Might wanna give the Staball Match a try if you got any. It did pretty decent velocity wise in the 22 Creedmoor. Better than I could get with 6.5 which I was hoping for since their both not cheap but better priced than other powders.
Those FailSafe bullets are the bees knees on large game, buuuttt....discontinued 😢. Don't waste them on paper, other than zeroing. Once dialed in, compare poi with a cheap, common load and then use IT for zeroing in future years. 4166 is one of thee greatest powders for 22-250 to come down the pike in many years. I haven't tried Staball 6.5 in it yet.