Acute Myeloid Leukemia | Clinical Presentation 

My son was diagnosed with AML three years ago when he was 19. He had acute monocytic leukemia. Interestingly, while he had probably had it for a little while, it was diagnosed after he had his wisdom teeth removed, and it didn't seem to be healing and his gums were extremely swollen. That, along with his WBC count of 108,000 led his oncologist to diagnose him even before he had any testing done. He also had it in his cerebral spinal fluid. He went through 5 rounds of intense chemotherapy. He has been in remission for 3 years, and is engaged to get married this summer.

I'm a medical student. I've never seen any lecture better than this. Thank you very much.

I got diagnosed with acute myeloid leukaemia aged 14, after 3 months of symptoms and been told by doctors it was a water infection, pulled muscles and puberty. Finally one doctor listened and ordered blood tests. 18 months later from remission aged 16 I relapsed and had a stem cell transplant. Now I'm 31 and although not in the best of health from side effects of the chemo and radiotherapy (had a bad reaction to it all) I'm thankfully still here.

Amazing...no one can explain such a highly complicated topic in such a simple way like its done here....Great work... Keep it up

(from Tina Bigham) My husband passed away at tbe age of 59 from AML after a 2-year battle. I never really understood it competely, but I understand it a little better now. Thanks for this help.

I had AML when i was 12. I´m forever grateful to science, doctors and my friends and family for the fact i always had a positive surrounding and beat it after 8 months of intensive chemo. today i am 26 and so happy to be alive. if any person could say that he loves everyone and anything, it would be me. i just love everything, there's no other way to explain my feeling towards the world. The feeling of "i get to live and experience life after being so close to death" is unexplainable. however i did not always have this thought process after my treatment. I felt a lot of pain for a long time... Why me ? Why cant i do the same things as other kids? Why cant i have a normal childhood ? why cant i think the same way as other kids? why cant i focus on my dreams? why do i feel like little things don´t matter? why do i have no sense of direction? why am i feeling depressed? and loads of other thoughts that followed. I was never a victim but my thoughts for long time between the age of 16-24 were negative and for again, for a long time i felt like i was this victim that i told myself so often i wasn´t. If you are reading this and have a family member, friend or if you are going through this yourself, please speak out, to anyone! whether it be me, your dad, uncle, friend...Life after cancer can be hard, but we all need to make a choice to speak about it and seek the help that we may need.

My aunt just got this 5 hours ago today Im praying everything’s okay:(

Thank you so much for helping me learn about my cancer. Btw, I'm about five or six years into remission so don't worry. I had acute lymphoblastic leukemia.

Thank you for terrific presentation. We lost our daughter in July with AML, it having progressed from MDS. She first had symptoms at age 15 and passed away at 42. No one explained this to us.

This is the best tutorial I've ever received on Acute leukemias. I've studied this 2x in class and no professor has simplified it like osmosis did in this video.

This past Father's Day my dad was diagnosed with leukemia, and it ended up being a mixed phenotype, so he had both lymphoid and myeloid leukemia combined. It took him in about two weeks. I'm going into medicine, and normally this sort of thing is super fascinating to learn about, especially something so rare as mixed phenotype acute leukemia. But it just hits different when the patient in question is your dad. I'm glad to see stories of survivors here, and I hope everyone who sees this video holds their loved ones close.

2 years ago I was diagnosed with AML. Doctors called me dramatic and was saying since I was 18-19 years old that blood counts can fluctuate. It was until my hemoglobin dropped to 4.5 and a hospital stay that they finally saw it in my blood and sent me to Emory in Atlanta. I‘ve learned SOOO much about the disease and want to be able to help others like me through. After losing 4 friends from AML I’ve been pursuing a nursing degree for oncology and hopes to further this into a doctor of Hematology oncology. Thank you for your post and for helping me to further understand! To anyone watching this vid or reading this post that has been or is currently going through treatment for any type of leukemia, I’m praying for YOU!!💜

If you're here because you know what happen to Kyedae, Let's all pray for her Prayers up, Get well soon Kyedae

A classmate of mine passed away from AML just last week at age 23. Thank you for a great video.

Very good teacher. Explained everything so simply and clearly.

I lost my father due to Acute Monoblastic Leukaemia this week. It's been 5 days and i am trying to accept the fact that he isn't with me anymore. He was only diagnosed 4 months ago and he was completely okay whilst his treatment was going on until he caught a fever and then a lung infection which took him away from me. As a person from the medicine and health sciences field and my sister is a doctor herself we closely monitored our dad daily and made sure he lived the best life he could in his last days. I wish he was here because I wanted to do SO much for him. I will always regret it.

Thank you so much for this -Clear visual presentation -Smooth logical, concise flow It was So helpful! It’d help me, my colleagues and patients too!

Soo thankyou to the entire osmosis team!. You guys work soo hard to make any topic soo much informative and concise. God bless you all!

Osmosis is just the best. Teaching the hardest concepts in the simplest manner. Thank you so much

Beautifully explained, thank you very much for uploading!

im in remission from acute myeloii leukemia. three years now...still cautious though as its a five year mark an im only three years in...i wish you all who are suffering or in remission like myself for healing

AML in 2007 with a stem cell transplant. All is well thanks to God and all the amazing Dr's and nurses in Calgary.

The video is so beautifully made! Definitely managed to teach me a lot more than my lecturers! Thankyou for making this video

No one can explain this topic better than you🙏🙏🙏🙏🙏🙏🙏🙏

Medical lab science student who absolutely loves your videos!

these videos are legit so good, thank you

I have to really appreciate this lecture ,whataaa explanation it was!!!!

for anyone that is watching this because kyedae got diagnosed with myleoid lukemia, Please Pray or Send Guidance to her because she needs us right now.

i dont think that it could be understood more easier than this..to explain this topic in such easy manner is quite e difficult job.....kudos to team osmosis....

Beautifully presented.

Thanks for helping me in my presentation tomorrow. Really Appreciate it

Monday got exam for these.... very detailed video thanks

Thank you very much for this fabulous video ... Even it is 10 min it equals at least 1 hour lecture. I am very satisfied with it.

Thanks for the cool illustrations.❤

Great lecture Thanks for uploading 📚💓🙆🏻‍♀️

you are really the best, and you literally saved me!!!

Thank you so much for this video. 😀

There is no one in world who can give concept like this video👌🥳✌️🤩

Amazing explanation 🙏🏻 My son had that 7 years old Doing treatment right now

Very helpful. Thank you for sharing!

kyedae?

Wow RU-vid recommendations are super specific. My husband is in remission from AML.

Thank you so much.appreciate it.

this is an amazing explanation. thank you!

Amazing explanation thanks you sir .

okay is this osmosis or pathoma or maybe best of both worlds and I am just so happy! Thank you Medscape

Thank you. It was an awesome explanation.

i hope kyedae has a speedy recovery

Absolutely stunning explanation i am a med stud

Very great explanation ! Cheers 👍🏼

Thank you very much man! You saved my exam xD

My Brother is suffering from it. Currently undergoing chemotherapy. Lets all pray for his speedy recovery. InshaAllah

Great primer on leukemia. 👍🏻

Thank you

very nice and clear vedio

I'm watching this video because I had a tumor removed from my intestines (9cm) that according to test is myeloid leukemia in a mass. Two weeks later I got my bloodwork and bone marrow results back. Wbc count is dropping and bone marrow came back clean. It appears I'm cancer free at the moment without any treatment except removal of the tumor. They said I am a rare case and require alot more study and monitoring.

This was great! Thanks

Great work,Thank you :-)!

Best lecture

Hey thanks man with this. I was always unsure about the family of leukemias

many thanks

One of my best friends (we’re both 12) has aml leukaemia and it started off with her staying home a lot because they thought she had the flu but she didn’t obviously. She was away for atleast 3 months and was in and out of the hospital the whole time but none of her friends got to visit her or see her but she came back to school yesterday and found out she isn’t loosing her hair and she’ll be done chemo in January. She’s had over 5 bone marrows done and has a centre line I think it’s called which goes underneath her shirt. She’s the same person and you wouldn’t even know she has leukaemia/cancer if she didn’t tell you. A nurse from the hospital she was at told us all about it and said they are certain she’ll survive.

Thankyou so much😢

nice presentaion..im not totally familiar interms of medical aspect but its a very good presentation

you are God sent

I hoped that you would explain more about acute erytroblast leukemia, maybe you can include this later. I find it so hard to fint information about the AML M6 (Erytroblast)

Thank you❤❤❤

Excellent

very helpful!!!

I am so suprised that how a 10 min video is much instructiv than 1.5 hour lecture

Thank you so much! 28/7/2019 😁

Awesome video!!!! The title should be Acute Leukaemia though, not Acute Myeloid Leukaemia Again, many many thanks. This was extremely helpful 🙏🏽

JazakAllah kher

bless this channel! it's the only reason I'm passing my classes; Lord knows my professor is useless. 🙏

Im here because of kyedae tweeted that she got AML. Now im broken

i am an internal medicine resident. and whenever i need to revise something i still come here

Masterpiece ❤️😊

My blast count was 70% when they found my AML. Luckily I had a genetic mutation called inversion 16, and now I'm 4 years in remission.

My wife and I lost our just turned 2 year old son 7 months ago to Aml. He had MLL gene rearrangement or subtype KMT2A or 11q23. He had a translocation between chromosomes 6 and 11, t(6;11). He received cytarabine, daunorubicin, etoposide, gemtuzumab ozagamicin then mitoxNtrone and cytarabine. He relapsed after the second chemo which signified refractory Aml which had a poor prognosis. Decitabine with mylotarg was then used. He died shortly after from within 4 months of treatment. Some side effects he had were bloody nausea and diahrea. Horrible bloody mouth sores. He was in pain all over. His right eye was covered by a leukemia pool that ended up bleeding.He had a lot of liquid in his lungs which they thought was pnemonia. He ultimately died from a brain bleed within 24 hours caused we think by the chemo.

l am medical student. l like it very much

Please discuss about CML

Big hugs to those suffering with AML. ❤ patients and loved ones.

Am medical student thank you at last i understood

Recently my wife passed away at 52 years from Acute Myeloid leukemia. I am so sad.

My father entered the hospital three days ago after a fall and injuring his knee the next day a home nurse came to check on him and said he needed to go to the hospital right then by ambulance. He had a severe infection. When the specialist came in after he received his labs he asked if any doctor mentioned that he had ASL. We were shocked, so obviously no. And looking at his blood work in the last 8 years it was right there. Why did no Dr see this? As well my brother has a daughter who was born with Downs and was diagnosed with leukemia??????

You are genius

Thank you for the simple explanation. It was very helpful to grasp the information . Isn't Philadelphia chromosome seen in chronic myeloid leukaemia? 🤔🤔🤔

الله يباركلك ياشيخ💙💙💙👌

thanks

Aww nice information. My step daughter passed away with this a few days ago

Me an oral surgeon and expert on oral pathology ..watching this whole video for the hypertrophic gingiva due to blast infiltration

kyedae :(

Tqsmmm sir😍😍😍

My Mom passed away from a short diagnosis of AML after years with APA and MLS.

Necesito traduccion de éste video🙏

Dets good tho 🤔 Thnx for video Keep making video ✌️

You did not comment on the prognosis for myeloid.

pl make vedio on cml

I have myelocytes in my blood but the thing is my WBC isn’t up. So I’m not sure if i have it or not.

Is it like myeloid stem cell give rise to myeloblast but fails further development into granulocytes ?