How do you deal with high damage champions like Yone, Yi, Vayne, etc.? It doesn't seem to matter how much health or armour you put on, they still shred through you incredibly fast. Roots and Slows don't stop them from killing you or any nearby team mates so you really only have the Ult to stop them for a moment. And if they have lifesteal they're often healing from you rather than taking any damage and that makes life harder for the carries behind you as they're healing through the damage. Ignite and Thornmail help with countering the heal but it never seems to actually stop enough healing to change the result.
It's a bit tough tbh, I think it's harder to baron lane Nautilus then Alistar for sure but (in certain matchups) you can make it work, just play super passive and for the teamfights.