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Carlo Carandang
Carlo Carandang
Carlo Carandang
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This channel is about all things data science, psychiatry and mental health. Carlo Carandang, MSc, the Data Scientist, focuses on Enterprise Data Science for large organizations. Carlo Carandang, MD, the Doctor, is also a psychiatrist and anxiety/depression expert. Dr. Carlo is the founder of AnxietyBoss.com (Anxiety Online Self-Help), author of Anxiety Protocol (Anxiety Self-Help Book), and formulator of KalmPro (Anxiety Natural Supplement). If you have a question that you want answered, please contact me at the email below, and I will post the question and answer in future videos on this RU-vid Channel.

Milestones:
200 subscribers- April 7, 2017
50,000 views- August 11, 2017
300 subscribers- September 2, 2017
400 subscribers- December 10, 2017
500 subscribers- March 23, 2018
2000 subscribers- December 2022
Tennis in Cuba, March 2023
1:26
Год назад
How to Rig a Topper - Part 1
5:47
3 года назад
Let’s Cook with Carlo- BBQ Ribs
4:12
3 года назад
MyRealtor demo5
3:24
3 года назад
MyRealtor demo4
1:25
3 года назад
MyRealtor demo3
10:26
3 года назад
MyRealtor demo2
10:40
3 года назад
MyRealtor demo1
2:21
3 года назад
Clink
0:29
4 года назад
Deep Fried Ice Cream
2:09
4 года назад
Book Ur Doctor App
25:14
6 лет назад
Dr. Carlo YouTube Channel Trailer
1:13
7 лет назад
Can stress cause acne?
3:13
8 лет назад
Комментарии
@Complexanxiety
@Complexanxiety Год назад
My social anxiety makes me vomit, is propranolol any good to manage this? My doctor prescribed me Venlafaxine and the Viibryd but they increased my anxiety like crazy and made me have suicidal thoughts; along with excessive sweating and I was only sleeping two hours a night for almost three years straight. Also, are SNRIs and SSRIs bad for me if I have high blood pressure? Thanks!
@vimcola9961
@vimcola9961 Год назад
I tried desvenlafaxine and it didn't help. My psychiatrist said I most likely didn't have serotonin deficiency because desvenlafaxine would help 90% of it and that no antidepressants would help me. But because I wanted to try again, he prescribed me another antidepressant. He's also not sure if there are any medications that can help me, and that's often the case with social anxiety because it often has other causes. He thinks I should do therapy or inpatient treatment with medication. I will also see another psychiatrist soon, but he is also very experienced.
@ottolandin
@ottolandin Год назад
I may be crazy but it seems that my Cymbalta helps prevent certain hallucinations while also stopping anxiety.
@vanjabursh6642
@vanjabursh6642 Год назад
Hi i' m using 150 mg Venlafaxine from 2006 and 3 x 0.5 mg but my anxiety is getting worse i m also very hyperactive is escitolapram a food alternative and how do you switch?
@philn5703
@philn5703 Год назад
My experience with these meds was horrible. Increased anxiety, compulsive shopping (I normally hate shopping), sexual dysfunction, insomnia, nausea, increased abnormal negative ideation, etc. Benzodiazepines have been much more effective. I don't like the long-term use dependence, but it helps a lot.
@md.mostakim2570
@md.mostakim2570 Год назад
Sir for bipolar depression I have taken sertraline, fluxetine, lithium carbonate. But no benefit. Valproic acid made me little better. But clonazepam make me cured and best. Can i take it for years?
@samp739
@samp739 Год назад
I siffer from both severe deprrssion / anxiety. Sertraline 200 for 3 month ni affect. Duno what to try next
@PauloRLustosa
@PauloRLustosa Год назад
Boa tarde. Gostei muito da explicação. Obrigado. Vou assistir mais dos seus vídeos.
@CarloCarandang
@CarloCarandang Год назад
Thanks for visiting!
@annstar2793
@annstar2793 Год назад
Is that dangerous though to take a benzo and GABA?
@CarloCarandang
@CarloCarandang Год назад
Take one, or the other
@xyzspyder
@xyzspyder Год назад
His voice did not match my first thought before clicking
@CarloCarandang
@CarloCarandang Год назад
Thanks? 😂
@Noob-oc1wp
@Noob-oc1wp Год назад
thanks
@CarloCarandang
@CarloCarandang Год назад
You’re welcome
@A444-h7x
@A444-h7x Год назад
Sir how to stop negetiv thouth
@CarloCarandang
@CarloCarandang Год назад
This may be helpful anxietyboss.com/how-anxiety-evolves-the-negative-cycle-of-anxiety/
@wunderedich5101
@wunderedich5101 Год назад
Thank you very much, great visualization and explanation! Your style of narration is somehow calming - no GABA supplements necessary anymore ;D
@CarloCarandang
@CarloCarandang Год назад
Thanks for your feedback!
@92foxcarguy21
@92foxcarguy21 Год назад
Why would you take SNRI's the use a beta blocker to counter the adrenaline? Why not just go to the SSRI and allow the norepinephrine to be reabsorbed?
@CarloCarandang
@CarloCarandang Год назад
Yes- this is the way
@alqadeeb
@alqadeeb Год назад
Just take ssri and you will be okay
@CarloCarandang
@CarloCarandang Год назад
Yes
@matthewlindsay1372
@matthewlindsay1372 Год назад
In treating GAD, what if the common SSRI's make you apathetic? In that scenario, would an SNRI be a better choice than an SSRI to treat GAD? Or is there an SSRI that doesn't cause as much apathy?
@CarloCarandang
@CarloCarandang Год назад
Both SSRIs and SNRIs can make you apathetic. In fact, part of the reason they work for treating anxiety and depression is that they make you care less about the things that you worry/ruminate about.
@tlghan
@tlghan Год назад
For ibs d and intense anxiety, my doctor recommended 60 mg duloxetine, but I'm afraid to use it. Duloxetine is said to be effective for ibs d. Is Duloxetine helpful for intense anxiety? In order to start the drug, the doctor prescribed xanax and advised me to use it for 1 month, will addiction develop?
@CarloCarandang
@CarloCarandang Год назад
Duloxetine can be helpful for your anxiety, and with proper medical supervision, you should not become addicted to Xanax.
@swativyas7962
@swativyas7962 Год назад
What is difference between SSRI & SNRI if both works in same way ? What is need to block reputable of Nor apprirefrine?only SSRI is not sufficient?
@CarloCarandang
@CarloCarandang Год назад
SSRI (Selective Serotonin Reuptake Inhibitors) and SNRI (Serotonin-Norepinephrine Reuptake Inhibitors) are two types of antidepressant medications that work by increasing the levels of certain neurotransmitters in the brain. SSRIs primarily target the neurotransmitter serotonin, which is associated with mood regulation, while SNRIs target both serotonin and norepinephrine, which is involved in the body's "fight or flight" response. The main difference between SSRIs and SNRIs is the neurotransmitters they target, which can affect their effectiveness and potential side effects. While both medications can be effective in treating depression, anxiety, and other mental health conditions, some people may respond better to one type of medication over the other. As for the question about blocking the reuptake of norepinephrine, it is necessary in some cases because norepinephrine is involved in regulating arousal, attention, and mood. By preventing the reuptake of norepinephrine, SNRIs can increase the amount of the neurotransmitter available in the brain, which can have a positive effect on mood and energy levels. In some cases, an SSRI alone may not be sufficient in treating a person's symptoms, and a SNRI or another type of medication may be added to their treatment plan. But as this video has detailed, norepinephrine side effects from SNRIs may not be tolerable and beneficial when treating anxiety disorders.
@swativyas7962
@swativyas7962 Год назад
@@CarloCarandang Thankyou so much Sir foryour detaied & informative reply 🙏😊
@swativyas7962
@swativyas7962 Год назад
@@CarloCarandang what are side effects of Noraspirefrine & if it’s over dose it’s harmful to patient?
@swativyas7962
@swativyas7962 Год назад
Why SNRI is also use to increase seretonin in synaps
@CarloCarandang
@CarloCarandang Год назад
That's what it does. Please view the video in detail- I explained it clearly in the video.
@thedaydreamer7972
@thedaydreamer7972 Год назад
HI, good videos you have here,,,I have been an athlete my whole life and the last 5 years I have been using benzos, like xanax and klnopin lows doses each day to deal with anxiety,,,,,I have since stopped benzos,,,,but what I am left with is horrible squeezing in my face, neck, teeth, abdomen, awful muscle tension, off balance in my whole body,,,,I seen the top doctors and neurologists and they have found nothing,,,CTs and MRIs of brain and stomach as well,,,,I know you cant really measure brain chemisty accuratly, but I did take a urinary neurotransmitter panel test and it seems I am really low in dopamine, norepinephrine, PEA and GABA,,,,,My biggest symtoms present in my body with horrid squeezing and tension and agitation,,,,,,I have been looking at amitriptiline to give it a try, whats you opinion about this? DO you think amitriptiline is a worth while drug? I am in my late 40s ,,,ty for your time
@CarloCarandang
@CarloCarandang Год назад
I'm sorry to hear about the symptoms you've been experiencing. Benzodiazepine withdrawal can be difficult and may cause long-lasting symptoms such as muscle tension, agitation, and balance issues, as you've described. It's good to hear that you've consulted with doctors and neurologists, and have had imaging studies done to rule out any underlying medical conditions. Regarding your question about amitriptyline, it is a tricyclic antidepressant that is commonly used to treat depression, anxiety disorders, and chronic pain. It works by increasing the levels of certain neurotransmitters, including serotonin and norepinephrine, in the brain. While amitriptyline may be effective for some people with anxiety and tension-related symptoms, it's important to note that it can also cause side effects such as dry mouth, constipation, dizziness, and drowsiness. Additionally, it may interact with other medications or medical conditions you may have, so it's important to discuss with your doctor if it's a suitable option for you. It's also important to note that there are other non-pharmacological approaches that may help with anxiety and muscle tension, such as cognitive-behavioral therapy, relaxation techniques, and exercise. It may be worth discussing these options with your doctor or a mental health professional as well. Ultimately, the decision to try amitriptyline or any other medication should be made in consultation with your doctor, who can evaluate your individual situation and recommend the most appropriate treatment approach for you.
@swativyas7962
@swativyas7962 Год назад
In Dippression both SSRI& SSRI are used? Why?what is work of SNRI in Dippression? Too much SSRI in Macydulla is harmful to Macydulla?
@CarloCarandang
@CarloCarandang Год назад
amygdala?
@swativyas7962
@swativyas7962 Год назад
@@CarloCarandang yes
@swativyas7962
@swativyas7962 Год назад
How much take time for effect on maycdulla? It’s work is same way on Dippression?
@CarloCarandang
@CarloCarandang Год назад
amygdala?
@swativyas7962
@swativyas7962 Год назад
If Macdulla get more SSRI & SSRI it’s make adverse effect?& make Dippression worsen?
@CarloCarandang
@CarloCarandang Год назад
amygdala?
@swativyas7962
@swativyas7962 Год назад
How serotonin syndrome uccer
@CarloCarandang
@CarloCarandang Год назад
can you repeat your question
@jdt8983
@jdt8983 Год назад
When people talk about blunting - is that perception more prominent in the initial phase of treatment (as the drug is trying to create a new homeostasis?)
@CarloCarandang
@CarloCarandang Год назад
SSRI (selective serotonin reuptake inhibitor) and SNRI (serotonin-norepinephrine reuptake inhibitor) medications can cause a side effect commonly known as emotional blunting, which is a reduction in the intensity of emotions. This side effect is generally more prominent during the initial phase of treatment and can become less noticeable over time as the brain adjusts to the medication's effects. During the first few weeks of treatment with these medications, the brain is adjusting to the new levels of serotonin and norepinephrine neurotransmitters. This process can cause changes in the way the brain processes emotions, which may result in emotional blunting. However, as the brain adapts to the medication, this side effect may become less noticeable, and the individual may begin to experience emotions more fully again. It's important to note that not everyone experiences emotional blunting as a side effect of SSRI and SNRI medications, and the intensity and duration of the effect can vary from person to person. Additionally, emotional blunting may also be a symptom of depression or other mental health conditions, so it's essential to discuss any changes in emotional experience with a healthcare provider to determine the best course of treatment.
@jdt8983
@jdt8983 Год назад
@@CarloCarandang thank you for the thorough response
@agentblue52
@agentblue52 Год назад
Hi Doc, In what situations are SNRI's prescribed? Isnt it old SSRI's like the first one - fluoxitine have a better track record in treating depression and anxiety. The big problem here in the Phils is there are no lower doses like 5mg and 10mg of Fluoxitine to start low. Initially i had to mix the 20mg powder in liquid and measure with a liquid measuring cup to get an estimate 5mg to start on a low dose. 20mg is too strong for me for a start, i believe docs here always give out a benzo 2-3x a day to go with that on the first month. Geez. It is effective but very strong to start on standard 20mg dose. Can other patients.take 20mg at the start without any benzo? Years ago i was also prescribed Pristiq and did little to help my depression. Same.side.effects like restlessness/anxiety but it did not treat the.depression well even after 5months. Fluoxitine ia effective but have to start on a low dose for some people...
@CarloCarandang
@CarloCarandang Год назад
SNRIs (Serotonin and Norepinephrine Reuptake Inhibitors) are prescribed for the treatment of depression and anxiety disorders. SNRIs work by increasing the levels of two neurotransmitters, serotonin and norepinephrine, in the brain. This is different from SSRIs (Selective Serotonin Reuptake Inhibitors), which only target serotonin. SNRIs may be prescribed when SSRIs have not been effective, or if the patient has both depression and anxiety. Both SSRIs and SNRIs have been found to be effective in treating depression and anxiety disorders, but the choice of medication depends on individual patient needs and preferences, as well as the severity of the condition. In some cases, a combination of medication and psychotherapy may be recommended. Starting at a low dose and gradually increasing it is often recommended to minimize side effects and ensure that the medication is well-tolerated. However, it is important to follow the prescribing physician's advice and not adjust the dose or medication without consulting with them first. In some cases, additional medication may be prescribed to manage side effects or to provide short-term relief while waiting for the antidepressant to take effect. However, benzodiazepines should be used with caution due to their potential for addiction and other side effects. If you have concerns about your medication or dosage, it is important to discuss them with your prescribing physician. They can provide guidance and support in finding the most effective treatment for your individual needs.
@swativyas7962
@swativyas7962 Год назад
Is SNRI used in Dippression?
@CarloCarandang
@CarloCarandang Год назад
Yes, SNRI (Serotonin-Norepinephrine Reuptake Inhibitor) medications are commonly used in the treatment of depression. SNRIs work by increasing the levels of two neurotransmitters, serotonin and norepinephrine, in the brain, which can help regulate mood and alleviate symptoms of depression. Some examples of SNRI medications include venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq). It's important to note that any medication should be prescribed by a licensed healthcare professional and used as directed.
@agentblue52
@agentblue52 Год назад
Hi Kababayan Doc. For some people who have been prescribed FLUOXITINE 20mg years ago (for situational depression/loss of a loved one), just EVERY OTHER DAY day years ago... Will taking 10mg every day now have the same effect? I am currently on 10mg after being on 5mg for three weeks. Sensitive to medications ever since, even half tablet loratidine which many says is not causing sleepiness, makes me really sleepy. New doctor will see me again after 10 days if 10mg is sufficient. I know 20mg Fluox is the "standard" dosage for depression (triggered by terminal cancer family member) , but i had bad side effects experience from starting Fluoxitine. I THINK ALL PEOPLE DO while starting SSRI's. Escitalopram also makes me restless (even after starting at low dose) and ringing of ears started when dose was titrated from 1/4 tab to 1/2 then to 1 whole tab when all side effects breaks lose. Had to stop this. Staying on Fluoxitine as it worked years and decades ago.
@CarloCarandang
@CarloCarandang Год назад
It's important to discuss any changes in medication dosages with your doctor to ensure that you are receiving the proper treatment for your condition. In your case, it may be possible that taking 10mg of fluoxetine every day can have the same effect as taking 20mg every other day, but this would depend on several factors such as the severity of your depression, your response to the medication, and any potential side effects. It's also possible that your sensitivity to medications could make it difficult to find an effective dose without experiencing side effects. It's important to let your doctor know about any past experiences with medications and any current side effects you are experiencing. Your doctor may choose to continue with the current dose of 10mg and monitor your symptoms, or they may decide to increase the dosage if necessary. They may also consider alternative medications if fluoxetine is not effective or causes too many side effects. It's important to remember that starting SSRI medications can cause side effects, but these often improve over time. If you have any concerns or questions about your medication, don't hesitate to speak with your doctor.
@agentblue52
@agentblue52 Год назад
@@CarloCarandang thanks for the reply doc. Ok i will let the doctor (a neuro psych) monitor my symptoms. There is always a long line every consultation, i guess this illness is rampant nowadays. Going from 5mg to 10mg seems easier than straight to 20mg. I think the buspirone 5mg twice a day helps minimize the side effects initially. Also prescribed very small dose of Alprazolam (again) for sleep as i think Fluoxitine may cause some sleeplessness. Just took very small piece during initial days of 5mg Fluoxitine. Side effects seems to fade after 3 weeks. I had to chew gum almost half of the day during the initial weeks. Now i just take loratidine for uninterrupted sleep every up dose of Fluoxitine. Hoping to get better soon. Thanks Doc
@CarloCarandang
@CarloCarandang Год назад
good luck to you
@usman2131
@usman2131 Год назад
Ssri work... helped me a lot.
@CarloCarandang
@CarloCarandang Год назад
Glad to hear it!
@agentblue52
@agentblue52 Год назад
How about Buspirone. How does it work for anxeity and depression?
@CarloCarandang
@CarloCarandang Год назад
Buspirone works for Generalized Anxiety Disorder, but is not prescribed for depression.
@agentblue52
@agentblue52 Год назад
@@CarloCarandang ok. Thanls for reply Doc Carlo. I am now taking 5mg Buspirone twice a day plus Fluoxitine 10mg (Initial side effects of Fluox are very hard. 3rd week now, side efx slowly diminishing). Hope this works soon
@CarloCarandang
@CarloCarandang Год назад
good luck to you
@tonyztiger75
@tonyztiger75 Год назад
Thanks for sharing your knowledge 🙏 love your website 😊 👍
@CarloCarandang
@CarloCarandang Год назад
Glad you enjoy it!
@sc9683
@sc9683 Год назад
Hi Dr ❤ You seem so lovely. I wish you were in Australia to help me 😢 I have just started Straterra (5 days ago) for ADHD. I already feel like I am sleeping better (which I didn’t expect, I was sure it would make mg insmonia worse). But I have awful constipation. I don’t know if I should stick with it, and this is a side effect that will likely pass or if it is most likely a permant side effect? Can you please advice me your thoughts? I cannot afford to see. specialist here to help support me with this 🙏🏻
@CarloCarandang
@CarloCarandang Год назад
Hi! thanks for the positive feedback. Constipation is a common side effect of Strattera (atomoxetine) and can occur in up to 15% of patients who take it. It is possible that this side effect may improve over time as your body adjusts to the medication, but it's difficult to predict whether it will be a permanent side effect for you. In general, if you experience any side effects from a medication that are concerning or disruptive to your daily life, it's important to speak with your doctor. They may be able to recommend ways to manage the side effects or suggest an alternative medication. If you are unable to see a specialist, you may want to consider talking to your primary care physician or pharmacist. They may be able to suggest over-the-counter remedies or make changes to your diet or lifestyle that could help alleviate your constipation. In the meantime, make sure you are drinking plenty of water and eating a high-fiber diet. Regular exercise can also help improve bowel movements. Avoiding certain foods that can worsen constipation, such as dairy and processed foods, may also be helpful. Ultimately, it's up to you to decide whether you want to continue taking Strattera. However, it's important to weigh the potential benefits of the medication against the side effects you are experiencing. If you decide to continue taking it, be sure to monitor your symptoms and discuss any concerns with your doctor.
@sc9683
@sc9683 Год назад
@@CarloCarandang You are so lovely to reply! Please I have one more question: The side effect actually DID go away! I am having very positive effects from Straterra. BUT since I started in a month ago I have broken out in ACNE which I have never had before in my life. If it possibly connected or a huge coincidence? Have you evey heard of this before with SNRI meds?
@CarloCarandang
@CarloCarandang Год назад
I'm glad to hear that the side effect you were experiencing went away and that you are now experiencing positive effects from Strattera. In regards to your question, while acne is not a commonly reported side effect of Strattera (atomoxetine), it is possible that it could be related to the medication. Strattera is a norepinephrine reuptake inhibitor (NRI) used to treat attention deficit hyperactivity disorder (ADHD). Although it is not classified as a selective serotonin-norepinephrine reuptake inhibitor (SNRI), it does have some similarities to medications in that class. Acne can be a side effect of some medications, including some SNRIs. However, it is not a commonly reported side effect of Strattera. If you are concerned that your acne may be related to Strattera, it may be worth discussing with your healthcare provider to determine if there may be other underlying causes or if a medication change may be necessary. It's important to note that everyone's experience with medication can be different and some individuals may have unique side effects. If you have any concerns or questions about the side effects you are experiencing, it's always best to consult with your healthcare provider.
@MoDogg143
@MoDogg143 Год назад
Thoughts on l-tryptophan or l-theanine over GABA?
@CarloCarandang
@CarloCarandang Год назад
L-tryptophan and L-theanine are both amino acids that have been shown to have calming and mood-boosting effects. GABA, on the other hand, is a neurotransmitter that helps to reduce neuronal excitability, and is often used as a supplement to promote relaxation and reduce anxiety. While all three of these supplements may have some similar effects, there are some differences between them. L-tryptophan is a precursor to serotonin, a neurotransmitter that regulates mood, sleep, and appetite. L-theanine, on the other hand, is an amino acid found in green tea that has been shown to promote relaxation and reduce stress. GABA is a neurotransmitter that is synthesized from glutamate, and is known for its calming and anti-anxiety effects. However, some studies have suggested that GABA supplements may not be effective at crossing the blood-brain barrier and increasing GABA levels in the brain. Overall, the choice between L-tryptophan, L-theanine, and GABA may depend on the individual's specific needs and preferences. It is always important to talk to a healthcare provider before taking any new supplements, as they may interact with medications or have other side effects. And you don't have to take them separately- try a supplement which contains these and other anxiety supplements in one product: KalmPro.com
@8888ultima
@8888ultima Год назад
Hi doctor, I have bad general anxiety disorder, overthinking, worrying, panic attack and agoraphobia. Tried ssri Prozac and le apron not working for well. Doctor ask to me try Desvenlafaxine (Pristiq) do you think it will work well for me?
@8888ultima
@8888ultima Год назад
If not what are your recommendations and starting dosage?
@CarloCarandang
@CarloCarandang Год назад
It is important to consult with your doctor or a licensed healthcare professional who is familiar with your medical history and can provide you with personalized recommendations. Desvenlafaxine (Pristiq) is an antidepressant medication that belongs to a class of drugs known as serotonin-norepinephrine reuptake inhibitors (SNRIs). It works by increasing the levels of serotonin and norepinephrine in the brain, which can improve mood and reduce anxiety symptoms. The starting dosage of Desvenlafaxine (Pristiq) will depend on various factors, including your age, weight, medical history, and current medication regimen. It is important to follow your doctor's instructions and dosing recommendations carefully to avoid any potential side effects or complications. In addition to medication, it is also recommended to seek therapy and engage in self-care practices, such as mindfulness, exercise, and stress reduction techniques, to help manage anxiety and improve overall well-being.
@lilypoppy1962
@lilypoppy1962 Год назад
Is Wellbutrin going to make my panic attacks worse? Or is it going to help. I’m terrified to try it.
@CarloCarandang
@CarloCarandang Год назад
It can make it worse.
@thomasmueller2319
@thomasmueller2319 Год назад
Beta blockers fixed my problems. After the pandemic and a breakup from my gf i developed anxiety , mostly physical, beta blockers saved me, no more anxiety.
@CarloCarandang
@CarloCarandang Год назад
I'm glad to hear that you found relief for your anxiety symptoms through beta blockers. It's important to remember, however, that beta blockers are typically used to treat physical symptoms of anxiety such as a rapid heartbeat or sweating, and do not address the underlying psychological causes of anxiety. If you're still struggling with anxiety, it may be helpful to speak with a mental health professional who can help you develop strategies for managing it more effectively. Therapy and counseling can be very beneficial in reducing anxiety symptoms and improving overall mental health.
@letsgofishingene
@letsgofishingene Год назад
I literally took off running once. Why the extreme calm after one of these? Clarity of thought too.
@CarloCarandang
@CarloCarandang Год назад
Not sure- not much information given
@opencurtin
@opencurtin Год назад
I get heart palpitations from SSRIs would SRNIs be better ?
@CarloCarandang
@CarloCarandang Год назад
Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are both types of antidepressant medications. While they work in similar ways, they target different neurotransmitters, and some people may experience different side effects with one class of drugs compared to the other. If you are experiencing heart palpitations as a side effect of SSRIs, switching to SNRIs may or may not alleviate this symptom. It's possible that you may experience different side effects with SNRIs, and some people may still experience heart palpitations with this class of drugs. If you're experiencing heart palpitations with your SSRI, I would recommend that you speak with your doctor. They may be able to adjust your dose, switch you to a different medication, or explore other treatment options. Keep in mind that it's important to never stop taking a medication without first speaking to your doctor, as suddenly stopping an antidepressant can cause withdrawal symptoms and make your symptoms worse.
@bpggg
@bpggg Год назад
So let me get this straight. Since increasing NE transmission is anxiogenic why would you want to work at cross-purposes with 5HT inhibitory effects? Do lower doses effect NE less? Is there advantage in increasing NE for anxiety in the long term? I understand NET helps increase DA and NE in the prefrontal cortex. Does the PFC itself have inhibitory properties upon the fear circuitry. I know NET on it's own helps in ADHD I understand in the PFC? Do you think it's just being marketed as such for obvious reasons (i.e. $$$) ? Wild thought I had is perhaps enhancing someone's sense of agency (essentially a little pep in their step) maybe itself can decrease anxiety by feeling more engaged in being to address issue in life that are anxiogenic. This is just one my speculations. I'd appreciate your thoughts on the matter. Thank you.
@CarloCarandang
@CarloCarandang Год назад
The neurotransmitter systems in the brain are complex and interrelated, and modulating one can have effects on others. The noradrenergic system (NE) is involved in the regulation of mood, arousal, and attention, and its activity has been implicated in anxiety disorders. While NE transmission can have anxiogenic effects, in some cases increasing NE transmission in the prefrontal cortex (PFC) can have beneficial effects on anxiety. Low doses of norepinephrine reuptake inhibitors (NRIs) can have different effects than high doses, and the optimal dose can vary depending on the individual and their specific symptoms. Some studies have suggested that increasing NE transmission in the PFC can have long-term benefits for anxiety, as it can enhance executive control and decision making, which can be impaired in anxiety disorders. The PFC is thought to have inhibitory effects on the fear circuitry in the brain, as it is involved in regulation of emotion and stress response. Some studies have shown that increasing NE transmission in the PFC can enhance PFC-mediated inhibition of the amygdala, which is involved in processing fear and anxiety. As for the use of NRIs in ADHD, there is evidence to suggest that increasing NE transmission in the PFC can have benefits for attention and executive function in individuals with ADHD. However, it is important to note that the use of NRIs for ADHD is still a topic of ongoing research and discussion in the scientific and medical communities. Finally, enhancing someone's sense of agency and providing a "pep in their step" could indeed have potential benefits for decreasing anxiety by helping the individual feel more empowered and engaged in addressing their anxiogenic issues. However, more research is needed to understand the specific mechanisms by which this occurs and whether this approach is effective for all individuals with anxiety. In conclusion, the role of NE and NRIs in the regulation of anxiety and ADHD is complex and still not fully understood. While some studies have suggested potential benefits, it is important to approach these treatments with caution and under the guidance of a healthcare professional.
@emmatreloar7917
@emmatreloar7917 Год назад
What would you recommend If SSRI's have too many side effects and make depression/suicidal thoughts worse, SNRI's have same effect, benzodiazepines don't help with anxiety just make you sedated and lead to tolerance, tricyclics cause too many side effects. For anxiety, what other options are there? For someone with low BP, could they try beta blocker?
@CarloCarandang
@CarloCarandang Год назад
If you have tried several medications for anxiety and depression, and have experienced side effects or worsening of symptoms, it's best to consult with a mental health professional for further evaluation and personalized treatment recommendations. They may suggest alternative treatments such as therapy, lifestyle changes, or alternative medications that might work better for you. In regards to beta blockers, they are often used to treat high blood pressure, heart conditions, and performance anxiety. However, beta blockers can lower blood pressure, so they may not be a suitable option for someone with low blood pressure. Alternative options that a mental health professional may consider include anticonvulsants, anti-anxiety medication, or atypical antipsychotics, however, these options should be discussed with a healthcare professional before taking them, to ensure they are appropriate and safe for you. It's important to keep in mind that finding the right treatment for anxiety and depression can take time and may involve trying several options before finding the one that works best for you. It's also important to address any physical or mental health conditions that may be contributing to your symptoms and to follow a healthy lifestyle.
@JimmyStruthers1000
@JimmyStruthers1000 Год назад
Thank you sir for your video! Very informative!
@CarloCarandang
@CarloCarandang Год назад
Glad it was helpful!
@hoyconjessi5141
@hoyconjessi5141 Год назад
Hi Dr, I been prescribed Cymbalta 30mg in the morning for anxiety and panic attacks. I also have trouble sleeping so prior to this prescription I been on 1mg of klonopin and 150mg of trazodone. I am yet to start the Cymbalta tomorrow but I’m worried about drug interactions. My Dr. said there will be no issues but I don’t know if maybe I should just try the Cymbalta and klonopin. Hope you can help! Thank you
@CarloCarandang
@CarloCarandang Год назад
It's always important to be cautious about potential drug interactions, especially when taking multiple medications. It's great that you're reaching out to seek more information! Cymbalta (duloxetine) and Klonopin (clonazepam) are both commonly used to treat anxiety and panic disorders. Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant, while clonazepam is a benzodiazepine. In general, combining an SNRI with a benzodiazepine can increase the risk of side effects such as drowsiness, confusion, and increased risk of falls, especially in older adults. Additionally, taking benzodiazepines with an antidepressant can increase the risk of overdose, as they can both cause sedation and affect breathing. It is important to talk to your healthcare provider about any concerns you have regarding the combination of these medications. Your doctor is the best person to advise you on this, as they are familiar with your medical history and other factors that may impact your treatment. They may adjust your dosages, switch to a different medication, or suggest other treatments. If you have trouble sleeping, it's also worth discussing this with your doctor, as some antidepressants can cause insomnia, while others can help with it. In conclusion, it's always best to err on the side of caution when taking multiple medications, and to consult with a healthcare professional for personalized advice.
@nicoc7024
@nicoc7024 Год назад
Is nortryptilline basically an snri too? I know it’s technically a tca but it has more effects on norepinephrine correct?
@CarloCarandang
@CarloCarandang Год назад
Nortriptyline is a tricyclic antidepressant (TCA) that is sometimes classified as a norepinephrine reuptake inhibitor (NRI) because it has the ability to inhibit the reuptake of norepinephrine by neurons in the brain. However, it is generally not considered to be a selective norepinephrine reuptake inhibitor (SNRI), as it also has significant effects on serotonin and other neurotransmitters. TCAs are a class of antidepressant medications that were developed in the 1950s and are still used today to treat depression and other mental health conditions. They work by inhibiting the reuptake of serotonin and norepinephrine by neurons in the brain, which leads to an increase in the concentration of these neurotransmitters in the synapses between neurons. This can help improve mood and alleviate the symptoms of depression. Nortriptyline is one of several TCAs that are commonly used to treat depression. It's important to note that nortriptyline is not an SNRI, and it is not classified as a selective serotonin reuptake inhibitor (SSRI) either. It is a TCA that has some effects on norepinephrine and serotonin, but it also has other effects on other neurotransmitters and is not as selective as an SNRI or SSRI. It is important to discuss the specific effects and potential risks of any medication with a healthcare provider before starting treatment.
@nicoc7024
@nicoc7024 Год назад
@@CarloCarandang I was prescribed for migraine low dose 25mg do you think that would be enough to cause vasoconstriction to the point of possibly causing clots?
@CarloCarandang
@CarloCarandang Год назад
Nortriptyline is a tricyclic antidepressant that is sometimes used to prevent migraines. It is not known to cause vasoconstriction, or narrowing of the blood vessels, as a side effect. In fact, tricyclic antidepressants like nortriptyline may actually have the opposite effect, causing blood vessels to dilate. However, it is important to note that all medications have the potential to cause side effects, and it is always a good idea to talk to your doctor if you have any concerns about your medication. If you are experiencing any unusual symptoms or side effects while taking nortriptyline, it is important to report these to your doctor as soon as possible.
@nicoc7024
@nicoc7024 Год назад
@@CarloCarandang ok I thought norepinephrine caused vasoconstriction?
@nicoc7024
@nicoc7024 Год назад
??
@empireravenshadow5
@empireravenshadow5 Год назад
Doc, u seem like you could use a little xanax urself
@CarloCarandang
@CarloCarandang Год назад
Takes one to know one lol
@אופירגילת
@אופירגילת Год назад
So what is the a class of snri drugs for? What is the benefit of norepeniphrin ? The norepinephrin isn't there as a byproduct
@CarloCarandang
@CarloCarandang Год назад
It's indicated for depression.
@Abdallah-ph3ef
@Abdallah-ph3ef Год назад
Does passion flower work as xanax?
@CarloCarandang
@CarloCarandang Год назад
Xanax is for fast relief. Passion flower works, but you need to take it for a few weeks for it to work. Passion flower is a key ingredient in KalmPro: www.kalmpro.com/
@Abdallah-ph3ef
@Abdallah-ph3ef Год назад
@@CarloCarandang what about effectiveness? Is it effective after a few weeks in treating anxiety? Thanks for your response 👍
@CarloCarandang
@CarloCarandang Год назад
It can take up to a couple of months to see full effect.
@BalkanDeputy
@BalkanDeputy Год назад
I took one of those at the advice of my ENT. In 2 hours my Vertigo was 80% gone after having The vestibular migraine for 9 months. At 2am the next morning I woke up with a blinding headache. I took my BP and it was 196/121. Yeah off to the ER I went. If I have to decide between Vertigo and a Stroke,,,,Easy choice.
@CarloCarandang
@CarloCarandang Год назад
Indeed- easy choice
@kevinmays5308
@kevinmays5308 Год назад
Why do I shake uncontrollably when my fight or flight kicks in... I wasn't always this way
@CarloCarandang
@CarloCarandang Год назад
anxietyboss.com/panic-attacks-neural-biochemical-response/
@brandismassey3678
@brandismassey3678 Год назад
So, Wellbutrin would be a no go for a person with depression, anxiety, and racing thoughts. My doctor just prescribed and I’ve been scared to take…
@CarloCarandang
@CarloCarandang Год назад
Good for depression, not for anxiety
@meridenpontiff4437
@meridenpontiff4437 Год назад
What happens if you’ve tried pretty much every medication for anxiety and nothing is helping. /:
@CarloCarandang
@CarloCarandang Год назад
www.kalmpro.com/