Presented by Todd Coleman, PhD, Associate Professor of Bioengineering at Stanford University. Moderated by Bryan Smith, PhD.
We will highlight recent technological and methodological advances in deploying miniaturized technologies that can monitor the electrophysiologic patterns of the visceral nervous system. Specifically, we will showcase recent developments in biomedical signal processing that enable non-invasive tracking of the slow wave patterns associated with the stomach. We will also describe recent developments of thin, stretchable, wireless biosensor patches that can be embedded within routinely used medical adhesives for ambulatory recording of these gastric electrophysiologic patterns. We will illustrate how such systems can also be used in tandem with novel miniaturized pacing devices to enable closed-loop neuromodulation of the enteric nervous system. We will also briefly discuss ongoing efforts in exploring the electrophysiologic basis of the gut-brain axis with concurrent electrophysiologic recordings of the brain and stomach. We will conclude with a summary of the knowns and unknowns in how multi-organ physiology research, technology miniaturization, and data science may create unique opportunities for the intersection of engineering, applied probability, neuroscience, and medicine.
9 сен 2024
