatoes rather than cacti, merely pointing out the plausibility of that as an alternative explanation. However, if there's a specific claim you want to have cited, identify the claim more precisely and I'll see what I can find.

@olha_ Год назад

@@bobbun9630 it's the very statement that gene expression for alkaloid processing is influenced by the potatoes rather than cacti. I totally agree that this is more plausible from a common sense perspective but was wondering if there are any studies or further reading on this. Thank you!

@vguyver2 Год назад

One of these days this channel will need to cover the Moken people (aka as sea-nomads). They have partially adapted to be able to see underwater far easier than the rest of the human population.

@justsomeguywashwd_jbm821 Год назад

Whilst watching this, I remembered those ants that farm a type of fungus, & wondered if they have have had an effect on their genome in a similar way to what was described in the video with regards to humans.

@jeffreybright6354 Год назад

Probably became more sensitive to detecting the pheromones that fungus releases instructing them which foods it needs and which stuff they brought is poison. I keep telling people the world is really like pokemon/avatar, the complexities of the creatures and ecosystems around us are awe inspiring

@astick5249 Год назад

@@jeffreybright6354 Its funny because Avatar's world is heavily inspired by the intertwined ecosystems of earth.

@TheNightshadePrince Год назад

They have their own culture of fungus that doesn’t grow naturally and they are a separate species of ants so yeah. :)

@daveballjoint5285 Год назад

This all rings so true. My people have specially adapted very quick pupil contraction and dilation which aids in quicker identification and capture of prey in late night visits to the refrigerator. Speedy pupil dilation following the closing of the fridge door aids in safe navigation of dark hallways and stairwells. Love your videos. Miss your podcast. Keep up the great work!

@SimonsDiscoveries Год назад

Takling about cacti and showing a Euphorbia instead... Twice! 6:21 and 8:21 Come on guys!

@generalputnam2990 Год назад

Convergent evolution.

@BEATINGYOU Год назад

The kids that open their eyes in the ocean to hunt and they dilate as you watch to adjust to seeing underwater is mind blowing

@erikjohnson9223 Год назад

In discussing "cacti," y'all showed a succulent euphorb. Eating that would kill you rather than make you high.

@nmarbletoe8210 Год назад

you wouldn't experience euphorbia?

@semaj_5022 Год назад

This may be one of my favorite episodes yet. Such an interesting topic and very well presented. You guys are awesome!

@dennisud Год назад

I was so surprised to see your old and up to date video posts on the Local Now App! I love watching these on a bigger TV than on my smaller monitor! Congrats!

@leeleaman8057 Год назад

Thank you for the fantastic video Michelle! And the rest of Eons :)

@violentbenevolence Год назад

Seconded. Love their content

@ellisonrhea4854 Год назад

Our built environments are such a huge part of our cultures that definitely change pressures on us as well. By enclosing ourselves from biodiversity, we're totally changing our relationship with both beneficial microbes and pathogens. There's a fascinating book on this topic called Never Home Alone by Rob Dunn. It's probably too soon to know what these changing pressures are doing to our genetics, but I can imagine the process will reward those who can do better with fewer lil friends and more lil enemies.

@chandekam1826 Год назад

Isn't the role of culture in shaping DNA really common across animals? I mean, so many animals have body decorations, exaggerated body parts, behavioural traits (esp. courtship), nest building techniques, and so many other things only because of potential mates preferring things a certain way. I think culture plays a massive role in plenty of other animals.

@abiku2923 Год назад

I think how the video addresses this is specifying how regularly humans do this. Making different kinds of termite mounds doesn't cause genetic change very often, if at all. Countless changes in humans in just the last 10,000 years, but also consistently going back another 400,000 years.

@christopherfisher128 Год назад

The only real difference is that humans can do it on purpose. Look at "cultures" that developed after long periods in "extreme" environments. High altitude, deserts, the Arctic, Primarily animal based diets, & even island or urban populations.

@sillyjellyfish2421 Год назад

That was my first though as well. There are survival pressures (consumption of poisons, novelty food sources, dangers of new environments) where the survival comes from literally not dying before reproducing. And then there are cultural pressures such as atractiveness of sexual partners, social bonding within the group, co-parenting and so on. In these cases, the question isn't whether an idividual dies or not, but how successful they are in securing a mate and raising the next generation up to their adulthood.

@Dinofaustivoro Год назад

Yeah. I really dont think there is any fundamental diference between human culture and any other animal behaviour

@karawethan Год назад

@@Dinofaustivoro The fundamental difference is that most of those animal behaviors are instinctual, whereas human behaviors associated with culture are all learned. That's really what culture is -- collective knowledge that's passed down from one generation to the next. A break in that generational chain means that knowledge is lost forever until it is (maybe) rediscovered.

@Warstub Год назад

This is an absolutely fascinating subject. Thank you for exploring it.

@jacobs8959 Год назад

Wow this was so interesting! Thanks for sharing!

@Ricee__ Год назад

time to get wings

@MonkoK14 Год назад

Imagine how tiring it would be to flap them though

@Ricee__ Год назад

@@MonkoK14 ez, u just try harder

@MonkoK14 Год назад

@@Ricee__ true

@DFloyd84 Год назад

I've been drinking cases of Red Bull, but I haven't gotten wings. Just kidney failure.

@harveytheparaglidingchaser7039 Год назад

Great episode! Beavers come to mind. They build their own niches... And fruit eating birds and tapirs dispersing seeds and growing forests. Are there other animals that do the same?

@Lexivor Год назад

Read "The Extended Phenotype" to find a lot more examples of this phenomenon.

@SebastianMidence Год назад

they mispronounce john davison ng's name every dang time and he STILL gives them $150 a month. shoutout to a real one.

@LolaJohnsonmusic Год назад

I love EONS!!🤯

@chloesilva8794 Год назад

Fantastic sci comms per always!

@AuthenticDarren Год назад

If you do make a video on lactose tolerance don't forget to include certain domestic animals, like cats, who also gained adult lactose tolerance by living alongside humans.

@TragoudistrosMPH Год назад

I've never heard of a gene for that, just anecdotes from people who say "we've always given our cats milk". Cats who drink milk have indigestion and loose stool. A gene has to randomly mutate and be passed on, it can't be 'gained' by drinking milk.

@nunyabiznes33 Год назад

@@TragoudistrosMPH I dunno, one of my cats go loco when he sense me getting milk before bedtime. Like, he'd bug me until I finally give up and give him what he want. His stool still firm. The other cat don't care about milk and only drank some when she was pregnant.

@AuthenticDarren Год назад

I personally have cats regularly scratching (waiting patiently really) for their daily dose of milk.It's you who believes in old wives tales Thagou.

@nmarbletoe8210 Год назад

@@TragoudistrosMPH Just a guess, but I think that cats often get fed WAY too much milk. By weight, a capful for them is like a half cup for us.

@textbooksmathematicstutorials Год назад

Excellent Video. Very Accurate!

@seriouslypagan6904 Год назад

This was really amazing; I love this channel.

@ponyote Год назад

Fascinating. Thank you.

@gl15col Год назад

Let's hope we manage to adapt to the huge amount of "Forever chemicals" they just found in freshwater fish. Might as well eat up tho, as we are already full of microplastics...

@JL-uu3lv 9 дней назад

Forever chemicals are everywhere, not just fish. Every baby born now has forever chemicals in their body

@austinharris5346 Год назад

Incredible. I was literally just thinking about this very topic last night, and Lactase persistence was exactly what came to mind... One of the best episodes, really! Loved it, and, of course I'm happy to see the sponsorships coming in, you guys definitely deserve it, but... isn't this... PBS? Kinda unsettling seeing that kind of paid programming under the PBS banner, idk...

@lindenshepherd6085 Год назад

I'm guessing it's because PBS needs the RU-vid shows to support themselves instead of giving them full funding. It's a way to enable more creativity in new platforms without having to spread the budget too thin.

@longline Год назад

This makes me think about animals that engineer to craft their niches. Elephants curating grassland by removing trees, beavers and their whole deal, termites farming fungus, there's probably a smart fish I don't know about, etc

@ortuignis3782 Месяц назад

It's me I'm the smart fish nice to meet you

@hooliganbubsy7298 Год назад

It's actually insane how interesting humans are once you look at them like any other animals. We basically removed most of our instincts and replaced them with culture which basically allowed us to adapt to any environment. Other animals took many generations to develop new instincts but we took just one. Nowadays it's a negative because the world changes so quickly but back then it was a truly miraculous advantage that only a few animals could possibly imagine.

@Dinofaustivoro Год назад

I agree! But I think it is unscientiffic to assume our culture is somehow not a product of enviroment and evolution

@hooliganbubsy7298 Год назад

@@Dinofaustivoro Culture is most definitely a product of our environment and evolution. I don't where you thought I was denying that.

@nmarbletoe8210 Год назад

i think maybe we've kept most of our instincts but added layers of culture

@williandalsoto806 Год назад

The way Michelle says Chile and Argentina is so nice!

@maclinkastex3059 Год назад

I could tell she says "Argentina" in the exact same way an argentinian would do it. Makes me wonder if she was born there.

@LuisSierra42 Год назад

@@maclinkastex3059 exactly my reaction. At the very least, she has latin roots

@H._sapiens Год назад

@LuisSierra42 Michelle does have Latin roots. They are Latinx.

@TheKeksadler Год назад

as an English-only speaker, I had a moment of whiplash and didn't catch Chile at first lol

@Lucius_Chiaraviglio Год назад

Plenty has been said about us shaping dog genetics, but what about dogs shaping our genetics?

@Klorg-ph9ib Год назад

Hey, I love your videos and have been watching them since I was in high school, and they stay with me as I’m at college. I have been thinking about this for the past few days, and notice that you haven’t made a video on this yet: how did insects go from many-legged creatures to ones with just six? How did insects lose their legs?

@Lexivor Год назад

This is a fascinating question but I doubt they'll do a video on it because I don't think anybody knows the answer yet. The origins of insects are still pretty mysterious.

@egg7247 Год назад

Fun fact, we aren't the only species who's evolution was driven by culture. This type of evolution is also very prevalent in orcas, more-so than most other species besides ourselves.

@nmarbletoe8210 Год назад

Hawaiian crows, also

@SassyGirl822006 Год назад

Interestingly, my youngest son was born lactose intolerant (we finally found out why he was so sick, and not growing at 4 weeks old). He has actually been slowly out growing it though. He can now tolerate regular cheese and yoghurt (which has very little lactose thanks to the bacteria that creates it). And he can tolerate some regular cream and milk used in cooking. But I don't push it too much, because the tummy troubles aren't worth it.

@Kobolds_in_a_trenchcoat Год назад

Wow, I've never heard of an infant who was lactose intolerant. That must be hard. I'm pretty sure I'm lactose intolerant myself and it is basically only triggered by milk and ice cream. Butter, cheese, sour cream, and other dairy products that are more processed don't set me off much. I'll still eat ice cream anyway but I'm old enough to understand the consequences. Jokes aside, I'd experiment a little with dairy products to see what does and doesn't work well once your son is old enough to get to the toilet on his own. I'm not a doctor but I don't think small amounts would really hurt.

@abelhapedras Год назад

babies are born with an immature digestive system. some (rare) babies are born without the ability to properly produce lactase, and as they grow and mature, they slowly become able to produce more of it. I was such a baby xD

@wendys9500 Год назад

I’m wondering how that works if a baby needs to breastfeed. Would they react negatively to breast milk?

@SassyGirl822006 Год назад

@@wendys9500 yes. Because all mammal milk contains lactose. Babies born with lactose intolerance used to just slowly starve to death, in what was known as failure to thrive (one cause of). These days babies with lactose intolerance can be given lactose free formula.

@jimspace3000 Год назад

Wow this was one of your best videos! You make evolution a compelling and inviting topic!

@mafarmerga Год назад

Recent research expertly explained. Thanks.

@laurenlobello2948 Год назад

That’s fascinating!

@diogoberjano29 Год назад

I did a presentation on this last Friday lmao even the graphs are the same ahah love it

@baddabing4494 Год назад

Organisms really are just like water: we always eventually change shape to fit our environment, and we're never in a stabilized state. We're always changing.

@Pottery4Life Год назад

Just another great episode. Moar of this plz.

@kike_zeron Год назад

I love this channel so much!!!!! The level of beauty explaining it all!

@AveryMilieu Год назад

Years ago I woke up in the night saying, "I believe in Quantum Evolution!" You have essentially proved that my belief is not folly. Thanks.

@juniormynos9457 Год назад

Dogs are also capable of consuming relatively high amount of starch. Do they have multiple aym1 genes or do they have other adaptations that allow for the trait? Also did humans relationship with dogs also similarly change their evolutionary pathway?

@BananaCake26 Год назад

Dogs are bred by humans, of course we changed their evolution. Look at breeds like pugs who suffer from chronic diseases right out of the womb because of the unnatural selection of breeding

@nmarbletoe8210 Год назад

cats also seem to digest rice well, so i was wondering the same question with them

@boopyboop0 Год назад

Ohhh such an interesting video!

@gailaltschwager7377 Год назад

Thank you!

@mattikallio4812 Год назад

This was very interesting.

@sapphirII Год назад

The alkaloid one made me remember. In history class, it was said that when Europeans came to the Americas and brought alcool, while we were more resistant, the indigenous population was more susceptible to get drunk and addicted. If it's true, I don't know, but I remember it was said

@generalputnam2990 Год назад

Simple carbohydrates vs. complex carbohydrates.

@egrettacaerulea Год назад

Pretty sure everyone was at least drinking corn beer. Regionally, pulque is a thing, too. I checked, there's a Wikipedia article on Alcohol and Native Americans that includes a variety of starchy substances pre Colombian cultures fermented.

@christianfrommuslim Год назад

One of the most interesting gene transitions is the loss of Y chromosome diversity as aggressive groups became dominant across large expanses. What might the world be like if it were not the aggressive Ys that won?

@user-jr6zq8gb6q 6 месяцев назад

UUAUUU!! I LOVED THIS VIDEO🤩💯

@curtiswfranks Год назад

Do humans have an evolutionary attraction to fire? Other animals do not seem to behave as we do.

@nmarbletoe8210 Год назад

yeah totally. few animals approach fire.

@Rylact. Год назад

Love the human episodes! (And the others too)

@dmonvisigoth1651 Год назад

They're gettin the bees high, man! That's the kind of science we need more of!

@susannjarvis5587 Год назад

Fascinating.

@iambiggus Год назад

Interesting! Great watch as always!

@kambojarian Год назад

Thanks!

@pierreabbat6157 Год назад

One of those graphs mentions the Barí people. I've met Bruce Olson, who's lived among the Barí (aka Motilones) for decades.

@akumaking1 Год назад

So how’s the current trajectory for humanity?

@hailholyghost Год назад

look up Idiocracy (2005)

@victorvonsteuben1728 Год назад

We are all going to die. That's the prognosis

@TragoudistrosMPH Год назад

Josh, are you trying to depress us? 😜

@DFloyd84 Год назад

Screaming toward self-inflicted obliteration, last time I checked.

@stephanieyee9784 Год назад

I found this video and topic really interesting on a personal level. I am lactose intolerant and have known this since about 1990 when it was confirmed by endoscopic biopsy. My mother cried and apologised for making me, and my siblings, drink a pint of milk every day. Haha. I am 38% Asian on my paternal side and told her it wasn't Her fault. Her mob are Anglo Celtic milkmaids and brewers.

@cheddarbeansoup Год назад

PBS uploads save my evening each and every time

@LanceHall Год назад

The children who could continue to drink milk obviously had a survival advantage.

@Linkfan001 Год назад

An advantage that would not matter if husbandry was not invented... how are you missing the point this badly?

@jryoung5460 Год назад

Likely fewer broken bones resulting in a decrease of deformities/infections.

@kendallbein5616 Год назад

Wow that comment at the top of this thread sounds like a dog whistle to racists.

@itwasagoodideaatthetime7980 Год назад

@@kendallbein5616 How is the ability to drink milk a 'dog whistle' to racists?

@9051team Год назад

@@kendallbein5616 racist against what? Lactose intolerant people? You're funny.

@leestuurmans2837 Год назад

fascinating!

@grkuntzmd Год назад

Interestingly, dogs produce much more amylase than their wolf cousins, even though they are technically the same species. Wolves have a much more carnivorous diet than dogs, so dogs have evolved to tolerate starches like their human companions.

@moreli2001 Год назад

Almost everyone with indigenous ancestry in my family (Argentina) is lactose intolerant, simply because in the New World, people didn't drink cow's milk until colonization. If you were born in latinoamérica, from a mestizo/indigenous family, it can probably be common cause of lactose intolerance.

@madderhat5852 Год назад

It's the cows, man. The cows are not what they seem.

@oneshothunter9877 Год назад

😁

@madcow3417 Год назад

ಠ_ಠ

@madderhat5852 Год назад

@@madcow3417 Oh,man, now you're following me? I won't tell anyone.

@therealjjs5656 Год назад

Thank you

@awkonradi Год назад

What a great RU-vid channel!

@zaco-km3su Год назад

Interesting!

@kaitlynoddie9649 Год назад

what i’d like to know is how i ended up lactose intolerant when nobody else in my family is. my lactase genes just didn’t get the memo apparently

@necessaryevil455 Год назад

I wouldn't go getting any paternity tests.

@kaitlynoddie9649 Год назад

@@necessaryevil455 unfortunately i was a petri dish baby so i know exactly who my dad is (barring a career ending mistake by the fertility specialist)

@rosiehawtrey Год назад

@@kaitlynoddie9649 I'm blue eyed. Blue eyes recessive. Parents and sibling brown eyed. I just got a double dose of blue eyes. And of course every cancer gene there is.. 5th BCC and breast cancer simultaneously is so much fun. I would guess both your parents carry the gene for intolerance but recessively (it didn't express in them because they only got one copy of the gene (s)). The other option is spontaneous change, which is also possible - there is more likelihood of genetic changes in "test tube" babies - they think because the process is actually stressful to the embyro... In my case the gene damage is as as a result of my sperm donor - worked in agrochem his whole career - DDT, Dieldrin, the ingredients of agent orange, paraquat, diquat - you name it. Cleaning up spills with yard brooms and a garden hose.. 🤦‍♀️. My three young neices probably have the same genes - yay for dead before 30.

@BananaCake26 Год назад

Milk is disgusting, you're not missing much

@kaitlynoddie9649 Год назад

@@rosiehawtrey interesting, i didn’t know that but it makes sense that ivf would be stressful to an embryo

@casek6930 Год назад

I find the modern, hyper complex and constantly changing techno-culture to carry with it a heavy cognitive load. It seems to be hovering around the threshold of what a human can keep up with. I find myself unable or unwilling to do it. And the older I get, the less willing I am. So it appears that there is a very strong selection pressure at work that favors youth and high intelligence. I suspect that this will create greater, not less, inequality in the world.

@willw5868 Год назад

I don’t think that’s true at all. Fitness is defined by an organism ability to reproduce. Do you think intelligent people are more likely to have more children? Doesn’t seem true to me. If anything it’s the opposite imo Evolution does not favor people who are more “successful” or happy, it favors those who reproduce more.

@casek6930 Год назад

@@willw5868 there is no doubt that there are unprecedented dysgenic trends taking place right now, but that doesn't change the fact that there are other pressures in operation that are redistributing power and wealth. We don't know how this will all end, but it seems that there are selective forces in play that are splitting populations into separate genepools.

@willw5868 Год назад

@@casek6930 yeah I would tend to agree with that. If you look at trends like online work and suburbanization, it seems that people are becoming more and more isolated within their social classes. My big concern would be gene editing. With how strict governments on banning it, I fear that only the ultra wealthy are going to have access to it when it be mes viable. Which would lead to a race of super enhanced beings who could limit access to genetic engineering to their own class, dividing humans strictly into normal and enhanced classes

@guitarazn90210 Год назад

@@willw5868 What would be the benefit of limiting gene editing? If you can create super enhanced beings after a few doctors appointments, the added value will be so high it would be insane not to democratize that tech. Many social problems could be solved.

@willw5868 Год назад

@@guitarazn90210 yes my point is that the current policy IS to ban or heavily restrict it. And when you effectively ban or heavily restrict something, only the powerful are going to have access it. So I agree with you in that gene editing should be widely available, but it doesn't look like that is going to be the case with current regulations

@AntonLauridsen Год назад

Going through the comments I'm astounded that nobody has mentioned fire and its consequences on culture, digestion and genes to support that new diet.

@maxravenwood3877 Год назад

4:43 made me very concious of the fact that I'm watching this while eating a pizza bagle with eggs and cheese

@phonyname5307 Год назад

One super interesting thing is the North Sea Population Replacement Hypothesis. Whereupon the economic upper 1/3 of the southeast english and low countries population outbred the lower 2/3 of the population three times over 800 years, completely replacing them. An amazing case of self-selection.

@flamencoprof Год назад

Not getting any hits for "North Sea Population Replacement Hypothesis". Sounds interesting. Got any hints for more info?

@ChocoboProduction Год назад

Would the invention of writing have triggered similar changes to accomodate for the different workload our brains needed to handle? And would different writing systems cause different adaptations? (Like the consumption of milk lead to lactose tolerance, but via different pathways?)

@H._sapiens Год назад

Writing actually reduces mental workload. Some of the earliest writing was for taking inventory. It requires more mental capacity to memorize large lists and perform mental calculations than writing it down.

@willw5868 Год назад

I really don’t think writing had that much of a survival impact for most of history. Average people only became literate in the last few hundred years. Until recently only people in certain specialization needed to read to survive, farmers, who were the large majority of the population, didn’t.

@schweglerd Год назад

Bravo on the Argentina pronunciation.

@hungrycolby Год назад

Drink cactus juice! It'll quench ya. Nothing is quenchier. It's the quenchiest! 😄

@SuperGalliam Год назад

DO THE MILK EPISODE!

@Astrapionte Год назад

Can we talk about Thylacosmilus?

@conradsieber7883 Год назад

Ben and Jerry's is adaptive evolution? Beautiful...

@marjanperveinis8355 Год назад

Sherpas are the people of the Himalayas mountains. A 2010 study identified more than 30 genetic factors that make Sherpas' bodies well-suited for high altitudes, including EPAS1, referred to as the "super-athlete gene" that regulates the body's production of hemoglobin, allowing for greater efficiency in the use of oxygen.

@ginnyjollykidd Год назад

Don't laugh at fruit flies! 👍 They reproduce quickly, they live 2 weeks, and they have 4, well-mapped-out, simple genes. This makes fruit flies easy to use for genetic studies. They are used all the time in university genetics classes. These are excellent subjects for study!

@moumous87 Год назад

Eating cooked soft food => losing wisdom teeth

@madkills10 Год назад

I thought cooking food would definitely be one

@Bass.sick.b1tch Год назад

Terrance McKenna is taking a victory lap in the great beyond lol

@wkrapek Год назад

I like you. And this is a good video. Thank you.

@alterego3734 Год назад

How about a video on evolution's multiple experiments with flight in theropods?

@d_camara 9 месяцев назад

It's very important for people to understand natural selection≠evolution, and that natural selection is one of many selection processes of evolution. People have this idea that evolution always takes millions of years to make any noticeable change, but they're thinking about mutation, and even then, it's not true for everything (fruit flies, viruses), and evolution could make big changes in a matter of generations if the genes for a good allele were already out there, like the classic example of white and black moths in the UK during industrialization; if a new selective pressure appears, and let's say, humans now benefit from being 50cm tall, and there were like a few dozen people that tall out there, in a few generations they'd be majority, a species can change DRASTICALLY in times that most people don't think are long enough for evolution to happen