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please cross check where you explained the two ways an insurmountable antagonism can be formed. i think you interchange "antagonist" for agonist. you said the higher the affinity of the agonist instead of the higher affinity of the antagonist. please i need a feedback i'm a student and you are fantastic + remarkable and then excellent.
This is one of the best videos on lipid catabolism. I just love it... suffered a while before chancing upon this. Well-arranged from lipolysis to FA activation through to transport into mitochondrial matrix for B-oxidation.
thank you so much! you explained so much better and simpler than my textbook. this was exactly the pathway a exam-training question was wanting me to explain but my book went into waaay to many details for me to easily gain an overview. your video really helped create that overview!
Nice presentation, I have question about the degradation of glycogen using phosphoric acid. could you please explain if phosphoric acid can degrade glycogen.
Hi EKG science, could you consider doing a video on Positive Allosteric modulators (allosteric modulation in general) that goes as in depth as your your video on traditional agonists. I'd love to hear about concepts like cooperativity and affinity and efficacy from the stand point of drugs like these. Benzodiazepine's I believe are an example of a drug like this. I appreciate the videos, great work as usual.
It can cause significant drug interactions; therefore, therapeutic drug monitoring may be necessary to ensure optimal dosing and avoid any adverse effects or treatment failure.
Once a drug enters the body, the process of elimination begins (hepatic, biliary, and urinary). Elimination involves both metabolism and excretion. When considering the sequence of events leading up to the removal of the drug from the body, phase 2 metabolism usually occurs before then. It involves conjugation reactions that make the drug or phase 1 metabolites more suitable for excretion. However, if the metabolites from phase 1 are sufficiently polar, they can be excreted by the kidneys. Many phase 1 metabolites are still too lipophilic so phase 2 occurs. I hope that helps!
